Electron microscopic and histochemical studies on dystrophic masseter muscle

Masseter muscles from normal and dystrophic mice were investigated with the electron microscope and by the use of histochemical techniques for myosin ATPase and succinic dehydrogenase activity. The observations show that the muscle fibers arc severely affected in the masseter of the dystrophic mouse.     

ANAESTHESIA WITH FLUNITRAZEPAM AND KETAMINE

A double-blind trial was undertaken to compare the effects oftrimeprazine tartrate (2mgkg^–1 or 4mgkg^–1) plusatropine 0.03mgkg^–1 for oral preinedication of 192 childrenundergoing tonsillectomy. Demeanour before operation, side-effectsafter operation, recovery times and fluid balance were studied.Behaviour in the anaesthetic room and restlessness after operationwere unaffected by the dose given. There was less vomiting associatedwith 4mgkg^–1 compared with 2mg kg^–1. Prolonged recoverytimes occurred frequently in the two groups, 14% in the small-and 17% in the large-dose groups taking more than 10 h to recoverfull mental faculties. Fluid bal4nce was unaffected by the doseand prolonged recovery did not result in a reduction of urineoutput. Trimeprazine tartrate is not recommended for routinepremedication when early recovery is required.     

INCREASING INCIDENCE OF NEONATAL SEPTICEMIA: CAUSATIVE ORGANISM AND PREDISPOSING RISK FACTORS

ABSTRACT. Bennet, R., Eriksson, M. and Zetterstrom, R. (Department of Paediatrics, Karolinska Institute, St. Göran's Children's Hospital, Stockholm, Sweden). Increasing incidence of neonatal septicemia: Causative organism and predisposing risk factors. Acta Paediatr Scand, 70:207, 1981. –The incidence of neonatal septicemia in the referral area of St. Göran's Children's Hospital in Stockholm has been studied during a ten-year period (1969–1978). An increase was noticed during the period 1974–1978 in comparison with the preceding five-year period. The incidence per 1000 live births was 1.4 and 3.1, respectively. The incidence of osteoarthritis increased from 0.21 to 0.41 per 1000. Mortality rate from neonatal septicemia remained unchanged. Gram-negative organisms as an etiologic factor seemed to be decreasing while staphylococcal infections have increased. Group B streptococcal infection occurred with the same frequency during the whole period. The low incidence of enteric organisms might be related to the common practice of feeding the babies with milk from their own mothers. Perinatal risk factors were equally common in both five-year periods. The observed increase of the prevalence of neonatal septicemia caused by Staphylococcus aureus may be explained by a higher rate of survival of highly susceptible low-birthweight infants and other sick neonates treated in the neonatal intensive care unit.