全文获取类型
收费全文 | 81836篇 |
免费 | 7811篇 |
国内免费 | 6443篇 |
专业分类
耳鼻咽喉 | 712篇 |
儿科学 | 836篇 |
妇产科学 | 896篇 |
基础医学 | 9622篇 |
口腔科学 | 1293篇 |
临床医学 | 11289篇 |
内科学 | 12196篇 |
皮肤病学 | 687篇 |
神经病学 | 4481篇 |
特种医学 | 3016篇 |
外国民族医学 | 65篇 |
外科学 | 8009篇 |
综合类 | 14148篇 |
现状与发展 | 12篇 |
一般理论 | 6篇 |
预防医学 | 5732篇 |
眼科学 | 2044篇 |
药学 | 8894篇 |
86篇 | |
中国医学 | 4960篇 |
肿瘤学 | 7106篇 |
出版年
2024年 | 284篇 |
2023年 | 1389篇 |
2022年 | 3453篇 |
2021年 | 4253篇 |
2020年 | 3244篇 |
2019年 | 2829篇 |
2018年 | 2981篇 |
2017年 | 2661篇 |
2016年 | 2519篇 |
2015年 | 3891篇 |
2014年 | 4535篇 |
2013年 | 3949篇 |
2012年 | 5942篇 |
2011年 | 6451篇 |
2010年 | 3985篇 |
2009年 | 3069篇 |
2008年 | 4096篇 |
2007年 | 4110篇 |
2006年 | 4153篇 |
2005年 | 3943篇 |
2004年 | 2924篇 |
2003年 | 2978篇 |
2002年 | 2678篇 |
2001年 | 2295篇 |
2000年 | 2084篇 |
1999年 | 2082篇 |
1998年 | 1420篇 |
1997年 | 1318篇 |
1996年 | 973篇 |
1995年 | 957篇 |
1994年 | 791篇 |
1993年 | 454篇 |
1992年 | 620篇 |
1991年 | 511篇 |
1990年 | 414篇 |
1989年 | 414篇 |
1988年 | 319篇 |
1987年 | 272篇 |
1986年 | 236篇 |
1985年 | 192篇 |
1984年 | 89篇 |
1983年 | 69篇 |
1982年 | 45篇 |
1981年 | 43篇 |
1980年 | 35篇 |
1979年 | 30篇 |
1978年 | 14篇 |
1974年 | 9篇 |
1971年 | 10篇 |
1970年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
Viral markers were studied in 79 cases of viral hepatitis with hepatic failure. The results were shown as follows: 8 cases were positive for anti-HAV IgM (10.12%); 76 cases positive for HBsAg or anti-HBc IgM (96.20%) and 41 cases positive for anti-HCV antibodies (51.89%). Among those with anti-HCV positive, 35 cases were co-infected with HBV, 5 cases with HAV and/or HCV, only one was infected with HCV alone 2 cases were HD-Ag positive (2.52%) and one not identified (1.27%). With the reference of clinical findings, patients co-infected with HBV/HCV or anti-HBc IgM positive were more critical and usually entail higher mortality. In cases with HCV co-infections, the positive HBV replication markers seems to be reduced. Hepatic failure without HBV replicative markers had a high rate of hepatic coma as well as poor outcome. 相似文献
52.
目的:研究中国汉族群体中α艾杜糖苷酶基因D4S111位点的遗传多态性。方法:采用扩增片段长度多态性(AmpFLP)分析技术,检测了广州地区汉族无血缘关系健康个体97名。结果:D4S111位点,在97名无关个体中发现5个等位基因和9种基因型,等位基因片段长度为830~510bp,基因频率为00052~03608,PIC为05966,杂合性为078。结论:中国汉族群体中D4S111位点具有高度多态性,并与其它种族间存在差异性。 相似文献
53.
应用单链构象多态性分析多聚酶链反应EB染色法(PCR-SSCP-EB)对40例肺癌组织标本的P53基因序列5~8外显子突变进行分析,同时应用PCR方法检测上述标本及18例肺良性疾病组织标本中HPV16、18型DNA相关序列,旨在分析二者在肺鳞癌发病中的作用及相互关系,并就肺鳞癌与P53基因结构和功能异常的关系进行初步探讨。 相似文献
54.
