全文获取类型
收费全文 | 17608篇 |
免费 | 1105篇 |
国内免费 | 330篇 |
专业分类
耳鼻咽喉 | 174篇 |
儿科学 | 375篇 |
妇产科学 | 404篇 |
基础医学 | 2092篇 |
口腔科学 | 432篇 |
临床医学 | 1913篇 |
内科学 | 3097篇 |
皮肤病学 | 545篇 |
神经病学 | 899篇 |
特种医学 | 838篇 |
外科学 | 2618篇 |
综合类 | 1262篇 |
现状与发展 | 1篇 |
一般理论 | 2篇 |
预防医学 | 925篇 |
眼科学 | 360篇 |
药学 | 1458篇 |
5篇 | |
中国医学 | 570篇 |
肿瘤学 | 1073篇 |
出版年
2023年 | 132篇 |
2022年 | 368篇 |
2021年 | 557篇 |
2020年 | 292篇 |
2019年 | 326篇 |
2018年 | 509篇 |
2017年 | 390篇 |
2016年 | 424篇 |
2015年 | 606篇 |
2014年 | 851篇 |
2013年 | 906篇 |
2012年 | 1406篇 |
2011年 | 1359篇 |
2010年 | 941篇 |
2009年 | 798篇 |
2008年 | 1103篇 |
2007年 | 1115篇 |
2006年 | 1009篇 |
2005年 | 965篇 |
2004年 | 803篇 |
2003年 | 636篇 |
2002年 | 591篇 |
2001年 | 513篇 |
2000年 | 451篇 |
1999年 | 346篇 |
1998年 | 133篇 |
1997年 | 98篇 |
1996年 | 95篇 |
1995年 | 72篇 |
1994年 | 69篇 |
1993年 | 38篇 |
1992年 | 124篇 |
1991年 | 111篇 |
1990年 | 104篇 |
1989年 | 68篇 |
1988年 | 59篇 |
1987年 | 68篇 |
1986年 | 56篇 |
1985年 | 55篇 |
1984年 | 35篇 |
1983年 | 24篇 |
1980年 | 26篇 |
1979年 | 31篇 |
1977年 | 30篇 |
1976年 | 25篇 |
1975年 | 26篇 |
1974年 | 28篇 |
1973年 | 26篇 |
1972年 | 30篇 |
1970年 | 23篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
11.
12.
J C Shih T L Ko M C Lin M K Shyu C N Lee F J Hsieh 《Ultrasound in obstetrics & gynecology》2004,24(2):202-206
The relationship of large and vascularized chorioangiomas to adverse pregnancy outcome is well recognized. We present a patient with a large placental tumor and signs of impending fetal cardiac failure. The angioarchitecture of the tumor depicted by three-dimensional (3D) power Doppler ultrasound enabled us to accurately diagnose a placental chorioangioma. During the follow-up period, quantitative flow data obtained using 3D power Doppler indicated altered hemodynamics in the tumor and concomitant improvement in the condition of the fetus, enabling us to manage the mother conservatively. Spontaneous delivery occurred at 38 weeks without any complications. This report demonstrates the potential value of 3D power Doppler in prenatal diagnosis and monitoring of pregnancies complicated by large, vascularized chorioangioma. 相似文献
13.
AIM: Benign childhood epilepsy with centro-temporal spikes (BCECTS) is the most common idiopathic partial epilepsy in children. Treatment attitudes remain a controversial issue. We examine features that could suggest refractoriness at onset. METHODS: We retrospectively reviewed the medical records of 144 children with BCECTS diagnosed at the Division of Pediatric Neurology, Asan Medical Center, from March 1, 1995, to April 30, 2002 and treated with AEDs. The patients were subdivided into two groups according to the number of antiepileptic drugs used for effective seizure control. RESULTS: Of the 144 patients, 75 were male and 69 were female, with a mean age at seizure-onset of 7.2 +/- 2.3 years (range, 2.1-14.3 years); 119 children were taking one antiepileptic drug (AED) (Group A), and 25 were taking more than one (Group B). There were no significant group differences in female-to-male ratio, prescribed AEDs, number of seizures before the start of treatment, interval between seizure-onset and start of treatment, presence of secondarily generalized seizures, or presence of bilateral EEG abnormalities. The groups differed however, in mean age at seizure onset (7.6 +/- 2.2 years versus 5.1 +/- 1.9 years, p < 0.05) and percentage of patients with seizure-onset before 3 years (p < 0.05). CONCLUSIONS: When treated with AEDs, children with BCECTS usually respond well. However, an earlier onset of seizures is associated with more frequent seizures and initial refractoriness to medical treatment. 相似文献
14.
