全文获取类型
收费全文 | 44266篇 |
免费 | 2175篇 |
国内免费 | 118篇 |
专业分类
耳鼻咽喉 | 611篇 |
儿科学 | 852篇 |
妇产科学 | 858篇 |
基础医学 | 5630篇 |
口腔科学 | 2162篇 |
临床医学 | 3333篇 |
内科学 | 11366篇 |
皮肤病学 | 838篇 |
神经病学 | 3658篇 |
特种医学 | 814篇 |
外科学 | 5693篇 |
综合类 | 234篇 |
一般理论 | 16篇 |
预防医学 | 3963篇 |
眼科学 | 944篇 |
药学 | 3084篇 |
中国医学 | 182篇 |
肿瘤学 | 2321篇 |
出版年
2024年 | 30篇 |
2023年 | 288篇 |
2022年 | 212篇 |
2021年 | 855篇 |
2020年 | 463篇 |
2019年 | 963篇 |
2018年 | 1735篇 |
2017年 | 1085篇 |
2016年 | 1075篇 |
2015年 | 1340篇 |
2014年 | 1455篇 |
2013年 | 2098篇 |
2012年 | 4052篇 |
2011年 | 4124篇 |
2010年 | 2135篇 |
2009年 | 1531篇 |
2008年 | 3421篇 |
2007年 | 3507篇 |
2006年 | 3363篇 |
2005年 | 3264篇 |
2004年 | 2854篇 |
2003年 | 2591篇 |
2002年 | 2401篇 |
2001年 | 148篇 |
2000年 | 129篇 |
1999年 | 144篇 |
1998年 | 118篇 |
1997年 | 97篇 |
1996年 | 102篇 |
1995年 | 88篇 |
1994年 | 75篇 |
1993年 | 72篇 |
1992年 | 61篇 |
1991年 | 61篇 |
1990年 | 31篇 |
1989年 | 37篇 |
1988年 | 22篇 |
1987年 | 23篇 |
1986年 | 25篇 |
1985年 | 32篇 |
1984年 | 43篇 |
1983年 | 28篇 |
1982年 | 48篇 |
1981年 | 31篇 |
1980年 | 41篇 |
1979年 | 12篇 |
1978年 | 14篇 |
1976年 | 12篇 |
1975年 | 16篇 |
1974年 | 21篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
Auke J. S. Renard Ren P. H. Veth Maciej Pruszczynksi Jaap Hoogenhout Jos Bkkerink Frans J. M. Van Der Staak Theo Wobbes Josef A. M. Lemmens Ren van Hoesel Jim R. Van Horn 《Journal of surgical oncology》1995,60(4):250-256
This paper describes 29 patients with Ewing's sarcoma of bone treated between 1975 and 1990 at the University of Nijmegen Hospital, Nijmegen, The Netherlands. Osteomyelitis was the primary diagnosis in 24%. Treatment consisted of chemotherapy in combination with surgery and/or radiotherapy. Nine patients received radiotherapy only; five of them died of disease. Five patients underwent an intralesional excision; four of them died of disease. Twelve patients underwent a wide excision; there is no evidence of disease in any of them. Three patients underwent a radical disarticulation; all died of disease. The disease-free survival at 1.5 years was 66%. This figure at 5 years was 55%. After wide excision and reconstruction in tumors of expendable, femoral or radial bones good functional results were obtained in all cases. © 1995 Wiley-Liss, Inc. 相似文献
72.
73.
Laurent Garel Josée Dubois Fran?oise Rypens Alain Ouimet Salam Yazbeck 《Journal l'Association canadienne des radiologistes》2004,55(1):39-44
OBJECTIVE: To report on the high incidence of anatomical variants of the origin and course of the internal spermatic vein (ISV) discovered at the time of percutaneous embolization of left varicoceles in a pediatric population. METHODS: We reviewed retrospectively the 65 cases of left varicocele treated by percutaneous embolization (grade II and III) in our institution between 1990 and 2000. The course of the left renal vein (LRV), the origin of the ISV, and the number of ISVs and their pathway were recorded in all cases, according to the B?hren classification. RESULTS: In 37/65 (57%), the ISV was single and arose from a normal LRV (type I). The following variants were encountered: type V--circumaortic LRV 9/65 (14%); type IVb--intrarenal origin of ISV 8/65 (12%); type II--multiple ISV 5/65 (8%); and pelvic collaterals 6/65 (9%). CONCLUSION: Venous anatomical variants are frequently encountered (43%) at the time of left varicocele embolization in children. Such variants often impose some adjustments to the technique of embolization and, at times, hamper the procedure. 相似文献
74.
