全文获取类型
收费全文 | 3815篇 |
免费 | 173篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 291篇 |
妇产科学 | 64篇 |
基础医学 | 472篇 |
口腔科学 | 144篇 |
临床医学 | 242篇 |
内科学 | 650篇 |
皮肤病学 | 54篇 |
神经病学 | 238篇 |
特种医学 | 98篇 |
外科学 | 510篇 |
综合类 | 93篇 |
一般理论 | 2篇 |
预防医学 | 219篇 |
眼科学 | 119篇 |
药学 | 549篇 |
中国医学 | 18篇 |
肿瘤学 | 217篇 |
出版年
2023年 | 13篇 |
2022年 | 62篇 |
2021年 | 96篇 |
2020年 | 58篇 |
2019年 | 64篇 |
2018年 | 83篇 |
2017年 | 64篇 |
2016年 | 67篇 |
2015年 | 91篇 |
2014年 | 152篇 |
2013年 | 172篇 |
2012年 | 253篇 |
2011年 | 269篇 |
2010年 | 151篇 |
2009年 | 140篇 |
2008年 | 211篇 |
2007年 | 223篇 |
2006年 | 171篇 |
2005年 | 175篇 |
2004年 | 146篇 |
2003年 | 136篇 |
2002年 | 121篇 |
2001年 | 110篇 |
2000年 | 98篇 |
1999年 | 83篇 |
1998年 | 31篇 |
1997年 | 32篇 |
1996年 | 21篇 |
1995年 | 15篇 |
1994年 | 12篇 |
1993年 | 16篇 |
1992年 | 67篇 |
1991年 | 56篇 |
1990年 | 58篇 |
1989年 | 52篇 |
1988年 | 47篇 |
1987年 | 41篇 |
1986年 | 53篇 |
1985年 | 38篇 |
1984年 | 27篇 |
1983年 | 22篇 |
1981年 | 14篇 |
1979年 | 16篇 |
1977年 | 16篇 |
1976年 | 11篇 |
1974年 | 17篇 |
1973年 | 19篇 |
1972年 | 15篇 |
1970年 | 9篇 |
1969年 | 10篇 |
排序方式: 共有3995条查询结果,搜索用时 15 毫秒
41.
A one day old neonate with a short colon, associated exomphalos minor; bifid scrotum and ileovesical fistula is reported. 相似文献
42.
A patient who reported with a slowly growing swelling ovr thee lateral aspect of the left ankle, was investigated and diagnosed to have a giant cell tumour which was confirmed on FNAC. The tumour was managed with excision biopsy and reconstruction. The case is being reported for its rare site of occurrence. 相似文献
43.
Kulkarni AV Chumas PD Drake JM Armstrong DC 《The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques》1999,26(1):40-43
OBJECTIVE: One of the difficulties with lumboperitoneal (LP) shunts has been non-invasively ascertaining shunt function. It has been previously reported that in the presence of a functioning LP shunt the perimesencephalic cisterns become obliterated--the "absent cistern sign". In order to more rigorously test this association we performed a retrospective analysis of LP shunt patients at the Hospital for Sick Children, Toronto. METHODS: The CT scans of all patients undergoing LP shunting over a 17 year period were reviewed. The "absent cistern sign" and ventricular size were compared against the results of either an isotope shunt study or surgical findings performed within 2 days of the CT. RESULTS: There were 38 CT scans (27 patients) performed within 2 days of an isotope shunt study and 15 CT scans (14 patients) performed within 2 days of a surgical intervention. These results give the absent cistern sign a sensitivity of 75% and a specificity of 57% when compared to the shunt isotope findings and a sensitivity of 100% and a specificity of 50% when compared to the surgical findings. Over 30% of the CT scans showed ventriculomegaly in the presence of a functioning shunt and, conversely, nearly 45% of the CT scans had normal or small lateral ventricles in the presence of a malfunctioning shunt. CONCLUSIONS: The "absent cistern sign" appears to reliably rule out a completely blocked shunt, but is less reliable in detecting a normal or partially obstructed shunt. Ventricular size correlates poorly with LP shunt function. 相似文献
44.
