全文获取类型
收费全文 | 231944篇 |
免费 | 52740篇 |
国内免费 | 9028篇 |
专业分类
耳鼻咽喉 | 3181篇 |
儿科学 | 6383篇 |
妇产科学 | 2043篇 |
基础医学 | 32422篇 |
口腔科学 | 7743篇 |
临床医学 | 31777篇 |
内科学 | 43869篇 |
皮肤病学 | 9561篇 |
神经病学 | 20128篇 |
特种医学 | 8762篇 |
外国民族医学 | 45篇 |
外科学 | 27852篇 |
综合类 | 28051篇 |
现状与发展 | 35篇 |
一般理论 | 33篇 |
预防医学 | 17237篇 |
眼科学 | 4794篇 |
药学 | 21926篇 |
121篇 | |
中国医学 | 9601篇 |
肿瘤学 | 18148篇 |
出版年
2024年 | 385篇 |
2023年 | 1789篇 |
2022年 | 4559篇 |
2021年 | 7509篇 |
2020年 | 9525篇 |
2019年 | 14410篇 |
2018年 | 13943篇 |
2017年 | 15203篇 |
2016年 | 15870篇 |
2015年 | 17981篇 |
2014年 | 19602篇 |
2013年 | 20516篇 |
2012年 | 16560篇 |
2011年 | 17319篇 |
2010年 | 18420篇 |
2009年 | 13436篇 |
2008年 | 12020篇 |
2007年 | 10917篇 |
2006年 | 10243篇 |
2005年 | 9079篇 |
2004年 | 7350篇 |
2003年 | 7487篇 |
2002年 | 6205篇 |
2001年 | 5142篇 |
2000年 | 4243篇 |
1999年 | 2974篇 |
1998年 | 1512篇 |
1997年 | 1542篇 |
1996年 | 1110篇 |
1995年 | 969篇 |
1994年 | 841篇 |
1993年 | 528篇 |
1992年 | 720篇 |
1991年 | 573篇 |
1990年 | 528篇 |
1989年 | 457篇 |
1988年 | 395篇 |
1987年 | 351篇 |
1986年 | 279篇 |
1985年 | 239篇 |
1984年 | 150篇 |
1983年 | 119篇 |
1982年 | 65篇 |
1981年 | 67篇 |
1980年 | 42篇 |
1979年 | 74篇 |
1978年 | 56篇 |
1976年 | 55篇 |
1974年 | 38篇 |
1973年 | 46篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
31.
32.
Henry Ho‐Lung Chan 《Clinical & experimental optometry》2005,88(6):410-414
The first‐order kernel analysis in multifocal electroretinogram (mfERG) using low contrast stimulation is suggested as a way to detect the inner retinal responses in animal studies. In this case report, this protocol is applied to human patients with glaucoma to demonstrate the possibility of using mfERG as a tool to detect glaucomatous damage. Two patients with glaucoma were recruited and had mfERG measurements with the 103‐scaled hexagonal stimulus pattern at low (50 per cent) contrast. Their responses were analysed and compared with those from normal subjects with the mfERG measured under the same condition. In the normal subjects, there were obvious oscillatory components on the ascending and descending limbs of the first‐order kernel response to 50 per cent contrast. In the glaucomatous patients, the oscillatory component on the descending limb was obviously diminished. In addition, this component was significantly diminished in the quadrant with a glaucomatous visual field defect. This suggests that the low‐contrast stimulation condition in mERG measurement may provide a good way to detect glaucomatous damage and this may help in clinical diagnosis of glaucoma. 相似文献
33.
目的 合理应用影像学检查,探讨腰腿痛的病因诊断,为临床治疗提供依据.方法 对38例腰腿痛患者进行随访,观察普通照片后经CT、MRI及B超等复查的最后诊断,对比进行分析.结果 单纯普通照片对椎间盘脱出、椎管狭窄、骶部硬膜外囊肿、股骨头无菌坏死、梨状肌损伤等疾病缺乏直接征象,不能作为诊断依据.结论 应用CT、MRI现代影像技术,同时借助B超、肌电图等相关检查,是确诊腰腿痛病因的有效方法. 相似文献
34.
35.
E. Wieczerzak E. Jankowska S. Rodziewicz‐Motowido A. Giedo J. giewka Z. Grzonka M. Abrahamson A. Grubb D. Brmme 《Chemical biology & drug design》2005,66(Z1):1-11
Abstract: We have designed and synthesized a new series of azapeptides which act as potential inhibitors of cathepsin B and/or cathepsin K. Their structures are based upon the inhibitory sites of natural cysteine protease inhibitors, cystatins. For the synthesized azapeptides, the equilibrium constants for dissociation of inhibitor–enzyme complex, Ki, were determined. Comparison of these values indicated that all of the azainhibitors act much stronger toward cathepsin B. Z‐Arg‐Leu‐His‐Agly‐Ile‐Val‐OMe ( 7 ) proved to be approximately 500 times more potent for cathepsin B than for cathepsin K. To be able to explain the obtained experimental values we used the molecular dynamics procedures to analyze the interactions between cathepsin B and compound 7 . We also determined the structure of the most potent and selective cathepsin B azainhibitor by means of NMR studies and theoretical calculations. In this report, we describe SAR studies of azapeptide inhibitors indicating the influence of the conformational flexibility of the examined compounds on inhibition of cathepsins B and K. 相似文献
36.
37.
38.
1 The internal anal sphincter (IAS) has a spontaneous tone and is the main contributor to the maintenance of faecal continence. The spontaneous resting tone exhibited by the sphincter can be modified by neurotransmitters from the autonomic and enteric nervous systems. 2 In this review, the influence of the sympathetic and parasympathetic nervous systems on IAS tone are discussed and the putative roles of nitric oxide, carbon monoxide, vasoactive intestinal peptide and adenosine triphosphate in non‐adrenergic non‐cholinergic transmission are considered. 3 Faecal incontinence is a common condition that places a heavy financial burden on the health service and severely affects patients’ quality of life. Resting anal pressure is reduced in patients with faecal incontinence and agents that increase sphincter tone tend to relieve symptoms. The results of clinical studies of the use of phenylephrine to treat faecal incontinence are reviewed. 4 It is concluded that the IAS is a potential target for drug development for the treatment of faecal incontinence. 相似文献
39.
试析陆懋修从阳明论治温病之特色 总被引:1,自引:0,他引:1
陆懋修(1818-1886),又名免研,字九芝,号江左下工,又号林屋山人,江苏元和(今江苏吴县)人,为清代后期著名的医学家。陆氏出身于官宦之家,儒医兼通,陆氏秉承家学,对先人的医学成就颇为敬重。他曾三十余年坚持潜心研究《内经》、《伤寒》等医学经典著作,终于贯通医理而成为一代名医。陆氏一生博览群书之余,著述不断, 相似文献
40.