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971.
Ioannis Alexiou Anastasios Germenis Athanasios Ziogas Katerina Theodoridou Lazaros I Sakkas 《BMC musculoskeletal disorders》2007,8(1):37
Background
Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been of diagnostic value in Northern European Caucasian patients with rheumatoid arthritis (RA). In these populations, anti-CCP antibodies are associated with the HLA-DRB1 shared epitope. We assessed the diagnostic value of anti-CCP antibodies in Greek patients with RA where the HLA shared epitope was reported in a minority of patients. 相似文献972.
Background
Influenza and pneumococcal vaccination are recommended for a number of clinical risk groups including patients treated with major immunosuppressant disease modifying anti-rheumatic drugs. Such immunisation is not only safe but immunogenic in patients with rheumatic diseases. We sought to establish dual vaccination rates and significant influencing factors amongst our hospital rheumatology outpatients. 相似文献973.
Q M Van Dellen K Stronks P J E Bindels F G Ory J Bruil W M C Van Aalderen 《The Journal of asthma》2007,44(2):125-131
This study aimed to identify and explain differences in health-related quality of life (QoL) between immigrant and non-immigrant children with asthma. In 274 children (7-17 years of age) generic and asthma-related QoL were assessed. The association between ethnicity and QoL was studied in linear regression model analyses. For the asthma-related QoL, unadjusted analyses showed significant ethnic differences. The non-immigrant children had the highest scores, which implies a better QoL. After adjusting for asthma control and socioeconomic status (SES), ethnic differences disappeared. These results suggest that immigrant children have a similar QoL to that of non-immigrant children from a comparable SES, when their asthma is under control. 相似文献
974.
Nobuhito Morota 《Child's nervous system》2007,23(9):1007-1014
Purpose The author describes the history of functional posterior rhizotomy (FPR), the surgical procedure currently used, and the results
together with its future perspective in Japan. The modern form of FPR was introduced to Japan in 1995, and the first surgery
was carried out in 1996. Despite initial resistance from orthopedic surgeons, the procedure has eventually gained wide recognition
in the country.
Materials and Methods The author has operated on 98 patients (60 boys and 38 girls, aged from 2 to 19 years old) by the end of 2006. Most patients
were mild to severely disabled children with spastic hypertonia because of cerebral palsy and other diseases. The surgical
procedure used is based on the Peacock’s procedure with some modification for the mildly disabled children whose spasticity
was predominantly the muscles of the ankle joint. Intraoperative neurophysiology was an indispensable tool for preserving
urogenital function and for judging which root/rootlet to be cut.
Results Seventeen to 83% of the root/rootlets were found to be abnormal and were cut, clearly correlating with the degree of disability.
However, there was a wide difference in the cutting rate, even in children with the same degree of disability. The result
of surgery in this group of patients was the same as in previously published data. Twenty out of 51 patients (39%) followed
for more than a year at the current institute showed improved locomotion after FPR. Thirty patients (59%) demonstrated suprasegmental
effects after FPR.
Conclusion The role of FPR will grow in importance as a treatment for spasticity in Japan in the future. 相似文献
975.
Kuniaki Nakahara Satoru Shimizu Satoshi Utsuki Sachio Suzuki Hidehiro Oka Kiyotaka Fujii 《Child's nervous system》2007,23(8):863-865
Objects We evaluated whether the presence of lacunar skull deformity (LSD) with myelomeningocele is a predictive factor for subsequent
hydrocephalus development.
Materials and methods We reviewed the clinical and radiological records of 18 infants with myelomeningocele, divided the patients into groups with
(group A, n=9) and without (group B, n=9) ventriculomegaly at birth and assessed whether the presence of LSD was predictive of the necessity for ventriculoperitoneal
shunt (VPS) placement.
Results LSD was present in five group A patients. All nine group A patients underwent VPS placement. Among the group B patients, five
had LSD; they underwent VPS placement. A significantly higher proportion of those with ventricle enlargement or LSD at birth
required VPS placement (p=0.0001).
Conclusion Adding to the ventriculomegaly at birth, the presence of LSD alerts to the necessity to monitor these infants closely to determine
the necessity for VPS placement. 相似文献
976.
977.
978.
Paolo Miletto 《European journal of nuclear medicine and molecular imaging》2007,34(2):304-304
979.
AP de Moraes† ÉÂG de Arruda† MAV Vitoriano† MO de Moraes Filho‡ FÂF Bezerra‡ E de Magalhães Holanda§ MEA de Moraes‡ 《Journal of the European Academy of Dermatology and Venereology》2007,21(5):596-601
BACKGROUND: Seborrhoeic dermatitis (SD) is a common dermatosis in human immunodeficiency virus (HIV)-positive patients, many of whom do not respond satisfactorily to conventional topical treatments such as corticosteroids and antifungals. OBJECTIVE: A pilot study to investigate the efficacy and tolerability of pimecrolimus cream 1% in HIV-positive patients with facial SD. METHODS: In a single-centre study, 21 HIV-infected patients with mild to severe SD were treated twice daily with pimecrolimus cream 1% for 14 days. Thereafter, treatment was discontinued and patients followed up for 5 weeks. Skin involvement at baseline and on days 7, 14, 21, 35 and 49 was assessed using a four-point clinical score and digital photography. MAIN OUTCOME MEASURES: Efficacy and safety of pimecrolimus cream 1% treatment and incidence of relapse in the follow-up phase. Results Marked improvement was seen in clinical parameters at day 7, with >or= 90% patients clear of symptoms at day 14. Relapse was observed at day 35 but signs were milder than at baseline. All patients responded to therapy, despite their immunological status. Pimecrolimus did not alter CD4(+) and CD8(+) T-cell counts or viral load during the treatment period. CONCLUSION: Pimecrolimus cream represents a new, effective therapeutic option for facial SD in HIV patients. 相似文献
980.
James A. Case Bai Ling Hsu Timothy M. Bateman S. James Cullom 《Journal of nuclear cardiology》2007,14(3):324-333
Background High-quality attenuation maps are critical for attenuation correction of myocardial perfusion single photon emission computed
tomography studies. The filtered backprojection (FBP) approach can introduce errors, especially with low-count transmission
data. We present a new method for attenuation map reconstruction and examine its performance in phantom and patient data.
Methods and Results The Bayesian iterative transmission gradient algorithm incorporates a spatially varying gamma prior function that preferentially
weights estimated attenuation coefficients toward the soft-tissue value while allowing data-driven solutions for lung and
bone regions. The performance with attenuation-corrected technetium 99m sestamibi clinical images was evaluated in phantom
studies and in 50 low-likelihood patients grouped by body mass index (BMI). The algorithm converged in 15 iterations in the
phantom studies. For the clinical studies, soft-tissue estimates had significantly greater uniformity of mediastinal coefficients
(mean SD, 0.005 cm−1 vs 0.011 cm−1; P<.0001). The accuracy and uniformity of the Bayesian iterative transmission gradient algorithm were independent of BMI, whereas
both declined at higher BMI values with FBP. Attenuation-corrected perfusion images showed improvement in myocardial wall
variability (4.8% to 4.1%, P=.02) for all BMI groups with the new method compared with FBP.
Conclusion This new method for attenuation map reconstruction provides rapidly converging and accurate attenuation maps over a wide spectrum
of patient BMI values and significantly improves attenuation-corrected perfusion images. 相似文献