全文获取类型
收费全文 | 5406篇 |
免费 | 479篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 62篇 |
儿科学 | 174篇 |
妇产科学 | 132篇 |
基础医学 | 756篇 |
口腔科学 | 46篇 |
临床医学 | 726篇 |
内科学 | 1047篇 |
皮肤病学 | 84篇 |
神经病学 | 601篇 |
特种医学 | 108篇 |
外科学 | 464篇 |
综合类 | 42篇 |
一般理论 | 13篇 |
预防医学 | 704篇 |
眼科学 | 132篇 |
药学 | 348篇 |
中国医学 | 11篇 |
肿瘤学 | 444篇 |
出版年
2024年 | 12篇 |
2023年 | 73篇 |
2022年 | 83篇 |
2021年 | 188篇 |
2020年 | 115篇 |
2019年 | 211篇 |
2018年 | 188篇 |
2017年 | 156篇 |
2016年 | 176篇 |
2015年 | 196篇 |
2014年 | 227篇 |
2013年 | 287篇 |
2012年 | 437篇 |
2011年 | 426篇 |
2010年 | 225篇 |
2009年 | 181篇 |
2008年 | 344篇 |
2007年 | 321篇 |
2006年 | 322篇 |
2005年 | 296篇 |
2004年 | 272篇 |
2003年 | 277篇 |
2002年 | 234篇 |
2001年 | 52篇 |
2000年 | 31篇 |
1999年 | 50篇 |
1998年 | 41篇 |
1997年 | 44篇 |
1996年 | 20篇 |
1995年 | 30篇 |
1994年 | 27篇 |
1993年 | 21篇 |
1992年 | 25篇 |
1991年 | 17篇 |
1990年 | 27篇 |
1989年 | 20篇 |
1988年 | 8篇 |
1987年 | 19篇 |
1986年 | 11篇 |
1984年 | 11篇 |
1983年 | 13篇 |
1982年 | 15篇 |
1981年 | 8篇 |
1980年 | 11篇 |
1979年 | 12篇 |
1978年 | 14篇 |
1977年 | 8篇 |
1970年 | 11篇 |
1967年 | 11篇 |
1965年 | 6篇 |
排序方式: 共有5894条查询结果,搜索用时 15 毫秒
91.
Alison T. Stopeck Karim Fizazi Jean-Jacques Body Janet E. Brown Michael Carducci Ingo Diel Yasuhiro Fujiwara Miguel Martín Alexander Paterson Katia Tonkin Neal Shore Paul Sieber Frank Kueppers Lawrence Karsh Denise Yardley Huei Wang Tapan Maniar Jorge Arellano Ada Braun 《Supportive care in cancer》2016,24(1):447-455
92.
Use of biomarkers in clinical practice has proved extremely valuable and is a rapidly expanding field. However, despite the huge potential of biomarkers, for juvenile idiopathic arthritis (JIA) there are currently no validated paediatric biomarkers available to help with setting up a more tailored approach on which drug choice could be based, to achieve remission early in the course of disease. Early remission reduces burden of disease, limits side effects from toxic and unnecessary medication, and, most importantly, enhances quality of life. Several studies have suggested promising biomarkers: these may be a protein, cellular component, mRNA, or genetic component, for example a single nucleotide polymorphism (SNP). Here we describe recent developments in the use of biomarkers for JIA and their potential to assist in management of disease by predicting disease phenotype, severity, progression, and response to treatment, and determining when patients have reached stable remission and can safely discontinue treatment. 相似文献
93.
94.
Grant Christie Stella Black Lucy Dunbar Justin Pulford Amanda Wheeler 《International journal of mental health and addiction》2013,11(2):232-246
Adolescent mental health workers are generally poor at identifying and treating co-existing alcohol and other drug (AOD) disorder. This study aimed to evaluate the utility and acceptability of an AOD screening and brief intervention (BI) training package delivered to child and adolescent mental health workers and its impact on relevant attitudes, skills and knowledge. Quantitative data was collected before and after the BI training using a 55-item questionnaire. Focus groups explored issues around AOD screening and BI implementation in practice. The questionnaire and focus group were repeated 10 months later to ascertain change in behaviour. The BI training was well-received and led to improvements in attitudes, skills and knowledge around AOD screening and BI in youth mental health practitioners. Positive change in participants’ attitudes to performing screening and BI were demonstrated. Low response rates at follow-up limited analysis of behaviour change. 相似文献
95.
