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排序方式: 共有678条查询结果,搜索用时 31 毫秒
671.
672.
Dalamaga M Karmaniolas K Panagiotou A Hsi A Chamberland J Dimas C Lekka A Mantzoros CS 《Cancer causes & control : CCC》2009,20(2):193-199
Accumulating evidence supports a role for obesity in the etiology of multiple myeloma (MM). The distinct possibility exists
that obesity may be linked to MM through altered adipokine secretion and circulating levels, one of which, adiponectin, has
a protective role in several malignancies, including leukemia. In this case–control study, we investigated the role of serum
adiponectin, resistin, and leptin levels in the etiopathogenesis of MM and we explored their association with several established
prognostic factors. Seventy three patients with incident, histologically confirmed MM and 73 controls matched on gender and
age were studied between 2001 and 2007, and blood samples were collected. Serum adiponectin, leptin, resistin, as well as
MM prognostic parameters were determined. Statistical analysis of the data was performed using univariate and multivariate
analyses. Lower serum adiponectin and resistin levels were associated with higher risk of MM by bivariate analysis and after
adjusting for age, gender, BMI, and serum levels of leptin (p < 0.0001). Adiponectin may have a protective role in MM, whereas leptin was not associated with risk for MM at a comparable
level of significance and resistin levels may be decreased via a compensatory mechanism. Further studies are needed to confirm
these associations and to explore the mechanisms underlying adiponectin’s role in MM and plasma cell dyscrasias. 相似文献
673.
674.
Ahmad Haidar PhD Jean-Francois Yale MD Leif Erik Lovblom MSc Nancy Cardinez NP Andrej Orszag MD C. Marcelo Falappa MD Nikita Gouchie-Provencher RN Michael A. Tsoukas MD Anas El Fathi PhD Jennifer Rene RN Devrim Eldelekli BM Sebastien O. Lanctôt Daniel Scarr BSc Bruce A. Perkins MD 《Diabetes, obesity & metabolism》2021,23(6):1272-1281
675.
Behnam N. Tehrani MD Abdulla A. Damluji MD PhD MPH Matthew W. Sherwood MD MHS Carolyn Rosner NP Alexander G. Truesdell MD Kelly C. Epps MD Edward Howard MD Scott D. Barnett PhD Anika Raja BS Christopher R. deFilippi MD Charles E. Murphy MD Christopher M. O'Connor MD Wayne B. Batchelor MD MHS 《Catheterization and cardiovascular interventions》2021,97(7):1354-1366
676.
Pei-Ying Lin MD Warren Kaplan PhD JD Chia-Hung Lin MSN NP Yen-Han Lee MPH PhD 《Public health nursing (Boston, Mass.)》2023,40(4):517-527
Taiwan's National Health Insurance (NHI) is a widely acclaimed universal healthcare system. In the past few years, particularly following the COVID-19 outbreak, challenges related to maintaining the NHI system have surfaced. Since 2020, NHI has faced a series of challenges, including excessive patient visits to the hospital emergency department, a lack of an effective primary care and referral system, and a high turnover rate of healthcare workers. We review major problems related to Taiwan's NHI, emphasizing input from frontline healthcare workers. We provide recommendations for potential policies addressing the concerns around NHI, for example, strengthening the role of primary care services under the NHI administration, reducing the high turnover rate of healthcare workers, and increase the premium and copayments. We hope that this policy analysis may allow policymakers and scholars to understand both the merits and critical problems related to NHI from the clinical perspective. 相似文献
677.
678.
Friyana K. Bhabha MBBS FACD Christopher McCormack MBBS FACD Belinda A. Campbell MBBS MMed FRANZCR Stephen Lade MBBS FRCPA Odette Buelens RN BN PGDipNur MN NP Carrie Van Der Weyden MBBS FRACP FRCPA H. Miles Prince MBBS MD FRACP FRCPA AFRCMA MACD FAHMS 《The Australasian journal of dermatology》2023,64(2):194-203
The CD30-postive lymphoproliferative disorders, including lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma, account for up to 30% of all cutaneous T-cell lymphomas (CTCLs) and are the second most common form of CTCLs after mycosis fungoides. Both conditions differ in their clinical presentations; however, they share the expression of the CD30 antigen as a common immunophenotypic hallmark. There is a wide spectrum of management options depending on factors such as extent of disease, staging and treatment tolerability. This Clinical Practice Statement is reflective of the current clinical practice in Australia. 相似文献