全文获取类型
收费全文 | 118602篇 |
免费 | 7166篇 |
国内免费 | 1580篇 |
专业分类
耳鼻咽喉 | 1575篇 |
儿科学 | 2972篇 |
妇产科学 | 4112篇 |
基础医学 | 18293篇 |
口腔科学 | 3607篇 |
临床医学 | 9267篇 |
内科学 | 21592篇 |
皮肤病学 | 2436篇 |
神经病学 | 8005篇 |
特种医学 | 4022篇 |
外国民族医学 | 3篇 |
外科学 | 16755篇 |
综合类 | 5215篇 |
一般理论 | 34篇 |
预防医学 | 8673篇 |
眼科学 | 2816篇 |
药学 | 10220篇 |
中国医学 | 822篇 |
肿瘤学 | 6929篇 |
出版年
2021年 | 981篇 |
2019年 | 1046篇 |
2018年 | 1611篇 |
2017年 | 1166篇 |
2016年 | 1199篇 |
2015年 | 1445篇 |
2014年 | 1890篇 |
2013年 | 2444篇 |
2012年 | 3546篇 |
2011年 | 3801篇 |
2010年 | 2295篇 |
2009年 | 2051篇 |
2008年 | 3385篇 |
2007年 | 3619篇 |
2006年 | 3600篇 |
2005年 | 3168篇 |
2004年 | 2984篇 |
2003年 | 2776篇 |
2002年 | 2633篇 |
2001年 | 6730篇 |
2000年 | 6921篇 |
1999年 | 5696篇 |
1998年 | 1830篇 |
1997年 | 1377篇 |
1996年 | 935篇 |
1995年 | 862篇 |
1992年 | 3728篇 |
1991年 | 3806篇 |
1990年 | 3549篇 |
1989年 | 3552篇 |
1988年 | 3428篇 |
1987年 | 3277篇 |
1986年 | 3090篇 |
1985年 | 2967篇 |
1984年 | 2048篇 |
1983年 | 1792篇 |
1982年 | 985篇 |
1979年 | 1909篇 |
1978年 | 1184篇 |
1977年 | 986篇 |
1976年 | 918篇 |
1975年 | 1191篇 |
1974年 | 1358篇 |
1973年 | 1413篇 |
1972年 | 1357篇 |
1971年 | 1247篇 |
1970年 | 1137篇 |
1969年 | 1121篇 |
1968年 | 1024篇 |
1967年 | 897篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
171.
A rapid nonsterile short-term assay has been investigated in which percent inhibition of incorporation of the DNA precursor (3H)-thymidine is measured following exposure of tumor cells to the test drugs. To evaluate the usefulness of the short-term assay in providing a rapid reliable assessment of chemotherapeutic response, the short-term assay was compared with the soft agar clonogenic assay. Sensitivity to five anticancer drugs was compared using three human tumor cell lines (epidermoid carcinoma of the oral cavity, pancreatic carcinoma, and bladder carcinoma). The short-term assay produced results that were similar to results of the clonogenic assay in two of the three tumors tested, for three drugs (cis-platin, doxorubicin, and BCNU), but did not detect responses to two antimetabolites (5-FU and MTX) in any tumor. Further studies of this short-term assay should focus on alkylating agents and other nonantimetabolites. 相似文献
172.
Steven Z George Mark D Bishop Joel E Bialosky Giorgio Zeppieri Michael E Robinson 《BMC musculoskeletal disorders》2006,7(1):68
Background
The underlying causes of spinal manipulation hypoalgesia are largely unknown. The beneficial clinical effects were originally theorized to be due to biomechanical changes, but recent research has suggested spinal manipulation may have a direct neurophysiological effect on pain perception through dorsal horn inhibition. This study added to this literature by investigating whether spinal manipulation hypoalgesia was: a) local to anatomical areas innervated by the lumbar spine; b) correlated with psychological variables; c) greater than hypoalgesia from physical activity; and d) different for A-delta and C-fiber mediated pain perception. 相似文献173.
174.
175.
The intercostal hernia of the lung is a very rare extraordinary disease that requires operation because of the complaints
and potential complications. The authors review cases of their operations and analyze the subsequence and treatment. Three
patients have been treated for intercostal lung hernia in our treatment. The causes of this disease were a previous thoracotomy
in one case and fits of coughing in the other two cases. The diagnosis was set up on the grounds of the specific clinical
symptoms, thoracic X-ray and CT scan. The hernia was dissolved with percostal stitches and with the suture of the thoracic
musculature in two cases. Plastic operation of the thoracic wall by implanting a polypropylene surgical mesh (Prolen, Ethicon,
Johnson & Johnson) was performed in the case of the third patient and later in the first two patients due to recrudescence.
In one case the authors were constrained to resect the dystelectasial lung in the hernial sac. The three patients had been
operated five times. Relapse of hernia was detected in two patients, in whom the intercostal space had been reconstructed
with percostal stitches. We did not detect any relapsing in those two patients at 33 and 66 months after the second operation
with mesh implantation. The third patient who got mesh implant immediately did not relapse 12 months after the operation.
Intercostal lung hernia is an indication of operation. A plastic operation of the thoracic wall combined with the implantation
of a surgical mesh is recommended to close the hernial orifice, which is suitable for treating both primary and relapsed hernias.
Recurrence is rare in those patients treated with this method. 相似文献
176.
177.
C. Z. BACHRATI Z. SOMODI E. ENDREFFY T. KALMÁR I. RASKÓ 《Annals of human genetics》1998,62(6):511-520
Duchenne and Becker muscular dystrophies are among the most severe and frequent inherited disorders. Being still incurable, medical treatment is concentrated on the carrier diagnosis of the members of the affected families. Here we report the results of the studies of 151 members of 41 Hungarian families, obtained with multiplex PCR amplification of 18 exons as well as the muscle specific promoter region, and haplotype analysis of two polymorphic (CA)n repeat microsatellite loci in introns 45 and 49 of the dystrophin gene. The analysis of 15 deletion-type families revealed a frequency of new mutations not differing significantly from that in the other regions of Europe. We also compared the allele distributions of the two microsatellites in randomly selected normal individuals and affected family members. The allele distribution of STRP45 shows interesting differences between the two populations. 相似文献
178.
179.
180.
A Lindner Z Braf A Lev J Golomb Z Leib Y Siegel C Servadio 《British journal of urology》1990,65(2):201-203
Local hyperthermia of the prostate was used to treat 72 patients who had an indwelling catheter because of urinary retention caused by benign prostatic hypertrophy. One month after completion of treatment 50% of patients were able to dispense with the catheter and 1 year later 40% remained catheter-free. The best results were achieved in patients who underwent 6 to 10 treatment sessions in conjunction with cyproterone acetate 50 mg tid administered during the treatment period only. 相似文献