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A Framework for Adapted Nutritional Therapy for Children With Cancer in Low‐ and Middle‐Income Countries: A Report From the SIOP PODC Nutrition Working Group
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Elena J. Ladas PhD RD Brijesh Arora MD DM Scott C. Howard MD Paul C. Rogers MD Terezie T. Mosby EdD RD Ronald D. Barr MB ChB MD 《Pediatric blood & cancer》2016,63(8):1339-1348
The utilization of adapted regimens for the treatment of pediatric malignancies has greatly improved clinical outcomes for children receiving treatment in low‐ and middle‐income countries (LMIC). Nutritional depletion has been associated with poorer outcomes, increased abandonment of therapy, and treatment‐related toxicities. Surveys have found that nutritional intervention is not incorporated routinely into supportive care regimens. Establishing nutritional programs based upon institutional resources may facilitate the incorporation of nutritional therapy into clinical care in a way that is feasible in all settings. We present a framework for establishing and monitoring of nutritional care based on the infrastructure of institutions in LMIC. 相似文献
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David Heseltine Michael Dakkak Ian A. Macdonald PhD Stephen R. Bloom MD John F. Potter DM 《Clinical autonomic research》1991,1(3):219-224
Previous studies have demonstrated that blood pressure falls postprandially in fit elderly subjects, the greatest changes occurring after meals with a high carbohydrate content. To evaluate the influence of the type of carbohydrate on postprandial blood pressure, the effects of equivalent energy content (2.4 MJ) high complex (starch) and high simple (monosaccharide) carbohydrate meals were studied in seven healthy elderly subjects. Blood pressure, heart rate, autonomic function, plasma catecholamines, insulin and neurotensin levels were measured pre- and postprandially. Greater falls in supine and erect systolic blood pressure occurred after the high simple than the high complex carbohydrate meal (p < 0.05). No differences were found in supine or erect diastolic blood pressure, heart rate or in any of the biochemical parameters measured between the meal types. It is concluded that a simple carbohydrate meal results in a greater postprandial fall in blood pressure than an equivalent energy complex carbohydrate meal in the elderly, although the mechanisms for these changes are unknown. 相似文献
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Value of non-invasive continuous blood pressure monitoring in the detection of carotid sinus hypersensitivity 总被引:1,自引:0,他引:1
Christopher J. Mathias DPhil Elaine Armstrong BSc Norman Browse K. R. Chaudhuri Peter Enevoldson DPhil Ralph W. Ross Russell DM 《Clinical autonomic research》1991,1(2):157-159
A patient with recurrent episodes of dizziness and blackouts is described. Detailed cardiac and neurological investigations were normal. Autonomic assessment excluded postural hypotension and confirmed normal sympathetic vasoconstrictor function. Cardiac parasympathetic function in response to deep breathing, hyperventilation and ocular pressure was normal. Left carotid sinus massage only reproducibly lowered blood pressure with minimal change in heart rate. This occurred mainly during head-up tilt. The fall in blood pressure was not affected by the muscarinic blocker atropine, or the peptide release inhibitor, octreotide. A diagnosis of left carotid sinus hypersensitivity of the vasodepressor variety was made. Left carotid sinus denervation was performed. This successfully prevented further episodes of dizziness and blackouts. The ability to measure beat-to-beat blood pressure non-invasively was of particular importance in diagnosis, and in the assessment of management options in this patient. 相似文献
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