This paper reports on participants’ views regarding factors contributing to the vulnerability of teenagers with intellectual disability to sexual abuse. The study took place at two special schools located in a village of KwaZulu-Natal. Data were gathered using by individual interviews, which were conducted in a face-to-face manner with life orientation teachers (8), school nurses (2), a clinical psychologist at the local hospital, and social workers (2). The interviews were also conducted with two parents, a traditional healer and spiritual diviner. Data was thematically analysed. The vulnerability factors were grouped into three broad categories, namely: individual, family and community factors. The existence of a number of vulnerability factors suggests that efforts to mitigate the problem should occur at various levels, with which an individual is interacting. 相似文献
96.
97.
Charlotte Bickler Stuart A’Hara Joan Cottrell Lucy Rogers Jon Bridle 《Conservation Genetics Resources》2013,5(4):1185-1187
The cowslip (Primula veris L., Primulaceae) is a distylous perennial plant with a self-incompatibility system making it an obligate outbreeder. It is found in threatened grassland habitats that are becoming increasingly fragmented. Microsatellite discovery was performed using next generation sequence technologies. We present 13 novel microsatellite markers that have been optimised for P. veris. The loci show clear polymorphic banding patterns, exhibiting between 2 and 12 alleles, with observed heterozygosity values ranging from 0.296 to 0.889. These markers will facilitate the assessment of genetic diversity and population structure of P. veris populations. 相似文献
98.
Lucy Mackillop Lise Loerup Katy Bartlett Andrew Farmer Oliver J. Gibson Jane E. Hirst Yvonne Kenworthy Dev A. Kevat Jonathan C. Levy Lionel Tarassenko 《Journal of diabetes science and technology》2014,8(6):1105-1114
Gestational diabetes mellitus (GDM) is defined as new onset or recognition of glucose intolerance in pregnancy. Evidence supports tight blood glucose regulation to prevent adverse maternal and fetal outcomes. Finger-prick blood glucose (BG) testing with frequent clinic review remains the most common method of managing diabetes in pregnancy. The prevalence of GDM is rising globally, pressuring resource-limited services. We have developed an intuitive, interactive, reliable, and accurate management system to record BG measurements and deliver management of GDM remotely. Following an initial scoping phase, a prototype software application was developed using an Android smartphone with BG meter linkage via Bluetooth. A custom website was built for clinician review of the data transmitted by the smartphone. After system refinement, further evaluation was undertaken for usability and reliability in a 48-patient service development project. Women used the system for an average of 13.1 weeks. In all, 19 686 BG measures were transmitted, 98.6% of which had a meal tag. A total of 466 text messages were transmitted. A mean of 30 BG readings per woman per week were transmitted, and 85% of women submitted the minimum requirement of 18 readings per week. We have developed a novel, real-time, smartphone-based BG monitoring management system that allows clinician review of real-time patient-annotated BG results. Results indicate high usage and excellent compliance by women. Robust clinical, economic, and satisfaction evaluations are required. To address these requirements, we are currently conducting a randomized controlled pilot trial. 相似文献
99.
100.
Nancy Poole Lorraine Greaves Natasha Jategaonkar Lucy McCullough Cathy Chabot 《Substance use & misuse》2013,48(8-9):1129-1150
This study investigated the connections between stressors, substance use, and experience of violence among women (N = 125) who accessed help from domestic violence shelters in British Columbia, Canada between October 2001 and June 2003. Changes in substance use and stressors following a shelter stay were explored, using both qualitative and quantitative methods. Women generally decreased their use of alcohol and stimulants, and this change was found to be integrally connected to social and structural supports made available to them. Future research that augments current stress models of addiction by considering social and structural factors that come into play in women's substance use and domestic violence is suggested. The study's limitations are noted. 相似文献