全文获取类型
收费全文 | 1095篇 |
免费 | 36篇 |
国内免费 | 44篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 35篇 |
妇产科学 | 83篇 |
基础医学 | 169篇 |
口腔科学 | 15篇 |
临床医学 | 129篇 |
内科学 | 224篇 |
皮肤病学 | 5篇 |
神经病学 | 41篇 |
特种医学 | 224篇 |
外科学 | 46篇 |
综合类 | 11篇 |
预防医学 | 44篇 |
眼科学 | 4篇 |
药学 | 77篇 |
中国医学 | 2篇 |
肿瘤学 | 59篇 |
出版年
2022年 | 6篇 |
2019年 | 8篇 |
2018年 | 9篇 |
2015年 | 18篇 |
2014年 | 17篇 |
2013年 | 22篇 |
2012年 | 15篇 |
2011年 | 24篇 |
2010年 | 24篇 |
2009年 | 24篇 |
2008年 | 23篇 |
2007年 | 55篇 |
2006年 | 28篇 |
2005年 | 37篇 |
2004年 | 26篇 |
2003年 | 17篇 |
2002年 | 24篇 |
2001年 | 23篇 |
2000年 | 29篇 |
1999年 | 31篇 |
1998年 | 41篇 |
1997年 | 37篇 |
1996年 | 40篇 |
1995年 | 34篇 |
1994年 | 51篇 |
1993年 | 26篇 |
1992年 | 14篇 |
1991年 | 19篇 |
1990年 | 26篇 |
1989年 | 46篇 |
1988年 | 46篇 |
1987年 | 47篇 |
1986年 | 29篇 |
1985年 | 33篇 |
1984年 | 25篇 |
1983年 | 16篇 |
1982年 | 13篇 |
1981年 | 9篇 |
1980年 | 12篇 |
1979年 | 15篇 |
1978年 | 7篇 |
1977年 | 21篇 |
1976年 | 16篇 |
1975年 | 9篇 |
1974年 | 9篇 |
1971年 | 7篇 |
1969年 | 12篇 |
1968年 | 5篇 |
1967年 | 6篇 |
1966年 | 5篇 |
排序方式: 共有1175条查询结果,搜索用时 31 毫秒
61.
62.
Bulajić Velimirović S Kucera I Nikolić B Zecević R Mladenović T 《Vojnosanitetski pregled. Military-medical and pharmaceutical review》2000,57(2):187-190
Mycological findings of 2,447 skin specimens were analyzed. The aim of the study was to estimate the methodology for mycological examination, frequency of particular fungal species isolation and localization on the skin. Fungi were found in 591 specimens: 53.64% microscopically and isolated in cultures, 31.47% only microscopically and 14.89% only isolated in cultures. Total number of isolated strains was 405 (356 strains grew on Sabouraud agar with antibiotics and 272 on mycobiotic agar). The most frequently isolated species were: Trichophyton mentagrophytes (27.9%), Trichophyton rubrum (20%) and Candida albicans (9.14%). The most frequent localizations on skin where fungi had been found were foot (41.47%), toe-nail (22.06%) and finger-nail (10.88%). Sabouraud agar is more reliable for isolation of dermatophytes and mycobiotic agar for Candida species. Usage of both media for primoisolation provides better and faster identification of fungi causing dermatomycoses. Comparing our with other studies, the patterns of fungal appearance in our population had changed and the number of nail specimens, where fungi were found had increased. 相似文献
63.
DL DSouza SB Heinze RJ Dowling 《Journal of Medical Imaging and Radiation Oncology》2006,50(3):246-248
Lung cancer is not commonly known to metastasise to the perirenal space, with only five such cases previously published. We present an unusual case of perirenal lung metastases manifesting as diffuse perinephric stranding which to our knowledge has not been described before. 相似文献
64.
