全文获取类型
收费全文 | 16153篇 |
免费 | 1297篇 |
国内免费 | 90篇 |
专业分类
耳鼻咽喉 | 145篇 |
儿科学 | 580篇 |
妇产科学 | 416篇 |
基础医学 | 2028篇 |
口腔科学 | 238篇 |
临床医学 | 2040篇 |
内科学 | 3128篇 |
皮肤病学 | 471篇 |
神经病学 | 1522篇 |
特种医学 | 471篇 |
外科学 | 1979篇 |
综合类 | 368篇 |
一般理论 | 10篇 |
预防医学 | 1515篇 |
眼科学 | 269篇 |
药学 | 978篇 |
中国医学 | 6篇 |
肿瘤学 | 1376篇 |
出版年
2021年 | 202篇 |
2020年 | 134篇 |
2019年 | 242篇 |
2018年 | 263篇 |
2017年 | 193篇 |
2016年 | 223篇 |
2015年 | 243篇 |
2014年 | 319篇 |
2013年 | 519篇 |
2012年 | 735篇 |
2011年 | 830篇 |
2010年 | 441篇 |
2009年 | 444篇 |
2008年 | 753篇 |
2007年 | 772篇 |
2006年 | 743篇 |
2005年 | 775篇 |
2004年 | 693篇 |
2003年 | 612篇 |
2002年 | 623篇 |
2001年 | 496篇 |
2000年 | 518篇 |
1999年 | 438篇 |
1998年 | 189篇 |
1997年 | 179篇 |
1996年 | 123篇 |
1995年 | 135篇 |
1994年 | 126篇 |
1992年 | 365篇 |
1991年 | 355篇 |
1990年 | 370篇 |
1989年 | 353篇 |
1988年 | 263篇 |
1987年 | 299篇 |
1986年 | 306篇 |
1985年 | 304篇 |
1984年 | 204篇 |
1983年 | 232篇 |
1982年 | 125篇 |
1979年 | 205篇 |
1978年 | 142篇 |
1977年 | 125篇 |
1976年 | 139篇 |
1975年 | 135篇 |
1974年 | 145篇 |
1973年 | 136篇 |
1972年 | 107篇 |
1971年 | 101篇 |
1970年 | 119篇 |
1969年 | 104篇 |
排序方式: 共有10000条查询结果,搜索用时 421 毫秒
81.
后路脊椎V型截骨术治疗创伤性脊柱后凸畸形 总被引:1,自引:1,他引:0
目的总结应用椎弓根钉-棒系统后路脊椎V型截骨术治疗创伤性脊柱后凸畸形的临床经验、技术要点及效果。方法将创伤性脊柱后凸畸形的病人分为两组,进行对比分析。治疗组:应用椎弓根钉-棒系统后路V型截骨内固定术29例;对照组:应用前路椎体骨折复位内固定融合术26例。结果与对照组相比,治疗组术后畸形复发率显著低于对照组(P〈0.05),断钉、松动等并发症发生率显著低于对照组(P〈0.05),骨折不融合、纠正后凸畸形度数对比无显著性差异(P〉0.05)。结论应用椎弓根钉-棒系统后路V型截骨术治疗的创伤性脊柱后凸畸形可有效防止手术后畸形再发生,矫正后凸畸形彻底、安全、可靠。 相似文献
82.
Andrew M Blamire Sarah Cader Martin Lee Jackie Palace Paul M Matthews 《Magnetic resonance in medicine》2007,58(5):880-885
Axonal damage is a major factor contributing to permanent disability in patients with multiple sclerosis (MS); it has been extensively investigated in the brain using magnetic resonance spectroscopy (MRS). In this study, MRS was used to investigate the degree of neuronal damage in the cervical spinal cord in MS. Spectra were acquired from spinal cord and brain in 11 patients with MS (expanded disability status score [EDSS], range 2.5-7.0) and 11 controls. Brain lesion volume and spinal cord cross-sectional area were measured. Concentration of the neuronal metabolite N-acetyl-aspartate ([NAA]) was reduced in the spinal cord in MS patients relative to controls (reduced by 32%, P < 0.05), indicating significant neuronal damage. Additionally, the spinal cord was significantly atrophied in MS patients (15%, P < 0.001). No significant reduction in brain [NAA] was seen in the MS group. There were no correlations between clinical measures and cord atrophy or brain lesion volume on MRI; however, spinal cord [NAA] correlated with the cerebellar subscore of the neurological assessment (P < 0.005), while brain [NAA] correlated with disease duration (P < 0.05). MRS demonstrated cellular damage within the cord over and above the tissue atrophy seen by MRI. Combining MRI and MRS may therefore give a more complete picture of neurodegeneration in the spinal cord. 相似文献
83.
