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Mariaelena Pierobon Mariam Barak Sahel Hazrati Kathryn H. Jacobsen 《Jornal de pediatria》2013,89(1):100-107
ObjectiveThis study investigated the association between alcohol and violence among Argentine youth.MethodsData from the 2007 Argentina Global School-based Student Health Survey (GSHS), a nationally representative survey of middle school students, were examined using age-adjusted logistic regression models.ResultsOf the 1,328 participating students aged 13 to 15 years old, 51.9% reported drinking alcohol in the previous month, with higher rates among males (p = 0.04) and older students (p < 0.01). Both male and female drinkers were nearly twice as likely as non-drinkers to report being physically attacked, being in a physical fight, and having thoughts about self-directed violence. Among drinkers, those who reported poor mental health, were victims of bullying, used tobacco or drugs, or skipped school without per- mission were approximately twice as likely as other drinkers to have engaged in violent activities.ConclusionPublic health interventions targeting violence among young adolescents should be developed in combination with alcohol education programs. 相似文献
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Vasilevskaya Anna Taghdiri Foad Multani Namita Ozzoude Miracle Tarazi Apameh Khodadadi Mozhgan Wennberg Richard Rusjan Pablo Houle Sylvain Green Robin Colella Brenda Blennow Kaj Zetterberg Henrik Karikari Thomas Mikulis David Hazrati Lili-Naz Kovacs Gabor G. Davis Karen Deborah Tator Charles Tartaglia Maria Carmela 《Journal of neurology》2022,269(10):5582-5595
Journal of Neurology - Considering the wide range of outcomes following sport-related concussions, biomarkers are needed to detect underlying pathological changes. The objective was to analyze the... 相似文献
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H Mohammadzadeh Hajipirloo A Bozorgomid T Alinia KH Hazrati Tappeh R Mahmodlou 《Iranian Journal of Parasitology》2013,8(2):323-326
Background
The aim of this study was to determine the prevalence of hydatidosis in west Azerbaijan, Iran during a 10 year period (2000-2009).Methods
We surveyed medical records of infected patients with hydatid cyst who had been operated in four hospitals in Urmia City, the capital of West Azerbaijan Province, Iran. Several parameters were analyzed including age, sex, place of residency, hospitalization time, and the location of cysts.Results
Of 294 cases, 53.3% were female and 46.7% were male with the mean age of 39.4 years (5–93). The average number of operated cysts per year was 29.4 (0.98/100,000 of population). The most affected age group was 20-30 year olds (18.7% of the cases). Cysts were localized in liver and lung in 57.5% and 21.8% of cases respectively and the average hospitalization time was 9 days. Single organ involvement was seen in the majority of patients and 28 (9.5%) cases had multiple involvement. The distribution of residence in patients showed 108 (36.9%) of them to have urban origin and 185 (63.1%) were rural residents. The lowest number (n = 17) and the highest number of operation (n= 48) recorded in 2000 and 2007, respectively.Conclusion
The prevalence of hydatidosis is high in this city and further studies are needed for evaluation of economic burden and risk factors for CE in this region. 相似文献66.
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Abdolkazem Neisi Mohammad Shirmardi Esmaeil Idani Gholamreza Goudarzi Sadegh Hazrati 《Toxin reviews》2018,37(3):243-250
The aim of this study is to survey the concentrations of air pollutants in rural and urban areas in Ahvaz city during two seasons. We used ANOVA to determine the differences between the areas. Paired t-test was used to compare the concentrations of the air pollutants in cold season and hot season. The concentration of the air pollutants in cold season was higher than warm season except for O3. Mobile vehicles represent the major source of air pollution in many areas, and the concentrations of traffic pollutants are greater near urban areas. The trend of changes in PM concentration in cold and warm seasons depends on dust storms occurrence. 相似文献
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Philippe Huot MD PhD FRCPC DABPN Tom H. Johnston PhD Naomi P. Visanji PhD Tayyeba Darr BSc Donna Pires RVT Lili‐Naz Hazrati MD PhD FRCPC Jonathan M. Brotchie PhD Susan H. Fox MB ChB MRCP PhD 《Movement disorders》2012,27(6):735-742
Visual hallucinations are common in advanced Parkinson's disease (PD). The pathophysiology of visual hallucinations may involve enhanced serotonergic neurotransmission. The atypical antipsychotics clozapine and quetiapine, which have affinity for 5‐HT2A and 5‐HT1A receptors, are effective against visual hallucinations in PD. 5‐HT2A receptors are increased in ventral visual pathways in PD patients with visual hallucinations, and we hypothesized that 5‐HT1A receptors were also involved in visual hallucinations in PD. Autoradiographic binding using [3H]‐WAY‐100,635 and NAN‐190 was performed in brain sections from 6 PD patients with visual hallucinations, 6 PD patients without visual hallucinations, and 5 age‐matched controls. All PD subjects had been treated with L ‐dopa. Brain areas studied were the orbitofrontal, inferolateral temporal, and motor cortices, as well as the striatum, globus pallidus, substantia nigra, and thalamus. 5‐HT1A‐binding levels were dramatically increased in the ventral visual pathways of all PD patients compared with controls (0 vs 11 and 0 vs 100 nmol/mg, respectively; both P < .05). There was no significant difference in 5‐HT1A‐binding levels in PD patients with visual hallucinations compared with PD patients without visual hallucinations or with controls in any of the brain areas studied (P > .05). Gross abnormalities in 5‐HT1A levels in ventral visual areas occurred in all PD patients exposed to L ‐dopa. However, as there was no difference in 5‐HT1A‐binding levels between hallucinators and nonhallucinators, alterations in 5‐HT1A receptor levels may not contribute specifically to visual hallucinations in PD. However, the discrete anatomical distribution of rises to the ventral visual areas suggests some role in predisposing to visual hallucinations. © 2012 Movement Disorder Society 相似文献
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Keller MJ Guzman E Hazrati E Kasowitz A Cheshenko N Wallenstein S Cole AL Cole AM Profy AT Wira CR Hogarty K Herold BC 《AIDS (London, England)》2007,21(4):467-476
OBJECTIVE: Vaginal microbicides should protect against infection without disrupting the mucosal environment or its mediators of host defense. The objective of this study was to examine the effect of 14 daily applications of 0.5% PRO 2000 or placebo gel on mediators of mucosal immunity and intrinsic antimicrobial activity. DESIGN AND METHODS: A randomized, prospective, double-blind, placebo-controlled study was conducted among 24 healthy, abstinent women. Levels of cytokines, chemokines, defensins, and other protective factors and intrinsic antimicrobial activity were determined in cervicovaginal lavage samples collected on study days 0, 7, 14, and 21. RESULTS: No increase in pro-inflammatory cytokines was observed. Rather cytokines and protective factors including interleukin (IL)-1 receptor antagonist, immunoglobulins and human beta-defensin 2 were lower in the drug compared with the placebo group. All of the mediators returned towards baseline on day 21. Women who were cycling had lower levels of most proteins on study days 7 and/or 14 compared with women on oral contraceptives; however, the magnitude of decline was greater in women who received PRO 2000 compared with placebo gel. The reduction in protective factors was not associated with a loss in the intrinsic anti-viral (HIV or herpes simplex virus) activity or anti-bacterial activity (Escherichia coli or Staphylococcus aureus). CONCLUSION: In contrast to experience with nonoxynol-9, PRO 2000 did not trigger an inflammatory response in cervicovaginal secretions. There was a modest reduction in mucosal immune mediators, but this loss was not associated with a reduction in intrinsic antimicrobial activity. 相似文献
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