Association of HLA-DQA1*03011-DQB1*0301 haplotype with the development of respiratory scleroma. 总被引:1,自引:0,他引:1
Luis Alberto Sánchez-Marín Daniel Bross-Soriano José Arrieta Simón Kawa-Karasik Víctor Martínez-Vilchis Rocío Jiménez-Lucio Angélica Olivo-Díaz 《Otolaryngology--head and neck surgery》2007,136(3):481-483
OBJECTIVE: Respiratory scleroma (RS) is a progressive, chronic, granulomatous disease caused by Klebsiella rhinoscleromatis. There is only one report of RS association with HLA-DQ3. In this study, molecular association of HLA class II and RS was determined. STUDY DESIGN AND SETTING: Nine RS patients and 163 healthy controls were compared. DQA1, DQB1, and DRB1 loci were typed. RESULTS: Statistical analysis demonstrated association between DQB1*0301 and susceptibility to RS (P(c) = 0.004). Haplotype analysis showed an association of DQA1*03011-DQB1*0301 (P = 1.21E-19) and DRB1*0407-DQA1*03011-DQB1*0301 (P = 0.0002). CONCLUSIONS: Results established that DQA1*03011-DQB1*0301 haplotype is a strong risk factor for development of RS. 相似文献
75.
76.
77.
In the past decade, several studies have used scaling and clustering techniques to document semantic storage deficits in patients with Alzheimer's disease and in schizophrenia. In this article the authors argued that many of the conclusions drawn from these studies are unjustified by the data. They reviewed the methodology used in these studies and presented data from simulation studies to further investigate the validity of their conclusions. The authors elaborate on the criteria needed to exclude alternative accounts of the data and present empirical data from patients with Alzheimer's disease and normal control participants to demonstrate that analyses of the patients' proximity data do not provide unambiguous evidence for a generalized semantic storage deficit. 相似文献
78.
The DNA breakage detection-fluorescence in situ hybridization (DBD-FISH) procedure was used to analyze DNA single-strand breaks (SSBs) and alkali-labile sites induced by exposure to the nitric oxide (NO) donors sodium nitroprusside (SNP) and 3-morpholinosydnomine hydrochloride (SIN-1) in the whole genome and in long interstitial telomeric repeat sequence (ITRS) blocks from Chinese hamster cells. The relative density of DNA damage generated in the ITRS by X-rays was similar to that induced in the genome overall, whereas it was 1.7 times higher when the alkylating agent MNNG was assayed. Nevertheless, after SNP or SIN-1 treatment, ITRSs proved to be 2.8 and 2.7 times relatively more damaged, respectively, than the whole genome. When the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) was not active, as in XR-C1 mutant cells, the repair kinetics in the whole genome did not differ from that in the parental cell line with X-ray or SNP exposure. However, whereas the SSBs and alkali-labile sites induced in the ITRS by X-rays exhibited rejoining kinetics similar to that of the parental cell line, the damage induced by SNP was more slowly rejoined. This implies a role for DNA-PKcs in the repair of DNA damage induced by NO, especially in ITRSs. The results demonstrated intragenomic heterogeneity of NO-induced DNA damage and repair; there was a higher density of DNA damage in the ITRS blocks, possibly because of their guanine richness. This suggests that a parallel process may occur in the terminal telomeres, which has implications for premature aging and neoplastic development by chronic NO exposure in vivo. 相似文献
79.
80.
Isabelle Knott Marc Dieu Maggi Burton Véronique Lecomte José Remacle Martine Raes 《Inflammation research》1993,39(3-4):126-131
The effects of interleukin-1 and were tested on the [3H]-arachidonic acid release and the prostaglandin synthesis by human cultured synovial cells and chondrocytes. Both forms of interleukin-1 stimulated the arachidonic acid release but interleukin-1 was more potent than IL-1. Human synovial cells and chondrocytes synthesized three types of prostaglandins upon stimulation with interleukin-1 or : prostaglandin E2, F2 and 6-keto-prostaglandin F1. Regarding the synthesis of these prostaglandins, IL-1 was again more potent than IL-1. A comparison between interleukin-1-stimulated synovial cells and chondrocytes revealed neither significant quantitative nor qualitative differences in both the arachidonic acid release and the prostaglandin synthesis. 相似文献