全文获取类型
收费全文 | 5769篇 |
免费 | 458篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 49篇 |
儿科学 | 121篇 |
妇产科学 | 101篇 |
基础医学 | 677篇 |
口腔科学 | 67篇 |
临床医学 | 776篇 |
内科学 | 1185篇 |
皮肤病学 | 93篇 |
神经病学 | 475篇 |
特种医学 | 166篇 |
外科学 | 981篇 |
综合类 | 46篇 |
一般理论 | 3篇 |
预防医学 | 517篇 |
眼科学 | 86篇 |
药学 | 434篇 |
中国医学 | 7篇 |
肿瘤学 | 454篇 |
出版年
2023年 | 59篇 |
2022年 | 102篇 |
2021年 | 317篇 |
2020年 | 180篇 |
2019年 | 243篇 |
2018年 | 270篇 |
2017年 | 190篇 |
2016年 | 166篇 |
2015年 | 250篇 |
2014年 | 259篇 |
2013年 | 364篇 |
2012年 | 463篇 |
2011年 | 491篇 |
2010年 | 236篇 |
2009年 | 165篇 |
2008年 | 291篇 |
2007年 | 278篇 |
2006年 | 298篇 |
2005年 | 217篇 |
2004年 | 206篇 |
2003年 | 185篇 |
2002年 | 156篇 |
2001年 | 81篇 |
2000年 | 66篇 |
1999年 | 63篇 |
1998年 | 33篇 |
1997年 | 30篇 |
1996年 | 31篇 |
1995年 | 31篇 |
1994年 | 12篇 |
1993年 | 20篇 |
1992年 | 45篇 |
1991年 | 41篇 |
1990年 | 41篇 |
1989年 | 33篇 |
1988年 | 28篇 |
1987年 | 27篇 |
1986年 | 24篇 |
1985年 | 32篇 |
1984年 | 27篇 |
1983年 | 13篇 |
1979年 | 15篇 |
1978年 | 9篇 |
1974年 | 11篇 |
1973年 | 13篇 |
1971年 | 13篇 |
1970年 | 12篇 |
1968年 | 14篇 |
1967年 | 8篇 |
1966年 | 13篇 |
排序方式: 共有6238条查询结果,搜索用时 15 毫秒
81.
82.
83.
84.
85.
Aaron S. Farberg Mary A. Hall Leah Douglas Kyle R. Covington Sarah J. Kurley Robert W. Cook 《Current medical research and opinion》2020,36(8):1301-1307
AbstractObjective: To integrate gene expression profiling into the management of high-risk cutaneous squamous cell carcinoma (cSCC) within the National Comprehensive Cancer Network (NCCN) guidelines to improve risk-aligned management recommendations.Methods: A cohort of 300 NCCN-defined high-risk cSCC patients, along with the American Joint Committee on Cancer (AJCC) T stage, Brigham and Women’s Hospital (BWH) T stage, and known patient outcomes were analyzed. Risk classifications using a validated 40-gene expression profile (40-GEP) test and T stage were applied to NCCN patient management guidelines. Risk-directed patient management recommendations within the NCCN guidelines framework were aligned based on risk for metastasis.Results: Of the 300 NCCN high-risk cSCC patients, 159 (53.0%) were 40-GEP Class 1 and AJCC T1-T2, and 173 (57.7%) were Class 1 and BWH T1-2a, indicating low risk for metastasis and, thereby, suggesting low management intensity. The 40-GEP integration suggested high intensity management for only 24 (8.0%) patients (all Class 2B), and moderate intensity management for the remainder of the cohort.Conclusions: The 40-GEP test can be integrated within existing NCCN guideline recommendations for managing cSCC patients to help refine risk-directed management decisions. Integration of the 40-GEP test would allow >50% of this NCCN-defined high-risk cohort to be managed with the lowest intensity recommendations within the broad NCCN guidelines. High intensity management was deemed risk-appropriate for a small subpopulation (8.0%). This study demonstrates that the 40-GEP test, in combination with T stage, has clinical utility to impact patient management decisions in NCCN high-risk cSCC for improving risk-aligned management within the NCCN guidelines framework. 相似文献
86.
87.
Alexander Ayala Kyle Tegtmeyer Giancarlo Atassi Elizabeth Powell 《The Journal of emergency medicine》2021,60(5):661-668
BackgroundProlonged emergency department (ED) wait times could potentially lead to increased morbidity and mortality. While previous work has demonstrated disparities in wait times associated with race, information about the relationship between experiencing homelessness and ED wait times is lacking.ObjectivesThe purpose of this study was to explore the relationship between residence status (undomiciled vs. domiciled) and ED wait times. We hypothesized that being undomiciled would be associated with longer wait times.MethodsWe obtained data from the National Hospital Ambulatory Medical Care Survey from 2014 to 2017. We compared wait times in each triage category using t tests. We used multivariate linear regression to explore associations between residence status and wait times while controlling for other patient- and hospital-level variables.ResultsOn average, undomiciled patients experienced significantly longer mean ED wait times than domiciled patients (53.4 vs. 38.9 min; p < 0.0001). In the multivariate model, undomiciled patients experienced significantly different wait times by 15.5 min (p = 0.0002). Undomiciled patients experienced increasingly longer waits vs. domiciled patients for the emergent and urgent triage categories (+33.5 min, p < 0.0001, and +22.7 min, p < 0.0001, respectively).ConclusionsUndomiciled patients experience longer ED wait times when compared with domiciled patients. This disparity is not explained by undomiciled patients seeking care in the ED for minor illness, because the disparity is more pronounced for urgent and emergent triage categories. 相似文献
88.
Ticiana A. Leal Angela C. Argento Krish Bhadra D. Kyle Hogarth Julia Grigorieva Rachel M. Hartfield 《Current medical research and opinion》2020,36(9):1497-1505
Abstract
Objective
Timely assessment of patient-specific prognosis is critical to oncology care involving a shared decision-making approach, but clinical prognostic factors traditionally used in NSCLC have limitations. We examine a proteomic test to address these limitations. 相似文献89.
Nicole Bohm Charles Makowski Mario Machado Adam Davie Nelson Seabrook Lee Wheless Benjamin Bevill Bradley Clark T. Rogers Kyle III 《Antimicrobial agents and chemotherapy》2014,58(8):4902-4903
A patient receiving daptomycin developed asymptomatic transaminitis and hyperbilirubinemia without concurrent multiorgan dysfunction or elevation of his creatinine kinase level. After ruling out other etiologies, the liver injury was attributed to daptomycin and was subsequently resolved. A single-center retrospective cohort analysis of baseline and follow-up liver function panels (n = 614) from all admissions from 2008 to 2013 during which daptomycin was administered did not reveal any other cases of probable or definite drug-induced liver injury associated with daptomycin. 相似文献
90.