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11.
A Csendes A Sepúlveda P Burdiles I Braghetto J Bastias H Schütte J C Díaz J Yarmuch F Maluenda 《Archives of surgery (Chicago, Ill. : 1960)》1988,123(6):697-699
Resting common bile duct pressure was measured in three groups of patients: group 1, 53 patients with gallstones but without common duct stones; group 2, 35 patients with common bile duct stones unaccompanied by cholangitis; and group 3, 36 patients with common duct stones and acute suppurative cholangitis. A significantly higher pressure in the common bile duct was documented in patients with cholangitis when compared with the other two groups. Twenty-four patients with cholangitis had common duct pressure values above 20 cm H2O, the maximal values of normal. Additionally, patients with cholangitis with pressure values over 30 cm H2O (nine patients) showed absence of green bile in the extrahepatic biliary tract, suggesting cessation of bile excretion into biliary duct. In all these cases, an impacted stone at the distal end of the common bile duct was documented. 相似文献
12.
R. Siebert C. Willers W. Bardenheuer S. Michaelis A. Lux A. Schramm A. Gockel H. Luboldt B. Opalka J. Schütte 《Journal of cancer research and clinical oncology》1995,121(Z1):A36
contributed equally to this work 相似文献
13.
Timo Laatikainen Henri Kurunmäki Aarne Koskimies 《Journal of assisted reproduction and genetics》1988,5(1):14-17
Of 70 cycles stimulated with clomiphene and human menopausal gonadotropin (hMG) for an in vitro fertilization-embryo transfer (IVF-ET) program, a short luteal phase of 11 days or less was found in 18. In this group the mean estradiol and progesterone levels were elevated in the early luteal phase. Despite the elevated initial values, progesterone levels fell rapidly at the mid luteal phase as a sign of premature luteolysis. The mean total amount of gonadotropin administered and the mean number of follicles punctured and of oocytes recovered did not show any significant difference between the groups of normal and short luteal phases. The present findings support the theory that hyperestrogenism in the early luteal phase may initiate the premature luteolysis observed in clomiphene-menopausal gonadotropin-stimulated cycles. 相似文献
14.
M Jütte S Klein D Katenkamp W Vogel W G?tz R Woytinas 《Klinische Monatsbl?tter für Augenheilkunde》1992,200(6):674-677
The results with two new enucleation prothesis made of Bioverit are presented. After unilateral enucleation 14 rabbits received bioreactive, 14 rabbits biocompatible and 9 rabbits nylon prostheses. Implantation periods: 1-13 months. The tissue surrounding of the prostheses was studied histologically, the ceramic electron microscopically. Of 28 ceramic prostheses, 26 were adapted very well. Bioverit ist excellently suited as orbital prosthetic material, even half-open implants are possible. 相似文献
15.
Gangliosides of cultured astroglia 总被引:3,自引:0,他引:3
Michele Sbaschnig-Agler Henri Dreyfus William T. Norton Monique Sensenbrenner Muhammad Farooq Mary C. Byrne Robert W. Ledeen 《Brain research》1988,461(1):98-106
Cultured astrocytes prepared from newborn rat brain and 13-day-old chick embryonic brain were analyzed qualitatively and quantitatively for ganglioside content. All preparations contained approximately the same total level: 2.4-3.4 micrograms N-acetylneuraminic acid (NeuAc)/mg protein. In contrast, the value for primary cultures of neurons from chick embryonic brain was 5.9. The non-hexosamine-containing species, GM3 and GD3, comprised 75-85% of the total in astroglial cultures, the remainder consisting mainly of structural types other than the gangliotetraose series; choleragenoid assay revealed the latter to be virtually absent or to comprise at most a few percent. Deficiency of gangliotetraose synthesizing ability was indicated by the very low level of UDP-GalNac:GM3 N-acetylgalactosaminyltransferase detected in the cells. Treatment of cultured astrocytes with astroglial growth factor 2 or dibutyryl cyclic AMP caused little if any change in quantity or pattern of gangliosides. The large majority of cells stained in a manner characteristic of astrocytes: positive for glial fibrillary acidic protein, negative for galactosyl ceramides. Staining with cholera toxin and anti-GM1 antibody was essentially negative, as was that with tetanus toxin, A2B5 monoclonal antibody, and antibody to GD3. All evidence thus points to cultured astrocytes of rat and chick brain containing appreciable gangliosides, most of which are GM3 and GD3 with the majority of the remainder comprising structures other than the gangliotetraose type. 相似文献
16.
