全文获取类型
收费全文 | 291篇 |
免费 | 11篇 |
国内免费 | 1篇 |
专业分类
儿科学 | 10篇 |
基础医学 | 41篇 |
口腔科学 | 5篇 |
临床医学 | 28篇 |
内科学 | 39篇 |
皮肤病学 | 5篇 |
神经病学 | 19篇 |
特种医学 | 8篇 |
外科学 | 21篇 |
综合类 | 5篇 |
预防医学 | 79篇 |
眼科学 | 2篇 |
药学 | 20篇 |
肿瘤学 | 21篇 |
出版年
2024年 | 1篇 |
2023年 | 1篇 |
2022年 | 7篇 |
2021年 | 23篇 |
2020年 | 3篇 |
2019年 | 7篇 |
2018年 | 10篇 |
2017年 | 6篇 |
2016年 | 12篇 |
2015年 | 4篇 |
2014年 | 9篇 |
2013年 | 16篇 |
2012年 | 19篇 |
2011年 | 32篇 |
2010年 | 16篇 |
2009年 | 20篇 |
2008年 | 12篇 |
2007年 | 14篇 |
2006年 | 14篇 |
2005年 | 15篇 |
2004年 | 11篇 |
2003年 | 10篇 |
2002年 | 13篇 |
2001年 | 3篇 |
2000年 | 4篇 |
1999年 | 1篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1988年 | 4篇 |
1987年 | 1篇 |
1986年 | 5篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1979年 | 1篇 |
1976年 | 1篇 |
排序方式: 共有303条查询结果,搜索用时 15 毫秒
91.
92.
Patellar metastasis is uncommon. The clinical presentation is often misleading, suggestive of septic arthritis or meniscal disorder after knee trauma. We report the case of a 71-year-old patient who developed knee pain aggravated by movement with pseudo-blockage which was found to be related to a secondary localization of a primary lung cancer. Low blood flow in the patella probably explains why patellar metastasis is so rare. 相似文献
93.
94.
S. Khemir H. Siala H. Azzouz N. Tebib J.L. Dhondt T. Messaoud S. Abdelhak M.F. Ben Dridi N. Kaabachi 《Pathologie-biologie》2012,60(6):e87-e89
Phenylketonuria (PKU) is an autosomal recessive metabolic disorder caused by a deficiency of phenylalanine hydroxylase. To date, more than 530 mutations in the PAH gene have been reported. In Tunisia, this disease seems to be the result of point mutations, few studies have been published about molecular defects of PKU in our country. In this study, we report a novel deletion in exon 6 of two brothers in a Tunisian family after DHPLC analysis and sequencing of the exon 6 of the PAH gene. 相似文献
95.
Fethi Mellouli Imen Ben Mustapha Monia Ben Khaled Habib Besbes Monia Ouederni Najla Mekki Meriem Ben Ali Beya Larguèche Mongia Hachicha Tahar Sfar Neji Gueddiche Siheme Barsaoui Azza Sammoud Khadija Boussetta Saida Ben Becher Ahmed Meherzi Najoua Guandoura Lamia Boughammoura Abdelaziz Harbi Fethi Amri Fethi Bayoudh Najla Ben Jaballah Neji Tebib Asma Bouaziz Abdelmajid Mahfoudh Hajer Aloulou Lamia Ben Mansour Imen Chabchoub Raoudha Boussoffara Jalel Chemli Jihène Bouguila Saida Hassayoun Saber Hammami Zakia Habboul Agnès Hamzaoui Jamel Ammar Mohamed-Ridha Barbouche Mohamed Bejaoui 《Journal of clinical immunology》2015,35(8):745-753
96.
This study is a comparison of the treatments used in 36 patients suffering from pyonephrosis. The patients were subdivided in two groups: cases having undergone previous percutaneous drainage; and cases having undergone primary nephrectomy. These latter cases presented a high complication rate. We believe that preliminary drainage by percutaneous nephrostomy, constitutes the procedure of choice, when ever possible, to drain the kidney and prepare the patient for nephrectomy. 相似文献
97.
