全文获取类型
收费全文 | 3295篇 |
免费 | 202篇 |
国内免费 | 36篇 |
专业分类
耳鼻咽喉 | 84篇 |
儿科学 | 42篇 |
妇产科学 | 51篇 |
基础医学 | 380篇 |
口腔科学 | 31篇 |
临床医学 | 133篇 |
内科学 | 1048篇 |
皮肤病学 | 42篇 |
神经病学 | 303篇 |
特种医学 | 75篇 |
外科学 | 763篇 |
综合类 | 8篇 |
预防医学 | 66篇 |
眼科学 | 39篇 |
药学 | 150篇 |
中国医学 | 3篇 |
肿瘤学 | 315篇 |
出版年
2024年 | 3篇 |
2023年 | 37篇 |
2022年 | 64篇 |
2021年 | 94篇 |
2020年 | 64篇 |
2019年 | 99篇 |
2018年 | 110篇 |
2017年 | 84篇 |
2016年 | 107篇 |
2015年 | 87篇 |
2014年 | 152篇 |
2013年 | 154篇 |
2012年 | 269篇 |
2011年 | 248篇 |
2010年 | 126篇 |
2009年 | 109篇 |
2008年 | 205篇 |
2007年 | 219篇 |
2006年 | 209篇 |
2005年 | 209篇 |
2004年 | 192篇 |
2003年 | 186篇 |
2002年 | 150篇 |
2001年 | 23篇 |
2000年 | 26篇 |
1999年 | 44篇 |
1998年 | 44篇 |
1997年 | 35篇 |
1996年 | 22篇 |
1995年 | 17篇 |
1994年 | 26篇 |
1993年 | 14篇 |
1992年 | 15篇 |
1991年 | 16篇 |
1990年 | 6篇 |
1989年 | 5篇 |
1988年 | 9篇 |
1987年 | 7篇 |
1986年 | 5篇 |
1985年 | 5篇 |
1984年 | 5篇 |
1983年 | 3篇 |
1982年 | 5篇 |
1981年 | 6篇 |
1979年 | 6篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1967年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有3533条查询结果,搜索用时 15 毫秒
41.
The results of surgical treatment for a ruptured type B aortic dissection remain far from satisfactory. It is believed that
additional perfusion from the right axillary artery might be more beneficial than perfusion from only the femoral artery during
surgery for a ruptured thoracic aneurysm. The right axillary perfusion is more likely to perfuse the vital organs proximal
to the ruptured area, and thus avoid retrograde emboli. In addition, if the open proximal method is performed, then the right
axillary perfusion is able to facilitate the evacuation of air from the aortic lumen. We present herein the case of a patient
in whom a ruptured type B acute aortic dissection was successfully treated by applying right axillary perfusion through a
left thoracotomy. 相似文献
42.
Finger bougie method compared with pyloroplasty in the gastric replacement of the esophagus 总被引:2,自引:0,他引:2
Yamashita Y Hirai T Mukaida H Yoshimoto A Kuwahara M Inoue H Toge T 《Surgery today》1999,29(2):107-110
To elucidate the necessity of pyloroplasty for the gastric tube through the posterior mediastinum in esophageal surgery, gastric
emptying and duodenogastric reflux (DGR) were evaluated in 16 cases undergoing an anterior pylorectomy (group P) and in 16
cases treated by the finger bougie method (group F). First, the obstruction and reflux symptoms were examined based on a patient
questionnaire using a brief scoring system. The median value of the symptom score showed the patients in P to have more symptoms
than those in F; however, the difference was not significant (8.0 vs 6.0). Secondly, the swallowed Tc O4
− (85 MBq) was counted using a gamma camera at three sites on the sternal bone in the upright position based on a gastric transit
scintigram. Both the descending time of the RI peak and the clearance rates were similar between the two groups. Thirdly,
intragastric 24-h pH monitoring was carried out. Antimony pH sensors were anchored 5 and 15 cm below the esophagogastrostomy.
We could not find any difference between the two groups in both the % time pH>4 and %time pH>7. These findings thus revealed
no big difference between groups P and F. The finger bougie method to drain the vagotomized posterior mediastinal stomach
was found to achieve results similar to conventional pyloroplasty, while it was also simpler and safer. 相似文献
43.
Inagaki M Yabuki H Hashimoto M Maguchi M Kino S Sawa M Ojima H Tokusashi Y Miyokawa N Kusano M Kasai S 《Surgery today》1999,29(12):1260-1263
We describe herein the case of a 51-year-old woman in whom metastatic tumor seeding of the percutaneous transhepatic biliary
drainage tract occurred following a pancreatoduodenectomy for carcinoma of the distal common bile, duct. An abdominal computed
tomography scan done 6 months after the initial operation detected a hepatic lesion located at the site of the previous percutaneous
transhepatic biliary drainage tract. Implantation of bile duct carcinoma in the drainage tract was diagnosed, and the recurrent
tumor was successfully resected by performing a subsegmentectomy of segment 3 and removal of the adjacent abdominal wall.
At present, 5 years and 4 months after the second resection, the patient is in good health without any signs of recurrence.
