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991.
Katherine Wiegmann Shylaja Muthyala Duk Hwan Kim Barry G. W. Arnason Ewa Chelmicka-Schorr 《Journal of neuroimmunology》1995,56(2)
Chronic/relapsing experimental allergic encephalomyelitis (CREAE) serves as an animal model for relapsing/remitting multiple sclerosis. Treatment with the β-adrenergic agonist isoproterenol or the β2-adrenergic agonist terbutaline significantly suppressed both the first acute attack and the number of relapses in CREAE Lewis rats. The number of relapses was decreased even when treatment with β-adrenergic agonist was started after the onset of the first acute attack of CREAE. β-adrenergic receptor number was increased significantly on splenocytes from CREAE rats as compared to healthy controls or CFA-injected rats. Terbutaline treatment of CREAE rats lowered the splenocyte receptor number to normal values. 相似文献
992.
数字减影在经内镜胆管内取石术中的应用(附30例分析) 总被引:2,自引:0,他引:2
数字减影具有分辨率高、实时成像的特点,为经内镜胆管内结石顺利操作提供了方便。本文总结30例用数字减影胆管内取石,认为术前病人应充分肠道准备,合理使用平滑肌松弛剂,术中多角度观察,ERCP复查,可望明显提高手术成功率。 相似文献
993.
D. G. Kim C.-Y. Kim S. H. Paek D. S. Lee J.-K. Chung H.-W. Jung B.-K. Cho 《Acta neurochirurgica》1998,140(7):665-674
Summary
Background To determine its roles in the diagnosis and the systemic evaluation of metastatic brain tumours, whole-body positron emission
tomography (PET) using [18F]FDG was performed in 20 consecutive patients.
Methods
All patients were thought to be suffering or needing to be differentiated from metastatic brain tumours. Nine patients had
multiple brain lesions; six were older and showed a rim-enhancing lesion with surrounding oedema; seven had homogeneously
enhancing periventricular lesion(s) on computed tomography (CT) and/or magnetic resonance (MR) imaging, thought to be central
nervous system lymphomas. Two patients had skull mass(es) and two patients had a solid mass suspected to be, respectively,
a haemorrhagic metastasis and a metastatic malignant melanoma. All of them received whole-body [18F]FDG PET and conventional systemic work-up for metastasis in order to compare the results of the two methods.
Results
Metastatic brain tumours were diagnosed on whole-body [18F]FDG PET in eleven patients who had extracranial and intracranial hypermetabolic lesions. In nine of these, a conventional
work-up also detected primary lesions which on whole-body [18F]FDG PET were seen to be hypermetabolic foci. Systemic lymph node metastases were detected by whole-body [18F]FDG PET only in two patients and histological diagnosis was possible by biopsy of lymph nodes rather than of brain lesions.
In the remaining nine patients who had only intracranial hypermetabolic foci, histological diagnosis was made by craniotomy
or stereotactic biopsy. It was confirmed that seven of nine patients were suffering from a primary brain tumour and two from
metastatic carcinoma. None of the nine showed evidence of systemic cancer on conventional work-up. Histological diagnoses
of the primary brain tumours were four cases of primary central nervous system lymphoma and one each of multifocal glioblastoma,
Ewing's sarcoma, and cavernous angioma.
Patients felt no discomfort during the whole-body [18F]FDG PET procedure and there were no complications. The false negative rate in [18F]FDG PET and in conventional work-up was 15.4% and 30.7% respectively. There were no false positives on either [18F]FDG PET or conventional work-up.
Conclusion
It is suggested that whole-body [18F]FDG PET is a safe, reliable, and convenient method for the diagnosis and systemic evaluation of patients thought to be suffering
or needing to be differentiated from a metastatic brain tumour. 相似文献
994.
207例预激综合征的心律失常 总被引:1,自引:0,他引:1
对207例预激综合征行电生理检查.检出心律失常171例.占82.6%。房室折返性心动过速占所有心律失常的80.4%,心房颤动13.1%,其他6.5%.房室折返性心动过速占我院同期室上速的56.5%.远较房室结折返性心动过速(24.4%)多见。隐性旁路在室上速中占29%,居首位。上述情况反映我国人室上速的构成比可能与西方国家不同。 相似文献
995.
A new cycloartane glycoside (1) was isolated from the aerial part ofThalictrum uchiyamai Nakai (Ranunculaceae). On the basis of chemical and physicochemical evidence, the aglycone structure of this compound was characterized as 16,25-dihydroxy-3,24-diacetoxy-9, 19-cycloartane-29-oic acid, a new derivative of cycloartane triterpene. Also, the oligosaccharide moiety of this glycoside were determined as 29-O-α-L-rhanmnopyranosyl-(1→2)-[β-D-xylofuranosyl-(1→6)]-β-D-glucopyranosy by application of HMBC technique. Consequently, the structure of compound 1 was elucidated as 29-O-α-L-rhanmnopyranosyl-(1→2)-[β-D-xylofuranosyl-(1→6)]-β-D-glucopyranosyl-16, 25-dihydroxy-3,24-diacetoxy-9,19-cycloartane-29-oic acid ester. 相似文献
996.
997.
998.
Protective Effect of Salvia Miltiorrhizae Composita on Myocardium in Patients Undergoing Open Heart Surgery
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Protective Effect of Salvia Miltiorrhizae Composita on Myocardium in Patients Undergoing Open Heart Surgery@顾家珍@李俊@刘世清@张红艳@余金甫@夏正远 相似文献
999.
In order to find out anti-platelet activating factor (PAF) from natural resources, Korean medicinal plants used for the treatments
of peripheral circulation disorders were tested for their possible protective effects on PAF-induced anaphylactic shock. From
the above screening, the methanol extract ofGentiana scabra showed a potent antagonistic activity against PAF. Water suspension of the extract was partitioned with CH2Cl2 and EtOAc, successively. The EtOAc fraction which showed the highest activity was chromatographed on silica gel to yield
6 fractions. From the fraction which showed higher PAF-antagonistic activity than the other fractions, compound1 was isolated by recrystallization. On the basis of spectral data, compound1 was identified as 2-hydroxy-3-methoxybenzoic acid glucose ester. The compound prevented the mice from the PAF-induced death
at a dose of 300 μg/mouse. 相似文献
1000.
表浅性膀胱肿瘤的预后 总被引:6,自引:2,他引:4
从1980年1月至1991年12月,对121例表浅性膀胱肿瘤进行回顾性研究,首次手术采用经尿道肿瘤电灼术,电切术或膀胱部分切除术,术后配合膀胱内灌药辅助治疗。其中60例术后复发(49.6%),术后1、2、3和5年的无瘤率分别为86.8%、76.8%、73.5%和68.6%。资料表明,初诊时呈多发者、直径大于1cm和细胞恶性分级高的肿瘤术后无瘤率分别低于单发者、直径小于1cm和细胞恶性分级低的肿瘤,有显著性差异(P<0.05)。术后6个月内肿瘤复发者经治疗后肿瘤再次复发的机会高。术后膀胱内灌药可以预防肿瘤复发,以灌注丝裂霉素和卡介苗效果好。 相似文献