S. Koëter C. J. M. van Loon J. L. C. van Susante 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2006,16(3):268-270
A lateral patella luxation is occasionally complicated by an (osteo)chondral fracture. These fractures are usually located at the inferomedial part of the patella. In this case report we describe an osteochondral fracture of the lateral femoral condyle after a dislocation of the patella. The latter is a more severe injury because it involves an important weight bearing part of the knee joint. Refixation of the osteochondral fracture should be pursued. Various surgical techniques using nonresorbable materials have been described. We describe the advantages and disadvantages of refixation with biodegradable pin fixation for an osteochondral fracture caused by a patellaluxation. 相似文献
15.
Ryo Hattori MD Tateki Kubo MD Kenji Yano MD PhD Atsushi Tanemura MD Yuji Yamaguchi MD PhD Satoshi Itami MD PhD Ko Hosokawa MD PhD 《Dermatologic surgery》2003,29(10):1071-1072
BACKGROUND: Nevus lipomatosus cutaneous superficialis (NLCS) is a relatively rare condition. Although NLCS can affect any region of the entire body, no case of NLCS in the clitoris has ever been reported. OBJECTIVE: To report a case of NLCS of the clitoris that presented manifestations that were similar to female pseudohermaphrodism. METHODS: This is a case report and review of the literature. RESULTS: A congenital, soft, skin-colored lesion of the clitoris in a 1-year-old girl resembled female pseudohermaphrodism. It was resected, and the histologic diagnosis was NLCS. Postoperatively, there was no subsequent change in the lesion during the 3-year follow-up period. CONCLUSION: We reported a case of congenital solitary NLCS of the clitoris. Although NLCS might be a relatively rare condition, we should consider it in the differential diagnosis of female pseudohermaphrodism. 相似文献
16.
T.-N. Wu Chen-Yang Shen Saou-Hsing Liou Guang-Yang Yang K.-N. Ko Show-Lin Chao Chao-Chun Hsu P.-Y. Chang 《International archives of occupational and environmental health》1997,69(6):386-391
To monitor the lead hazards in industries and to investigate the prevalence of elevated blood lead levels (BLLs) in lead-exposed
workers, a lead surveillance system (PRESS-BLLs) has been established and operated in Taiwan, Republic of China, since July
1993. A cohort of lead-exposed workers who received a periodic annual health examination at 55 accredited hospital laboratories
was constructed. A total of 9807 separate BLL measurements were reported to the system in 1994. The mean BLL was 15.8 μg/dl
in male workers and 11.6 μg/dl in female workers. The mean BLL of lead-exposed workers was significantly (P<0.05, z-test) higher than that of the general Taiwanese population (8.6 μg/dl for males and 6.7 μg/dl for females). In addition,
the BLLs of 983 (10.0%) workers exceeded the regulatory action level (40 μg/dl for males; 30 μg/dl for females). The workplaces
and homes of 57% of the workers with elevated BLLs were thoroughly investigated to determine the sources of lead contamination.
These actions identified the causes of elevated BLLs and set up strategies to reduce workers’ lead exposure. The establishment
of this occupational lead surveillance system represents a method for monitoring of lead hazards from occupational and environmental
settings to prevent lead poisoning. The information acquired from the system can help in the setting up of a priority of prevention
and the development of control measures. It is also useful for further monitoring of changes in the BLLs of the lead-exposed-worker
cohort. The Health Department of Taiwan can use this information to evaluate the effectiveness of current industrial hygiene
practice. Subjects with elevated BLLs have been medically treated and placed on long-term follow-up for sequelae.