This case report demonstrates that an aggressive surgical approach should be performed for tumor seeding of a transhepatic
biliary catheter tract. 相似文献
44.
Tetsuo Hadama Yoshiaki Mori Osamu Shigemitsu Tatsunori Kimura Shinji Miyamoto Hidenori Sako Tooru Soeda Toshihide Yoshimatsu Yuzo Uchida 《Surgery today》1996,26(1):60-63
We report herein the rare case of a 79-year-old man who suffered permanent paraplegia after undergoing an otherwise successful total arch replacement for a ruptured aortic arch aneurysm. During cardiopulmonary bypass, perfusion to the distal aorta was maintained from the femoral artery, and postoperative aortography showed intact tributaries from the aorta including the intercostal arteries. Postoperative paraplegia is an extremely rare complication of operations on the aortic arch; however, we speculate that the paraplegia in this patient could be attributed either to a steal phenomenon involving the radicular artery, or to the anatomical particularity of the spinal cord artery described by Cole and Gutelius as the segmental system. 相似文献
45.
Penetration of etoposide into human malignant brain tumors after intravenous and oral administration
Katsuzo Kiya Tohru Uozumi Hidenori Ogasawara Kazuhiko Sugiyama Takuhiro Hotta Takashi Mikami Kaoru Kurisu 《Cancer chemotherapy and pharmacology》1992,29(5):339-342
Summary Penetration of etoposide into the cerebrospinal fluid, brain tumor, and brain tissue after intravenous administration was investigated in patients presenting with malignant brain tumors. A relatively low dose (55–65 mg/m2) was used to compare intravenous with oral administration. High-performance liquid chromatography with fluorescence detection was used to evaluate drug levels. Plasma and cerebrospinal fluid levels of etoposide after oral administration (50–150 mg/day) were also studied so as to determine the adequate oral dose for the treatment of malignant brain tumors. The peak plasma concentration after intravenous administration ranged from 7.01 to 10.47 g/ml, varying in proportion to the injected dose, whereas that after oral administration was lower, namely, 1.44–4.99 g/ml, and was unstable when the oral dose was 150 mg daily. The peak cerebrospinal fluid level following either intravenous or oral administration was much lower than the plasma concentration and was influenced by the peak plasma level and the sampling site. The etoposide concentration in cerebrospinal fluid taken from the subarachnoid space and ventricle of patients displaying no tumor invasion and of those presenting with meningeal carcinomatosis and in cerebrospinal fluid taken from the dead space after tumor resection was 0.7%±0.5%, 3.4%±1.0%, and 7.2% ± 8.5%, respectively, of the plasma concentration. Serial oral administration did not result in the accumulation of etoposide in cerebrospinal fluid. The tumor concentration (1.04–4.80 g/g) was 14.0%±2.9% of the plasma level after intravenous administration, was related to the injected dose, and was approximately twice the concentration detected in the brain tissue. Therefore, a relatively low dose of etoposide injected intravenously penetrates the brain tumor at an efficacious concentration. Our results indicate than an oral dose of 100 mg etoposide be given for malignant brain tumors, as limited penetration of the drug into the intracranial region was observed. 相似文献
46.
47.
Toshihisa Murofushi Atsushi Ochiai Hidenori Ozeki Shinichi Iwasaki 《International journal of audiology》2013,52(2):66-68
To clarify the laterality of acoustically evoked vestibulocollic reflexes with a short latency (vestibular evoked myogenic potentials, VEMPs), responses on the bilateral sternocleidomastoid muscles (SCMs) to unilateral acoustic stimulation were studied. Twenty-one healthy volunteers were enrolled. Surface electrodes were placed on the upper half of each SCM (active) and on the lateral end of the upper sternum (reference). Clicks and 500-Hz tone-bursts (95 dB nHL) were used. All subjects showed positive-negative biphasic responses on the ipsilateral SCM by clicks and tone-bursts. Click-stimulation of 41 of the 42 ears did not evoke any response on the contralateral SCM. However, in one ear, positive-negative biphasic responses were evoked on the contralateral SCM. Recordings on the contralateral SCM by tonebursts showed no response in 32 ears, small positive-nega-tive biphasic responses in four ears, and small negative-positive biphasic responses in six ears. These findings show that VEMPs are ipsilateral-dominant, basically consistent with the hypothesis that they are of saccular origin. 相似文献
48.
49.
Real‐world efficacy and safety of daclatasvir and asunaprevir therapy for hepatitis C virus‐infected cirrhosis patients 下载免费PDF全文
Kei Morio Michio Imamura Yoshiiku Kawakami Reona Morio Tomoki Kobayashi Satoe Yokoyama Yuko Nagaoki Tomokazu Kawaoka Masataka Tsuge Akira Hiramatsu Grace Naswa Makokha C Nelson Hayes Hiroshi Aikata Daiki Miki Hidenori Ochi Yoji Honda Nami Mori Shintaro Takaki Keiji Tsuji Kazuaki Chayama 《Journal of gastroenterology and hepatology》2017,32(3):645-650