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B. T. Schleenvoigt M. Gajda M. Baier T. Groten H. Oppel-Heuchel M. O. Grimm W. Pfister J. Richter M. W. Pletz 《Infection》2014,42(6):1061-1064
Schistosomiasis is a widespread helminthic infection which sometimes may affect travelers to endemic areas. We report on a case of urogenital and placental schistosomiasis in a 28-year-old German woman who had been exposed to schistosomiasis in Lake Malawi one year earlier. She experienced painless macrohaematuria in her 21st week of pregnancy. Cystoscopy revealed vesical lesions typical for urogenital schistosomiasis. Histopathology confirmed ova of Schistosoma (S.) haematobium. The patient was treated with praziquantel 40 mg/kg/body weight/day for 3 days. After 285 days of gestation and 18 weeks post treatment, the patient delivered a healthy girl. Histopathology of placenta revealed eggs of S. haematobium in placental stroma. The infant proved negative for anti-Schistosoma spp. antibodies at the age of 15 months. This is the first report on placental schistosomiasis since 1980 and the first case occurring in a traveler. 相似文献
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Tetrapyrrole biosynthetic enzyme protoporphyrinogen IX oxidase 1 is required for plastid RNA editing
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Encoding of nested levels of acoustic regularity in hierarchically organized areas of the human auditory cortex
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Marc Recasens Sabine Grimm Andreas Wollbrink Christo Pantev Carles Escera 《Human brain mapping》2014,35(11):5701-5716
Our auditory system is able to encode acoustic regularity of growing levels of complexity to model and predict incoming events. Recent evidence suggests that early indices of deviance detection in the time range of the middle‐latency responses (MLR) precede the mismatch negativity (MMN), a well‐established error response associated with deviance detection. While studies suggest that only the MMN, but not early deviance‐related MLR, underlie complex regularity levels, it is not clear whether these two mechanisms interplay during scene analysis by encoding nested levels of acoustic regularity, and whether neuronal sources underlying local and global deviations are hierarchically organized. We registered magnetoencephalographic evoked fields to rapidly presented four‐tone local sequences containing a frequency change. Temporally integrated local events, in turn, defined global regularities, which were infrequently violated by a tone repetition. A global magnetic mismatch negativity (MMNm) was obtained at 140–220 ms when breaking the global regularity, but no deviance‐related effects were shown in early latencies. Conversely, Nbm (45–55 ms) and Pbm (60–75 ms) deflections of the MLR, and an earlier MMNm response at 120–160 ms, responded to local violations. Distinct neuronal generators in the auditory cortex underlay the processing of local and global regularity violations, suggesting that nested levels of complexity of auditory object representations are represented in separated cortical areas. Our results suggest that the different processing stages and anatomical areas involved in the encoding of auditory representations, and the subsequent detection of its violations, are hierarchically organized in the human auditory cortex. Hum Brain Mapp 35:5701–5716, 2014. © 2014 Wiley Periodicals, Inc. 相似文献
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Hélène Louis-Dit-Picard Ilektra Kouranti Chloé Rafael Irmine Loisel-Ferreira Maria Chavez-Canales Waed Abdel-Khalek Eduardo R. Argaiz Stéphanie Baron Sarah Vacle Tiffany Migeon Richard Coleman Marcio Do Cruzeiro Marguerite Hureaux Nirubiah Thurairajasingam Stéphane Decramer Xavier Girerd Kevin O’Shaugnessy Paolo Mulatero Gwena?lle Roussey Ivan Tack Robert Unwin Rosa Vargas-Poussou Olivier Staub Richard Grimm Paul A. Welling Gerardo Gamba Eric Clauser Juliette Hadchouel Xavier Jeunemaitre 《The Journal of clinical investigation》2020,130(12):6379
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Matthew T. Whitehead Asim F. Choudhri John Grimm Marvin D. Nelson 《Pediatric radiology》2014,44(7):849-856