Received: 2 September 1996/Accepted: 29 November 1996 相似文献
17.
Implantation of porcine bone morphogenetic protein (pBMP) in the muscle induces differentiation of mesenchymal-type cells and results in endochondral bone formation. pBMP was isolated from porcine demineralized bone matrix and purified by hydroxyapatite chromatography, Sephadex G75 gel filtration, preparative sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), preparative isoelectric focusing (IEF), and chromatofocusing fast protein liquid chromatography (FPLC). Porcine BMP has an MW of 26 K and a range of pI from 4.65 to 4.73 determined by SDS-PAGE and IEF, respectively. Reconstitution with the citrate buffer supernatant fraction enables as little as 50 micrograms of the soluble pBMP fractions to induce osteogenesis in an in vivo assay. Chemical modification studies indicate that the osteoinductive potential of the pBMP molecule depends on tyrosine, carboxyl groups, and disulfide bonds and can be increased by modification of sulfhydryl groups. Modification of arginine and tryptophan has no effect on bioactivity. By pepsin-limited proteolysis, fragments of pBMP with an MW of 6-14 K show definite, although reduced, BMP activity. 相似文献
18.
A 40-year-old woman had persistent Zollinger-Ellison syndrome despite excision of a 4-cm duodenal gastrinoma. Localizing studies including ultrasonography, computed tomography, magnetic resonance imaging, duodenal endoscopy, endoscopic ultrasonography, and intraoperative endoscopic transillumination of the duodenum failed to detect a tumor. Selective intra-arterial methylene blue injection was used to identify a 6-mm gastrinoma in the duodenum, which was locally excised. Postoperatively, the patient had a negative secretin provocative test result. This novel method uses selective arterial secretin injection with hepatic venous gastrin sampling to identify the vessel feeding the gastrinoma. An angiographic catheter is then positioned in this artery. At laparotomy, methylene blue is injected through this catheter to selectively stain the gastrinoma, facilitating its identification. Selective intra-arterial methylene blue injection can enhance intraoperative detection of small gastrinomas and may improve the rate of curative resection in the Zollinger-Ellison syndrome. Further evaluation of this novel localizing technique is warranted. 相似文献
19.
A finite element analysis was carried out to study the roles of posts in reducing dentin stress in pulpless teeth. Two-dimensional plane strain models of the midlabiolingual section of a human maxillary central incisor were first analyzed. The results showed that the gold alloy post reduced maximal dentin stress by as much as 30%. However, the integrity of the dentin was compromised and the effects of the post were likely to be exaggerated in such models. In an effort to correct for these problems, plane stress models with side plates and axisymmetric models were analyzed. Posts were found to reduce maximal dentin stress by only 3% to 8% when the teeth were subjected to masticatory and traumatic loadings in these latter models. Although posts reduced maximal dentin stress by as much as 20% when the teeth were loaded vertically, teeth such as incisors and canines normally are not subjected to vertical loadings. Thus the reinforcement effects of posts seem to be doubtful in these teeth. 相似文献
20.
T M Ko C Y Hsieh H N Ho F J Hsieh T Y Lee 《American journal of obstetrics and gynecology》1991,164(3):901-906
To determine the genetic origin of the complete hydatidiform mole, 20 abnormal pregnancies were studied with restriction fragment length polymorphism with five genomic probes: EJ 6.6, beta-globin gene, 3'alpha-hypervariable region, J-Bir, and St14. In the 12 cases of molar pregnancy, pure paternal origin was proved in 11 cases, but both maternal and paternal inheritance were shown in only one case. In the cases with pure paternal origin, all of the restriction fragment length polymorphisms were homozygous, although those of the fathers were heterozygous at 15 loci. In the four cases that mimicked hydatidiform mole but were diagnosed as hydropic change of villi, both paternal and maternal inheritance were noted. In the four pregnancies with blighted ovum, both paternal and maternal inheritance were shown in three cases; and in one case with a balanced translocation between chromosomes 13 and 14, only paternal inheritance was noted. This study showed that most of the complete hydatidiform moles were caused by fertilization of an empty egg by a duplicated haploid sperm, but rare exceptions may exist. 相似文献