全文获取类型
收费全文 | 5682篇 |
免费 | 678篇 |
国内免费 | 55篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 265篇 |
妇产科学 | 267篇 |
基础医学 | 874篇 |
口腔科学 | 135篇 |
临床医学 | 588篇 |
内科学 | 1000篇 |
皮肤病学 | 167篇 |
神经病学 | 527篇 |
特种医学 | 262篇 |
外科学 | 637篇 |
综合类 | 152篇 |
一般理论 | 5篇 |
预防医学 | 647篇 |
眼科学 | 151篇 |
药学 | 355篇 |
1篇 | |
中国医学 | 24篇 |
肿瘤学 | 344篇 |
出版年
2021年 | 68篇 |
2020年 | 37篇 |
2019年 | 65篇 |
2018年 | 92篇 |
2017年 | 87篇 |
2016年 | 94篇 |
2015年 | 85篇 |
2014年 | 121篇 |
2013年 | 162篇 |
2012年 | 205篇 |
2011年 | 206篇 |
2010年 | 161篇 |
2009年 | 173篇 |
2008年 | 212篇 |
2007年 | 268篇 |
2006年 | 246篇 |
2005年 | 199篇 |
2004年 | 192篇 |
2003年 | 192篇 |
2002年 | 208篇 |
2001年 | 199篇 |
2000年 | 197篇 |
1999年 | 192篇 |
1998年 | 139篇 |
1997年 | 128篇 |
1996年 | 111篇 |
1995年 | 91篇 |
1994年 | 82篇 |
1993年 | 98篇 |
1992年 | 140篇 |
1991年 | 121篇 |
1990年 | 132篇 |
1989年 | 140篇 |
1988年 | 116篇 |
1987年 | 135篇 |
1986年 | 114篇 |
1985年 | 117篇 |
1984年 | 98篇 |
1983年 | 88篇 |
1982年 | 64篇 |
1981年 | 44篇 |
1980年 | 59篇 |
1979年 | 68篇 |
1978年 | 57篇 |
1977年 | 57篇 |
1976年 | 49篇 |
1975年 | 46篇 |
1974年 | 53篇 |
1973年 | 53篇 |
1972年 | 46篇 |
排序方式: 共有6415条查询结果,搜索用时 46 毫秒
31.
32.
E Dobremez Y Lefevre L Harper L Rebouissoux F Lavrand J M Bondonny P Vergnes 《Zeitschrift für Kinderchirurgie》2006,16(3):166-170
AIM: Conservative management of splenic rupture in haemodynamically stable children is now generally accepted. However, during follow-up, many complications can occur. The aim of this study was to describe the complications we observed and to propose a standardised follow-up adapted to them. METHODS: Between March 1992 and December 2002 we managed 65 children (aged between 3 and 15 years old) with accidental splenic rupture. Follow-up and treatment consisted of a 10-day bed rest with sonogram and Doppler controls on the 5th and 10th day and subsequently every month until complete healing. Complications included secondary haemorrhage in 3 cases, cystic evolution in 5 cases, and pseudo-aneurysm in 2 cases. All were treated by renewed bed rest. Three of the cysts resolved spontaneously, the other two underwent cystic resection and epiploplasty by laparotomy (n = 1) or laparoscopy (n = 1) and both pseudo-aneurysms were selectively embolised. There were no splenectomies. CONCLUSIONS: Complications essentially occurred in older children and were not related to gender, type of fracture, or extent of bleeding. Cystic evolution of the sub-capsular haematomas can appear up to 1 month after trauma. Peripheral pseudo-aneurysms which could be responsible for secondary haemorrhages were selectively embolised. We favour the use of the Doppler sonogram for follow-up until total recovery of these patients, even in low-grade traumas. Considering the number of complications encountered we do not believe the American evidence-based guidelines are suitable for our population. 相似文献
33.