55.
56.
目的 了解本社区高血压患者的危险因素现状,探讨干预对策。方法 采用分层整群抽样的方法,随机抽取社区4个里委2级、3级高血压患者402例作为研究对象,收集各项危险因素如性别、年龄、血脂、血糖、吸烟、饮食、体育锻炼、体重等,并进行统计分析。结果402例高血压患者1年内进行所有相关辅助检查者有14例,占3.48%;1年内进行相关辅助检查一项者306例,占76.12%。饮食控制及进行体育锻炼有300例,占74.43%;吸烟62例,占15.42%。结论 高血压患者对饮食控制及体育锻炼、吸烟有害的知晓率明显提高,而对相关辅助检查认识不足。 相似文献
57.
张宇 文天夫 陈哲宇 严律南 梁冠林 李国 张显华 冉顺 廖志学 ZHANG Yu WEN Tian-fu CHEN Zhe-yu YAN Lü-nan LIANG Guan-lin LI Guo ZHANG Xian-hua RAN Shun LIAO Zhi-xue 《中华普通外科杂志》2004,24(1):470-472
Objective To observe changes of hepatic hemodynamics and hepatic functional reserve after splenectomy and periesophagogastric devascularization. Methods From July 2006 to August 2007, thirty patients with portal hypertension caused by hepatitis B cirrhosis underwent splenectomy and periesophagogastric devascuiarization. The PVPG (portal venous pressure gradient) was measured by inductor continually during operation. The HAF (hepatic artery flow), PVF (portal venours flow) and hepatic arterial RI(resistant index) were measured with Doppler sonography. The EHBF(effective hepatic blood flow) and ICGR15 (indocyaninegreen retention rate at 15 minutes) were obtained respectively by indocyaninegreen clearance test before and after the operation. Results PVPG after laparotomy (19±4) mm Hg, ligating the splenic artery(14±4) mm Hg, splenectomy(14±3)mm Hg and periesophagogastric devascularization (12±4) mm Hg showed a tendency to decrease progressively. The PVF decreased [from (42±14) ml/s to (16±8) ml/s] and HAF increased in compensation after operation. The EHBF increased [from (0.48±0.10) L/min to (0.56±0.10) L/min], and the ICGR15 decreased (from 23%±8% to 18%±4%) postoperatively. Conclusion After splenectomy and periesophagogastric devascularization, the hepatic functional reserve improves at least in a short term notwithstanding the decrease of PVPG and PVF. 相似文献
58.
59.
目的 探讨老年人肱骨近端二部分和三部分移位骨折的手术治疗方法。方法 回顾性分析19例老年肱骨近端二部分和三部分移位骨折患者的临床资料,其中二部分骨折13例、三部分骨折6例,采用切开复位,肱骨近端解剖钢板固定治疗。结果 二部分骨折术后优良率为76.9%,未出现骨折不愈合及肱骨头坏死;三部分骨折术后优良率为66.7%,肱骨头坏死率16.7%。结论 老年人肱骨近端二部分和三部分骨折应尽量采用有限切开复位,选择肱骨近端解剖钢板固定。 相似文献
60.
The blood–brain barrier (BBB) is an immense neurovascular interface. In neurodegenerative, ischemic, and traumatic disorders of the central nervous system (CNS), the BBB may hinder the delivery of many therapeutic peptides and proteins to the brain and spinal cord. Fortunately, the mistaken dogma that peptides and proteins do not cross the BBB has been corrected during the past two decades by the accumulating evidence that peptides and proteins in the periphery exert potent effects in the CNS. Not only can peptides and proteins serve as carriers for selective therapeutic agents, but they themselves may directly cross the BBB after delivery into the bloodstream. Their passage may be mediated by simple diffusion or specific transport, both of which can be affected by interactions in the blood compartment (outside the BBB) and within the endothelial cells (at the BBB level). Although the majority of current delivery strategies focuses on modification of the molecule to be delivered, understanding the mechanisms of transport will eventually facilitate regulation of the BBB directly. We review the different aspects of interactions and discuss recent advances in the cell biology of peptide/protein transport across the BBB. Better understanding of the nature and regulation of the transport systems at the BBB will provide a new direction to enhance the interactions of peripheral peptides and proteins with the CNS. 相似文献