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Basudha Shrestha Tatsuya Tada Tohru Miyoshi-Akiyama Kayo Shimada Hiroshi Ohara Teruo Kirikae Bharat M. Pokhrel 《Antimicrobial agents and chemotherapy》2015,59(9):5847-5850
A novel New Delhi metallo-β-lactamase, NDM-13, was identified in a carbapenem-resistant Escherichia coli clinical isolate obtained from the urine of a patient in Nepal. The enzymatic activity of NDM-13 against β-lactams was similar to that of NDM-1. However, NDM-13 displayed significantly higher kcat/Km ratios for cefotaxime. The genetic environment of blaNDM-13 was determined to be tnpA-IS30-blaNDM-13-bleMBL-trpF-dsbC-cutA-groES-groL, with blaNDM-13 located within the chromosome. 相似文献
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Expression of AKR1C3 and CNN3 as markers for detection of lymph node metastases in colorectal cancer
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Tomoko Noma Mai Kabayama Yasuyuki Gondo Saori Yasumoto Yukie Masui Ken Sugimoto Hiroshi Akasaka Kayo Godai Atsuko Higuchi Yuya Akagi Yoichi Takami Yasushi Takeya Koichi Yamamoto Kazunori Ikebe Yasumichi Arai Tatsuro Ishizaki Hiromi Rakugi Kei Kamide 《Geriatrics & Gerontology International》2020,20(7):720-726
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The study investigated age-related changes in the thickness of the deep and superficial abdominal muscles of 103 healthy women who could walk independently The participants were classified into five age groups: young (n=26; 20-24 years), young adult (n=26; 25-44 years), middle-aged (n=16; 45-64 years), young-old (n=16; 65-74 years), and old-old (n=19; 75-85 years). The muscle thicknesses of the right rectus abdominis, external oblique, internal oblique, and transversus abdominis were measured using ultrasound imaging. The rectus abdominis was significantly thicker in the young group compared with the young adult, middle-aged, young-old, and old-old groups (p<0.05). The external oblique and internal oblique muscles were significantly thicker in the young group compared with the middle-aged, young-old, and old-old groups (p<0.05). However, there were no significant differences in the thickness of the transversus abdominis between groups. The results suggest that age-related muscle atrophy occurs from an early age in superficial abdominal muscles, such as rectus abdominis, and that age-related atrophy is less in deep abdominal muscles such as the transversus abdominis. 相似文献
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