We report a rare case of hydatid cyst presenting as a 13 cm cyst in the wall of the lower mediastinal portion of the thoracic aorta associated with splenic and peritoneal cysts. The diagnostic problems are discussed. 相似文献
98.
A procedure to standardize the position of an esophageal catheter (eso-cat) tip, used to measure intrathoracic pressure, was tested in ten healthy Dutch Friesians. The cattle were in normal condition with body weights (BW) between 52 and 670 kg and thoracic perimeters (TP) between 80 and 210 cm. The position of the neck and head was standardized. The eso-cat was introduced via the nose into the thoracic portion of the esophagus. The distance between the nares and the eso-cat tip (Lcat), which was positioned between the crossing point with the aorta and the caudal mediastinal lymph nodes, was measured for each animal. The regression equation, calculated between the Lcat and the BW and TP was, respectively: Lcat (cm) = 65 + 0.115 x BW (kg) (r2 = 0.99) and Lcat (cm) = 22 + 0.535 x TP (cm) (r2 = 0.97). The corresponding residual standard deviations were respectively 2.52 and 4.37 cm. The multiple and curvi-linear regression equation did not give a significantly better fit of the data. 相似文献
99.
Background
Peters Plus syndrome (MIM 261540) is a rare autosomal recessive condition characterized by ocular defects (typically Peters anomaly) and other systemic major/minor abnormalities. Mutations in the B3GALTL gene encoding the β-1,3-glucosyltransferase have been found in virtually all patients with typical Peters Plus syndrome.Case Presentation
We report here a female patient with severe manifestations of Peters Plus syndrome including facial dysmorphism and bilateral corneal opacity associated with left renal pyelo-calicial dilatation and sexual ambiguity. Total sequencing of the B3GALTL gene revealed no mutation in the patient.Conclusion
To our knowledge, sexual ambiguity has not previously been reported in Peters Plus syndrome so far, and renal malformation is also apparently rare in the syndrome. 相似文献100.
Mahfoudh N Siala M Rihl M Kammoun A Frikha F Fourati H Younes M Gdoura R Gaddour L Hakim F Bahloul Z Baklouti S Bargaoui N Sellami S Hammami A Makni H 《Clinical rheumatology》2011,30(8):1069-1073
The aim of this study is to investigate the association of HLA-A, B and HLA-DR gene expression and to assess an association of additional HLA antigens besides HLA-B27 in south Tunisian patients with spondyloarthritis (SpA). Eighty-five patients diagnosed with ankylosing spondylitis (AS, n=68) and reactive arthrithis (ReA, n=17) were selected and compared with 100 healthy controls (HC). HLA class I antigens were typed serologically using microlymphocytotoxicity technique. HLA-DRB1* alleles were studied by polymerase chain reaction amplification with sequence-specific primers. The significance of differences between patients and controls was tested by chi-square analysis. We found significantly increased frequencies of HLA-A3 (30.6%; pC=0.04; OR=2.95), HLA-B27 (62.35%; pC=4.10(-17), OR=53.55), and HLA-DRB1*15 (17.2%; pC=0.026; RR=2.58) alleles in SpA patients compared to HC. The most frequent and strongest association was observed for HLA-B27 in AS (pC=6.6 ×10(-16), OR=52.23). When AS and ReA patients were analysed separately, HLA-DRB1*15 and HLA-A3 were increased only in AS (pC=0.01, OR=2.99 and pC=0.03, OR=3.14, respectively). In ReA patients, HLA-DRB1*04 (p=0.033, pC=NS, OR=2.89) was found to be the most common allele. By analysing the HLA-B27-negative subgroup, HLA-A3 and HLA-DRB1*15 expression was found to be dependent on the presence of HLA-B27. HLA-B27 expression was higher in male (45/53; 85%) as compared to female (8/53; 15%) patients (p=0.03). Apart from HLA-B27, HLA-A3 and HLA-DRB1*15 are the MHC class I and II alleles found most frequent in Tunisian patients with AS, whereas HLA-DRB1*04 was found most frequent in ReA patients. HLA-B27 is more frequent in male than in female patients. 相似文献