全文获取类型
收费全文 | 522篇 |
免费 | 102篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 17篇 |
妇产科学 | 6篇 |
基础医学 | 29篇 |
口腔科学 | 9篇 |
临床医学 | 75篇 |
内科学 | 137篇 |
神经病学 | 54篇 |
特种医学 | 193篇 |
外科学 | 49篇 |
综合类 | 10篇 |
预防医学 | 14篇 |
眼科学 | 2篇 |
药学 | 15篇 |
肿瘤学 | 17篇 |
出版年
2023年 | 11篇 |
2021年 | 6篇 |
2020年 | 5篇 |
2019年 | 1篇 |
2018年 | 26篇 |
2017年 | 10篇 |
2016年 | 17篇 |
2015年 | 20篇 |
2014年 | 39篇 |
2013年 | 46篇 |
2012年 | 4篇 |
2011年 | 14篇 |
2010年 | 32篇 |
2009年 | 43篇 |
2008年 | 23篇 |
2007年 | 11篇 |
2006年 | 12篇 |
2005年 | 12篇 |
2004年 | 13篇 |
2003年 | 6篇 |
2002年 | 7篇 |
2001年 | 11篇 |
2000年 | 8篇 |
1999年 | 8篇 |
1998年 | 21篇 |
1997年 | 23篇 |
1996年 | 16篇 |
1995年 | 13篇 |
1994年 | 11篇 |
1993年 | 16篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 7篇 |
1989年 | 21篇 |
1988年 | 16篇 |
1987年 | 13篇 |
1986年 | 8篇 |
1985年 | 13篇 |
1984年 | 4篇 |
1983年 | 4篇 |
1982年 | 9篇 |
1981年 | 6篇 |
1980年 | 9篇 |
1979年 | 4篇 |
1978年 | 3篇 |
1977年 | 6篇 |
1976年 | 7篇 |
1975年 | 4篇 |
1971年 | 1篇 |
1961年 | 1篇 |
排序方式: 共有629条查询结果,搜索用时 15 毫秒
71.
The management of stage I--II Hodgkin's disease with irradiation alone or combined modality therapy: the Stanford experience 总被引:1,自引:0,他引:1
At Stanford University, between 1968 and 1978, 230 patients with pathologic stage I--II Hodgkin's disease were treated on prospective clinical trials with either irradiation alone or irradiation followed by 6 cycles of adjuvant combination chemotherapy. The actuarial survival at 10 yr was 84% for patients in either treatment group. Freedom from relapse at 10 yr was 77% among patients treated with irradiation alone and 84% after treatment with combined modality therapy [p(Gehan) = 0.09]. Freedom from second relapse at 10 yr was 89% and 94%, respectively [p(Gehan) = 0.56]. Several prognostic factors were evaluated in order to identify patients at high risk for relapse or with poor ultimate survival after initial treatment with irradiation alone. Systemic symptoms, histologic subtype, age, and limited extranodal involvement (E-lesions) did not affect the prognosis of patients and failed to identify patients whose survival could be improved by the routine use of combined modality therapy. Patients with large mediastinal masses (mediastinal mass ratio greater than or equal to 1/3) had a significantly poorer freedom from relapse when treated with irradiation alone than when treated initially with combined modality therapy [45% versus 81% at 10 yr, p(Gehan) = 0.03). The 10-yr survival of these patients, however, was not significantly different (84% versus 74%). The implications of these observations on the management of patient with early stage Hodgkin's disease are discussed. 相似文献
72.
73.
Masato Hashimoto MD PhD Kenji Ohtsuka MD PhD Hidenari Akiba MD Kuniaki Harada RT 《American journal of ophthalmology》1998,125(6):881-882
Purpose: To describe the thin-slice magnetic resonance imaging features of vascular compressive oculomotor nerve paresis.Methods: We performed thin-slice (2 mm thick) magnetic resonance imaging of the brainstem in a 74-year-old woman with right partial oculomotor nerve paresis using spoiled gradient recalled acquisition in the steady state.Results: Thin-slice magnetic resonance images disclosed that the right oculomotor nerve was compressed and dislocated superiorly and laterally by the tortuous basilar artery. No other abnormalities were observed.Conclusion: This is the first case report of vascular compressive oculomotor nerve paresis disclosed by thin-slice magnetic resonance imaging. 相似文献
74.
We have found that the addition of 10 mM inorganic phosphate to DHA in CPD-adenine maintains ATP levels at normal or higher than normal values for six weeks of storage. 2,3-DPG values are slightly lowered by the extra phosphate, but are still maintained at approximately half normal for four weeks by the DHA. The addition of a higher phosphate concentration, 20 mM, to DHA produced lower levels of ATP and 2,3-DPG than those observed with 10 mM phosphate, although both levels were better than in the CPD-adenine control. pH values in this experiment were lowest in the three preservatives containing DHA, probably indicating increased lactate production due to metabolism of this triose sugar, in addition to dextrose present in CPD. 相似文献
75.
76.
77.
Ejection fraction image: A noninvasive index of regional left ventricular wall motion 总被引:10,自引:0,他引:10
78.
79.
80.
Priya M Miranda Viswanathan Mohan Sekhar Ganthimathy Ranjit M Anjana S Gunasekaran Venkatachalam Thiagarajan Thomas A Churchill Tatsuya Kin AM James Shapiro Jonathan RT Lakey 《Islets》2013,5(5):188-195
The aim of this study was to assess recovery, cell death, and cell composition of post-thaw cultured human islets. Cryopreserved islets were provided by the Clinical Islet Transplant Program, Edmonton, Canada. Islets were processed using media prepared in accordance with Pre-Edmonton and Edmonton protocols. Cryopreserved islets were rapidly thawed and cultured for 24 h, 3 d, 5 d, and 7 d, following which they were processed for histology. Islet quantification, integrity, morphology and tissue turnover were studied via hematoxylin and eosin stained sections. Ultrastructure was studied by electron microscopy and endocrine cell composition by immunohistochemistry. Using the Pre-Edmonton protocol, islet recovery was 50.1% and islet survival was 50% at 24 h while for the Edmonton protocol, the islet recovery was 69.4% (p < 0.001) and islet survival, 50% at ≈2.5 d. With an increasing culture duration although the physical integrity was retained there was an increasing loss of cohesivity both at light microscopic and at ultrastructure level regardless of the protocols used. Percentage islet survival and tissue turnover correlated negatively with culture duration in both protocols. The Edmonton protocol appears to preserve the islets better. However, culture duration adversely affects islet survival and quality, indicating the need for more optimal cryopreservation and culture techniques. 相似文献