Abdelkarim S. Aloweidi  Sami A. Abu-Halaweh  Ghazi M. Al-Edwan  Saddam H. AL Demour  Laith T. Abu Mahfuz  Osama N. Noubani  Mohammad M. Al Rwaidi  Isam K. Bsisu  Mohammad M. Abufaraj 《Saudi medical journal》2021,42(6):629

Objectives:To compare sedoanalgesia achieved using propofol-fentanyl-ketamine (PFK) combination with general anesthesia (GA) in terms of safety, hemodynamic stability, and perioperative complications.Methods:Patients in the GA group were anesthetized using fentanyl (2 μg kg-1) and propofol (2 mg kg-1). The PFK group was anesthetized using a mixture of which each one ml contains 0.005 mg of fentanyl, 5 mg of propofol, 5 mg of ketamine, and 2 mg of lidocaine. Patients received an initial dose of 0.05 ml kg-1, followed by 0.05 mg kg-1 60 seconds later. Maintenance boluses of 0.025 ml kg-1 were administered every 3-5 minutes. Respiration occurred spontaneously through a simple face mask with 3 L min-1 O₂.Results:The GA group had 37 (37%) patients develop hypotensive episodes, compared to one (1%) episode in the PFK group (p<0.001). Five (5%) patients in the PFK group had an episode of transient O₂ desaturation, compared to one (1%) patient in the GA group (p=0.212). The duration of induction and termination of anesthesia were significantly shorter in the PFK group (p<0.001).Conclusion:The PFK combination herein described is safe, effective, and provides intraoperative hemodynamic stability in patients with multiple comorbidities undergoing urological procedures.  相似文献   

    

Abdallah Y. Naser  Eman Zmaily Dahmash  Rabaa Al‐Rousan  Hassan Alwafi  Hamzeh Mohammad Alrawashdeh  Imene Ghoul  Anwer Abidine  Mohammed A. Bokhary  Hadeel T. AL‐Hadithi  Dalia Ali  Rasha Abuthawabeh  Ghada Mohammad Abdelwahab  Yosra J. Alhartani  Haneen Al Muhaisen  Ayah Dagash  Hamad S. Alyami 《Brain and Behavior》2020,10(8)

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Ameera G. A. AL Mohammadi  Eraqi R. Khannoon  Susan E. Evans 《Journal of anatomy》2020,236(1):117-131

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Anas S. AL Dehailan 《Neurosciences (Riyadh, Saudi Arabia)》2019,24(3):236

Tremor is the most common and frequently reported movement disorder in multiple sclerosis (MS). Paroxysmal dystonia (PD), also known as painful tonic spasm (PTS), is a relatively less common but well-recognized movement disorder in multiple sclerosis (MS). These are characterized by episodic attacks of involuntary flexion, extension movements of body. Such paroxysmal symptoms as an initial presenting feature raise many differential diagnoses and can often be mistaken as epileptic seizures as well as psychogenic events and may sometimes lead to delay in diagnosis as well. Diagnosis is clinical with the help of supportive investigations to rule out other paroxysmal disorders, especially epileptic seizures. We describe a case of a young lady, who was referred to us as a case of refractory seizure and diagnosed as having paroxysmal dystonia as a first manifestation of MS, with complete resolution of her symptoms after successful treatment with anti-epileptic drugs.

Paroxysmal dystonia (PD), also called Painful tonic spasm (PTS), is a well-recognized and the most frequently observed movement disorder in multiple sclerosis.1 The PD is classified as 4 types according to the precipitating factors, phenomenology, duration of attacks, and etiology. Paroxysmal kinesigenic dyskinesia (PKD) is induced by sudden movement, paroxys¬mal non-kinesigenic dyskinesia occurs spontaneously, paroxysmal exertion-induced dyskinesia appears after prolonged exercise, and paroxysmal hypnogenic dyskinesia occurs during sleep.2 These disorders have often been misdiagnosed as partial onset epilepsy initially and later identified as movement disorder secondary to MS. Treatment of underlying disease along with symptomatic treatment may alleviate the symptoms significantly. We described a case of a young lady who was referred to us as a case of psychogenic non-epileptic events. Diagnosis of MS manifesting with PD was established. She was started on disease modifying therapy for MS as well as Carbamazepine for her PD. She showed a remarkable improvement on these treatments and was followed up in MS clinic with no new MS relapse or recurrence of PD for 18 months after the initial presentation.  相似文献   

    

Noordeen Shoqirat  Deema Mahasneh  Charleen Singh  Ahmad Yahya AL‐Sagarat  Sakhaa Habashneh 《International journal of nursing practice》2019,25(5)

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D.H. Arabiat  L. Whitehead  M. AL Jabery  A. Towell‐Barnard  L. Shields  E. Abu Sabah 《International nursing review》2019,66(3):329-337

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Manal T. Al‐Obaidi  Zainab H. Ali  Wasan I. AL‐Saadi  Estabraq A. R. AL‐Wasiti  Hayder Al‐Aubaidy 《Journal of clinical pharmacy and therapeutics》2019,44(4):618-622

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Sadeq AL‐Fayyadh 《Nursing Open》2019,6(4):1346-1353

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Ahmad AL‐Sagarat  Yousef Qan'ir  Manar AL‐Azzam  Hala Obeidat  Anas Khalifeh 《Nursing forum》2018,53(3):304-313

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Fernanda A. Correa  Alexander AL Jorge  Marilena Nakaguma  Ana PM Canton  Silvia S Costa  Mariana F Funari  Antonio M Lerario  Marcela M Franca  Luciani R Carvalho  Ana CV Krepischi  Ivo JP Arnhold  Carla Rosenberg  Berenice B Mendonca 《Clinical endocrinology》2018,88(3):425-431

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