45.
Kulkarni RW Wollstein R Tayar R Citron N 《The Journal of bone and joint surgery. British volume》1999,81(1):85-90
We studied 45 patients with 46 fractures of the scaphoid who presented sequentially over a period of 21 months. MRI enabled us to relate the pattern of the fracture to the blood supply of the scaphoid. Serial MRI studies of the four main patterns showed that each followed a constant sequence during healing and failure to progress normally predicted nonunion. 相似文献
46.
OBJECTIVE AND IMPORTANCE: Posterior fossa endodermal cysts are rare. They are located in the midline, in ventral or ventrolateral locations, or intrinsic to the neural axis. Accordingly, various theories of embryogenesis have been proposed. We report the first case of an extradural, dorsolaterally situated endodermal cyst. CLINICAL PRESENTATION: An adult male patient presented with a short history of headache and cerebellar ataxia. Neuroimaging revealed an extra-axial cystic posterior fossa mass. INTERVENTION: An entirely extradural cyst was found and was totally excised. Immunohistochemistry confirmed the diagnosis of endodermal cyst. CONCLUSION: The extradural, dorsal location of the endodermal cyst suggests gaps at the cranial end of the notochord causing ectodermal-endodermal adhesions during early gastrulation and the persistence of endodermal remnants in the dorsal mesenchyme of the blastemal cranium. The literature is reviewed, and proposed theories of embryogenesis are discussed. 相似文献
47.
Naveen K. Jain Chandrashekhar S. Patil R. E. Kartasasmita M. Decker J. Lehmann Shrinivas K. Kulkarni 《Drug development research》2004,61(2):66-78
Naproxen‐2‐nitrooxyethylester (S‐(+)‐2‐(6‐methoxy‐2‐naphthyl)propanoic acid‐2‐nitrooxyethylester, LE‐EK06) was synthesized from naproxen and 2‐nitrooxyethylbromide as a novel nitric oxide–releasing derivative of naproxen. Molar equivalents of LE‐EK06 (6.93–27.73 mg/kg, p.o.) to naproxen dose‐dependently exhibited greater antinociceptive activity in comparison to naproxen in a writhing assay. The compound (5.54–22.18 mg/kg, p.o.) showed greater anti‐inflammatory activity at 2 h after as comparable to its effect at 4 h after carrageenan challenge in rats. Further, LE‐EK06 (9.45 mg/kg, p.o.) was more potent in the carrageenan‐evoked hyperalgesia. LE‐EK06 (11.09 mg/kg, p.o.) and naproxen (8.0 mg/kg, p.o.) showed a comparable inhibitory effect on exudate formation and migration of polymorphonuclear leukocytes (PMNs) in a carrageenan‐induced pleurisy test. Further, the compound (11.09 mg/kg, p.o.) significantly reduced myeloperoxidase activity in carrageenan‐treated paw and demonstrated significantly less gastrotoxicity in acute and chronic (21 days) studies. The scanning electron microscopy revealed that LE‐EK06 showed only mild gastric damage (slight disruption of mucus layer) in comparison to naproxen. The present study suggested that naproxen‐2‐nitrooxyethylester (LE‐EK06) represents a novel gastric sparing NSAID. Drug Dev. Res. 61:66–78, 2004. © 2004 Wiley‐Liss, Inc. 相似文献
48.
P. M. Parikh S. H. Advani J. S. Nadkarni S. Kulkarni G. Kapoor P. S. R. K. Sastry M. Anand T. K. Saikia R. Gopal 《Cancer investigation》1997,15(4):326-328
Hepatic veno-occlusive disease (VOD) is the second most common cause of death after autologous bone marrow transplantation (ABMT). A patient with multiple myeloma undergoing ABMT developed classic features of hepatic VOD. He responded to treatment with pentoxiphyllin. Serum tumor necrosis factor (TNF) levels showed remarkable correlation with the severity of VOD and response to therapy. 相似文献
49.
50.
Kulkarni P 《JAMA》2000,284(12):1512; author reply 1512-1512; author reply 1513