Ectopic pregnancy 总被引:13,自引:0,他引:13
Lehner R Kucera E Jirecek S Egarter C Husslein P 《Archives of gynecology and obstetrics》2000,263(3):87-92
Ectopic pregnancy is a implantation occurring elsewhere than in the cavity of the uterus, whereas nintynine percent of extrauterine
pregnancies occur in the fallopian tube. The incidence of extrauterine pregnancy has increased from 0.5% thirty years ago,
to a present day 1–2%. The most frequent cause of tubal pregnancy is previous salpingitis. Mortality rates for tubal pregnancies
used to be approximately 1.7% in the 1970 s but dropped to 0.3% in 1980 s. Diagnosis: Using transvaginal ultrasound it is possible to obtain positive evidence of an ectopic pregnancy at a very early stage. In
cases of hCG titers>2000 IU/l, intrauterine pregnancy can be diagnosed with certainty. The most important differential diagnosis
of ectopic pregnancy is early intrauterine pregnancy. Clinical management and therapy: Regardless of the therapeutic strategy selected by the physician, informing the patient is a major aspect of the management
of ectopic pregnancy. If surgery is considered appropriate, the patient must be informed about the nature, side effects and
complications of the procedure. However, it should be remembered that in some cases, the actual chances of cure first become
apparent at surgery. In asymptomatic patients with a serum hCG titer <1000 IU/l that is falling, it is appropriate to wait
and watch. In clinically stable patients with an unruptured tubal pregnancy and steady hCG levels, systemic treatment with
methotrexate might also be considered. In unruptured tubal pregnancy with a hCG titer between 1000 and 2500, a further therapeutic
alternative is intratubal injection of prostaglandins, hyperosmolar glucose of NaCl. Generally speaking, the currently widespread
laparoscopic surgical treatment of the fallopian tube hardly influences the risk of recurrence. If the gestational mass is
larger, the serum hCG titer higher than the approximate limit of 2500 mU/ml and/or the tube already ruptured, surgery is usually
required. Prevention: The most effective prevention is to avoid tubal inflammation or, in cases of preexisting inflammation, to administer effective
therapy.
Received: December 1998 / Accepted: 25 May 1999 相似文献
65.
66.
Brandon DL Marshall Thomas Kerr Chris Livingstone Kathy Li Julio SG Montaner Evan Wood 《Harm reduction journal》2008,5(1):35
Aboriginal people experience a disproportionate burden of HIV infection among the adult population in Canada; however, less
is known regarding the prevalence and characteristics of HIV positivity among drug-using and street-involved Aboriginal youth.
We examined HIV seroprevalence and risk factors among a cohort of 529 street-involved youth in Vancouver, Canada. At baseline,
15 (2.8%) were HIV positive, of whom 7 (46.7%) were Aboriginal. Aboriginal ethnicity was a significant correlate of HIV infection
(odds ratio = 2.87, 95%CI: 1.02 – 8.09). Of the HIV positive participants, 2 (28.6%) Aboriginals and 6 (75.0%) non-Aboriginals
reported injection drug use; furthermore, hepatitis C co-infection was significantly less common among Aboriginal participants
(p = 0.041). These findings suggest that factors other than injection drug use may promote HIV transmission among street-involved
Aboriginal youth, and provide further evidence that culturally appropriate and evidence-based interventions for HIV prevention
among Aboriginal young people are urgently required. 相似文献
67.
68.
Protein kinase C modulation and anticancer drug response 总被引:2,自引:0,他引:2
69.
In this report we describe results showing that both arachidonic acid (20:4) release and prostaglandin (PG) synthesis in herpes simplex virus type 2 (HSV-2)-transformed tumor-derived rat fibrosarcoma (RFS) cells are inhibited by indomethacin (cyclooxygenase inhibitor). These data suggest that cyclooxygenase (prostaglandin endoperoxide synthetase, PES) and phospholipase are coupled in their regulation in RFS cells. Data obtained using a cell-free assay to measure directly cyclooxygenase specific activity in the absence of phospholipase activity indicate that constitutive cyclooxygenase activity is very low in non-transformed REF and is not induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). In contrast, after an initial degradation of constitutive enzyme, cyclooxygenase is synthesized de novo following TPA treatment of HSV-2-transformed RFS clonal cells. At least a 5-fold induction of cyclooxygenase occurs by 6 h post-treatment of HSV-2-transformed RFS clonal cells. This induction is inhibited by pretreatment of cells with cycloheximide (protein synthesis inhibitor) 1 h prior to TPA treatment. Results obtained following delayed addition of cycloheximide to cells after TPA treatment indicate that the newly synthesized cyclooxygenase has a half-life of approximately 5 min. In addition, HSV-2-transformed RFS clonal cells at low passage (less than 10) show over a 3-fold greater increase in cyclooxygenase specific activity after TPA treatment compared to that in TPA-treated high passage (greater than 20) cells, suggesting that induction of high levels of PG synthesis is transient in these cells. These data indicate that HSV-2 transformation of REF cells is associated with alteration of cyclooxygenase regulation. 相似文献
70.
Age-related postural deficits elicit compensatory mechanisms such as ankle dorsiflexion in the elderly. To gain further insight into this problem, the ability to match an ankle angle during quiet stance was studied in 12 elderly and 12 young subjects. Following an initial single limb angular perturbation presented in the ±4° range, a subject had to return a tilt platform to level, as determined by the nonperturbed limb. Elderly subjects exhibited significant positive (0.9°) over-shoot of the level position, in contrast to young subjects who matched ankle angle with a mean error of −0.1°. The elderly group also exhibited an increase in positioning error for angular displacements in the range between −1 and +1°. The results document age-related postural changes in ankle positioning which might affect postural stability in older adults. 相似文献