The synthesis and localization of alternatively spliced fibronectin EIIIB in resting and thrombin-treated megakaryocytes 总被引:1,自引:1,他引:0
There are several species of alternatively spliced fibronectin (FN). One of these, FN EIIIB, is primarily present in embryonic and in proliferating and migrating cells and is believed to be important for cell maturation. We have studied the synthesis, localization, and secretion of this FN isoform in isolated guinea pig megakaryocytes, nonmegakaryocytic bone marrow cells, and platelets. There was 7.5 times more general FN in megakaryocytes than in nonmegakaryocytic cells based on the analysis of equivalent amounts of protein. FN EIIIB was detected by Western blotting in megakaryocytes but not in nonmegakaryocytic cells present in bone marrow. Neither megakaryocytes nor platelets secreted FN EIIIB, while megakaryocytes secreted 25.3% +/- 4.6% general FN and platelets secreted about 61% general FN in response to thrombin. Analysis of immunostained cells by confocal microscopy revealed that FN EIIIB had been redistributed to the surface of megakaryocytes in response to thrombin. Synthesis was studied by metabolic labeling, and megakaryocytes were shown to synthesize FN and FN EIIIB. Thus, megakaryocytes and platelets are among a small number of adult cells and tissues that synthesize and contain FN EIIIB. The expression of FN EIIIB on the megakaryocyte surface may influence migration and maturation. 相似文献
34.
Intestinal schistosomiasis japonica: CT-pathologic correlation 总被引:1,自引:0,他引:1
Lee RC; Chiang JH; Chou YH; Rubesin SE; Wu HP; Jeng WC; Hsu CC; Tiu CM; Chang T 《Radiology》1994,193(2):539
35.
36.
D. J. Kerr G. J. Rustin S. B. Kaye P. Selby N. M. Bleehen P. Harper M. H. Brampton 《British journal of cancer》1995,72(5):1267-1269
Rhizoxin is a tubulin-binding anti-neoplastic agent which is active in a range of murine tumour models. The recommended schedule, of intravenous (i.v.) bolus administration at a dose of 2 mg m-2 every 3 weeks, has been assessed in three phase II trials of ovarian, renal and colorectal cancer. In general terms the drug was fairly well tolerated, but the response rate was disappointing: 0/18, colorectal cancer; 0/18, renal cancer; 1 partial response (PR)/17, ovarian cancer. 相似文献
37.
M Harper 《Occupational and environmental medicine》1988,45(9):602-605
A historical survey into the occupational hazards of mining and refining arsenic is presented together with the measures adopted for their control. The industry is placed in the social perspective of its time and it is suggested that this experience could be of value to those who may encounter similar problems where arsenic is extracted elsewhere in the world. 相似文献
38.
Parapelvic renal cysts are uncommon in children. We report a case occurring in a 2-year-old girl, diagnosed during follow-up for blood hypertension. The cyst measured 8 cm in length. There was associated hydronephrosis, due to obstruction of the renal pelvis. Surgical resection was performed. Normotension returned within 3 months, and the obstruction disappeared. A renovascular mechanism can be evoked to explain hypertension. 相似文献
39.
In Wales, predictive testing for Huntington's disease (HD) has not been offered proactively to families and uptake of testing is low in comparison to other centres. Little is known of those not requesting testing, particularly those not in direct contact with the genetics service. This study examined differences between a cohort of 22 test applicants and a random group of 32 'non-requesters', drawn from the South Wales HD register. Respondents were interviewed by means of a semi-structured schedule in their own homes. The study groups differed significantly on a number of variables including: knowledge of the availability of testing; perceived attitudes of family members and significant others to testing; length of knowledge and perceived stressfulness of being at risk; and perceived ability to cope with an unfavourable result. Overall, knowledge of testing procedures was poor and at-risk individuals' understanding of genetic terminology was at odds with scientific distinctions. Discussion focuses on the organisational and psychological factors associated with lack of knowledge of the availability of testing and the interpretation of reported coping capacities. 相似文献
40.
Lesley Barclay RN CM BA MEd Louise Everitt RN CM Post Grad Dip-Comm Health Frances Rogan RN CM B App S M Com Nurs Virginia Schmied RN CM BA MA Hons Aileen Wyllie RN CM BA MHPEd 《Journal of advanced nursing》1997,25(4):719-728
This paper presents the results of a qualitative study conducted by midwife researchers into women's experience of new motherhood. Data were collected using focus groups involving 55 first-time mothers and analysed using grounded theory method. The analysis produced six categories: 'realizing', 'unready', 'drained', 'aloneness', 'loss' and 'working it out'. The core category, 'becoming a mother', integrates all other categories and encapsulates the process of change experienced by women. Also explained are factors mediating the often distressing experience of becoming a mother. The analysis provides a conceptualization of early motherhood enabling the development of strategies for midwives, nurses and others helping women negotiate this challenge. 相似文献