Medium term follow-up of a randomized controlled trial of interventions for young people at ultra high risk of psychosis

Valid criteria to identify young people who are believed to be at ultra high risk (UHR) of developing a psychotic episode were developed over the last decade. The first randomized controlled trial of treatment in a UHR cohort indicated that specific pharmacotherapy and psychotherapy delayed onset of disorder, and possibly reduced incidence. This paper reports results of follow-up of that trial. 41 of the 59 (69.5%) participants in the original study agreed to follow-up. No differences were found in transition rate, level of symptomatology or functioning between participants who received a combination of psychological treatment and anti-psychotic medication compared to those who received supportive therapy alone. A significant proportion of both treatment groups reported moderate levels of psychiatric morbidity and a continuing need and desire for care at this follow-up. Low levels of hospitalisation were noted for those who did progress to psychosis. Conclusions that can be drawn from this exploratory study are limited by the relatively small number of participants in the original study and the failure to follow-up the entire cohort. Although participants may have been treated too briefly to result in enduring positive effects, there appear to have been some cost savings in inpatient mental health treatment required after the end of the trial for individuals in both treatment groups who developed psychosis.     

Self-Weighing and Weight Control Behaviors Among Adolescents with a History of Overweight

PurposeTo assess the relationships between self-weighing frequency, weight control behaviors, and weight status among male and female adolescents who have a history of being overweight.MethodsThis study compared weight control behaviors between two groups of adolescents with a history of being overweight (body mass index [BMI] >85th percentile): those who weighed themselves weekly or more (frequent self-weighers) and those who weighed themselves monthly or less (infrequent self-weighers). Participants completed a survey on weight control behaviors, dietary intake, physical activity, and sedentary activity. Height and weight were also measured. Logistic regression analyses were used for categorical outcomes and linear regressions for continuous outcomes.ResultsOf the 130 adolescents, 43% were frequent weighers and 57% were infrequent weighers. In comparison to infrequent self-weighers, frequent self-weighers were more likely to report using behavior change strategies, following a structured diet, and engaging in healthy weight control behaviors, especially decreasing caloric intake, high fat food intake, and “junk food” intake. Also, more frequent self-weighers reported engaging in more strenuous physical activity and spending less time playing videogames than infrequent self-weighers. Although not significant, a trend resulted indicating lower average BMI percentile among frequent self-weighers. No significant differences were found between the two groups in unhealthy weight control behaviors.ConclusionsThese results suggest that adolescents with a history of overweight who self-weigh at least weekly are more likely to report using healthy weight control behaviors than adolescents who self-weigh monthly or less frequently. Self-monitoring of weight may be a useful component of a comprehensive weight management plan for some overweight adolescents.     

Improving quality of care for urban older people with diabetes mellitus and cardiovascular disease

The management of older patients with chronic medical conditions dominates medical practice. Cardiovascular disease (CVD) and diabetes mellitus type 2 (DM) in patients aged 65 and older have reached epidemic proportions. Using elements of the Chronic Care Model (CCM), a quality improvement project was undertaken to restructure the Geriatric Ambulatory Practice at Boston Medical Center, Boston's safety net hospital, to improve the quality of care for CVD and diabetes mellitus. Two hundred eighty-three eligible patients who had CVD, DM, or both were identified. The 39-month project period was divided into a 12-month baseline period and three follow-up periods. The multifaceted intervention consisted of development of a disease registry that centralized clinical information, implementation of an electronic medical record, patient education, physician education regarding evidence-based guidelines, feedback of provider-specific and practice data to physicians, and implementation of a foot examination protocol. Clinical measures included glycosylated hemoglobin, a diabetic foot examination, lipid profile, and blood pressure measurement. These were collected at baseline and at each patient visit for the entire project period. The average age of all patients was 76; 64% were female, 64% were African American, 72% had Medicare, and 22% had state subsidized medical insurance. Patients in all disease groups showed significant improvement in all clinical measures over time, independent of the frequency of visits. Using the CCM as a quality improvement framework can improve clinical measures for older urban minority populations with CVD and DM.     

Management of hernias in pregnancy

BACKGROUND: Even though groin and umbilical hernias are rare in adult women, the rarer cases of pregnant women presenting with hernias create distinct challenges to treatment planning. The course of hernias in pregnant women, the effect of hernias on delivery, and the timing of elective herniorrhaphy have not been established. To date, there have been no published series establishing that postpartum repair of umbilical and groin hernias that develop in pregnancy is safe and acceptable. STUDY DESIGN: From September 2004 to July 2006, 12 female patients with groin or umbilical hernias occurring during pregnancy presented to a single surgeon at the Mount Sinai Medical Center. All patients later underwent postpartum herniorrhaphy and were enrolled retrospectively. All patients underwent either open umbilical or inguinal hernia repair primarily or using a plug-and-patch method (Bard Mesh PerFix Plug; Davol) in an ambulatory setting. Mean longterm followup was 17 months. RESULTS: Mean age of the patients was 35 years (range 27 to 41 years). The most common type of hernia was inguinal (58%). The predominant side was right (86%). None of the patients had an associated diagnosis or clinically significant medical history. All patients were evaluated, operated, and followed up by the same surgeon. Neither incarceration nor strangulation occurred in any patient before or after delivery. None required hospitalization or emergent hernia repair. Patients did not experience any delivery complications. All patients underwent elective postpartum open hernia repair with sedation and local anesthesia (4 to 52 weeks postpartum; mean 22 weeks postpartum). No patient experienced any perioperative or postoperative complications. None of the patients experienced a hernia recurrence. Four patients had subsequent uncomplicated pregnancies. CONCLUSIONS: This series lends support to the "watchful waiting" strategy during pregnancy, with a plan for postpartum herniorrhaphy. Elective, postpartum hernia repair provides similar results to the nonpregnant population.     

The hospital-based adoption process: a primer for perinatal nurses

Although the number of women who relinquish their infants is declining, it is estimated that over 52,000 young women pursue an adoption plan every year. Perinatal nurses practicing in any facet of perinatal care may provide care for a woman implementing an adoption plan for her infant. The provision of care may include interaction with the birthfather, prospective adoptive parents, hospital social worker, and adoption agency or adoption attorney as part of the hospital-based adoption experience. Understanding infant adoption, including the history of adoption in the United States, birthfathers' rights, and knowledge of adoption resources provides nurses with essential information that will allow them to provide appropriate, sensitive, nonjudgmental care to all persons involved in the adoption process.