Histopathological Diagnosis of Partial and Complete Hydatidiform Mole in the First Trimester of Pregnancy 总被引:8,自引:0,他引:8
Neil J. Sebire Rosemary A. Fisher Helene C. Rees 《Pediatric and developmental pathology》2003,6(1):69-77
The diagnosis of molar pregnancy is a continuing diagnostic problem for many practicing histopathologists who are required
to examine specimens of products of conception, particularly since changes in gynecological management in recent years have
resulted in uterine evacuation at earlier gestations. The aim of this review is to provide practical, up-to-date, diagnostically
useful information regarding the histological diagnosis of molar disease in early pregnancy. Pathophysiological issues relevant
to molar pregnancies, such as genetic abnormalities, will be briefly summarized, but nonhistopathological aspects of molar
disease will not be covered in detail in this review. 相似文献
84.
G W Fisher 《Journal of the American Optometric Association》1988,59(8):588-589
85.
86.
Thomas A. Blakely Jr. Francis M. Crinella Todd D. Fisher Lorraine Champaigne Frances W. Beck 《Journal of developmental and physical disabilities》1994,6(1):1-22
Since Samuel Orton's (1937) assertion that dyslexia reflects abnormal brain organization, the relationship of learning disabilities
to brain dysfunction has been the topic of considerable debate. Recently, learning-disabled individuals have been studied
in conjunction with those known to have neurological dysfunction, in a search for common subtypes. In the present study, a
population of 177 children, ages 9-0 to 14-0, were assessed on an augmented version of the Children's Halstead-Reitan Battery.
One hundred twenty-nine Ss were learning-disabled, 37 of whom also had verified brain damage. The remaining 48 children had
neither learning disabilities nor evidence of brain damage. Patterns of neuropsychological performance were determined using
Tryon's clustering methods. The procedure yielded six subject clusters: (A) and (B)—children with low general intellectual
ability; (C) children who are clumsy and lethargic; (D) children with language dysfunction; (E) children with faulty spatial
orientation; and (F) children with no detectable neuropsychological deficits. These clusters were similar to those identified
by investigators who have used other subject-clustering methods. Brain-damaged individuals were more prevalent in some clusters
(e.g., A and B) than in others (e.g., E and F), and substantial numbers of learning disabled subjects were also found in clusters
where brain-damaged individuals tended to cluster, indicating similar neuropsychological profiles. The cluster structure was
validated by comparison with subtypes identified by other investigators, as well as by tests of association between clusters
with exogenous factors (e.g., history of prematurity; seizures). 相似文献
87.
88.
89.
A reversed-phase high-performance liquid chromatographic method using coulometric electrochemical detection in the oxidative mode has been developed for the analysis of 3-(9-chloro-5,6-dihydro-11-H-pyrrolo[2,1-b][3]benzazepine-11-ylidene- N,N-dimethyl-1-propanamine(E)-Z-butenedioate hydrogen maleate (1) in plasma of patients dosed with 2-8 mg/kg/d of the drug. Concentrations as little as 0.1 ng/mL of 1 in plasma can be estimated with a mean coefficient of variation of 7.4 +/- 1.08%. The utility of the procedure was demonstrated by the analysis of 500 patient samples from a rising multiple-dose study. 相似文献
90.
Mary ER O'Brien Janet Hardy Sylvia Tan Jackie Walling Brian Peters Sarah Hatty Eve Wiltshaw 《Cancer chemotherapy and pharmacology》1992,30(3):245-248
Summary A total of 16 patients with recurrent epithelial ovarian cancer were treated with sulofenur (LY 186641), a novel oral sulfonylurea. All subjects had received previous chemotherapy. Anaemia occurred in all 16 patients, 14 of whom required a blood transfusion, and 2/16 patients received methylene blue for breathlessness due to methaemaglobinaemia. Treatment was discontinued in 2/16 cases due to rising liver enzyme values, which reverted to normal on cessation of the drug. There was no nausea or alopecia. Only two minor responses were seen. Plasma drug levels were insufficient to result in antitumour activity as extrapolated from animal data. Further studies that attempt to increase the bioavailability and improve the therapeutic index are warranted. 相似文献