Walking exercise in patients with intermittent claudication. Experience in routine clinical practice. 下载免费PDF全文
Marie-Louise Bartelink Henri E J H Stoffers Cornelis J Biesheuvel Arno W Hoes 《The British journal of general practice》2004,54(500):196-200
BACKGROUND: In patients with intermittent claudication, exercise in the form of walking is effective in reducing pain and maximising achievable walking distance. However, data are lacking on the implementation of walking exercise in these patients. AIMS: To explore the current behaviour and views of patients with intermittent claudication towards taking walking exercise. DESIGN OF STUDY: Postal questionnaire and focus group meetings. SETTING: Two academic general practice networks (Utrecht and Maastricht Universities) in The Netherlands. METHOD: Three hundred and seventy-five patients with intermittent claudication, selected from the files of general practitioners participating in two academic general practice networks, were sent a postal questionnaire; 216 (58%) were returned. Nine of these responders also attended a focus group meeting. RESULTS: Seventy per cent (151/216) of the patients reported having received advice about walking exercise. If specified, the advice given most often recommended walking in the local neighbourhood (56%, 84/151). Fifty-two per cent (113/216) of all patients actually performed walking exercise and only 32%of them received any kind of supervision. Among the barriers for taking walking exercise, 'comorbidity', 'lack of (specific) advice' and 'lack of supervision' were often mentioned. Among the stimuli to start and continue walking, 'following the doctor's advice', 'relief of complaints' and 'a better general condition' were often mentioned by patients. CONCLUSIONS: Walking exercise was not carried out by almost half of patients with intermittent claudication in this study. Lack of specific advice and supervision were found to be important barriers to taking walking exercise. 相似文献
17.
Salom El Hage Michle Ane Jean-Luc Stigliani Maynadier Marjorie Henri Vial Genevive Baziard-Mouysset Marc Payard 《European journal of medicinal chemistry》2009,44(11):4778-4782
In this paper we describe the design and synthesis of 18 derivatives of the antimicrobial atovaquone which were substituted at the 3-hydroxy group by ester and ether functions. The compounds were evaluated in vitro for their activity against the growth of Plasmodium falciparum, the malaria causing parasite. All the compounds showed potent activity, with IC50 values in the range of 1.25–50 nM, comparable to those of atovaquone and much higher than chloroquine or quinine. 相似文献
18.
19.
A. S. Pinto M. de Lana B. Bastrenta C. Barnabé V. Quesney S. Noël M. Tibayrenc 《Parasitology research》1998,84(5):348-353
A total of 15 mixtures involving 9 different stocks attributed to the 19/20, 32 and 39 major clonal genotypes of Trypanosoma cruzi were used to infect third-instar nymphs of Triatoma infestans via an artificial feeding device. Three biological parameters were considered: (1) the percentage of infected insects (%II),
(2) the number of flagellates per insect (NFI), and (3) the percentage of trypomastigotes per insect (%DIF). Genetic characterization
by both multilocus enzyme electrophoresis (MLEE) and random amplification of polymorphic DNA (RAPD) indicated that in almost
all cases (87%), mixtures remained present after completion of the whole cycle in the insect vector. Two lines of comparison
were performed: (1) pure clonal genotypes versus corresponding mixed clonal genotypes and (2) the␣actual behavior of mixed
clonal genotypes versus the expected behavior of the theoretical mixture (i.e. the␣arithmetic mean of the results observed
for each of the two clonal genotypes taken separately). Statistical analyses of the variables were made difficult because
of the presence of large standard deviations. Nevertheless, in several cases, mixtures differed significantly from pure clonal
genotypes, and in one case the actual mixture differed significantly from the theoretical mixture. In some cases, interaction
(either potentialization or reciprocal inhibition) could be suspected.
Received: 10 March 1997 / Accepted: 21 September 1997 相似文献