全文获取类型
收费全文 | 1657篇 |
免费 | 153篇 |
国内免费 | 49篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 108篇 |
妇产科学 | 17篇 |
基础医学 | 126篇 |
口腔科学 | 45篇 |
临床医学 | 117篇 |
内科学 | 375篇 |
皮肤病学 | 157篇 |
神经病学 | 107篇 |
特种医学 | 200篇 |
外科学 | 167篇 |
综合类 | 100篇 |
预防医学 | 82篇 |
眼科学 | 86篇 |
药学 | 92篇 |
中国医学 | 3篇 |
肿瘤学 | 67篇 |
出版年
2023年 | 17篇 |
2022年 | 13篇 |
2021年 | 25篇 |
2020年 | 26篇 |
2018年 | 24篇 |
2017年 | 42篇 |
2016年 | 39篇 |
2015年 | 33篇 |
2014年 | 65篇 |
2013年 | 80篇 |
2012年 | 33篇 |
2011年 | 40篇 |
2010年 | 68篇 |
2009年 | 75篇 |
2008年 | 37篇 |
2007年 | 74篇 |
2006年 | 42篇 |
2005年 | 35篇 |
2004年 | 33篇 |
2003年 | 22篇 |
2002年 | 24篇 |
2001年 | 46篇 |
2000年 | 29篇 |
1999年 | 27篇 |
1998年 | 85篇 |
1997年 | 66篇 |
1996年 | 66篇 |
1995年 | 54篇 |
1994年 | 46篇 |
1993年 | 44篇 |
1992年 | 25篇 |
1990年 | 28篇 |
1989年 | 34篇 |
1988年 | 34篇 |
1987年 | 27篇 |
1986年 | 30篇 |
1985年 | 29篇 |
1984年 | 18篇 |
1983年 | 23篇 |
1982年 | 22篇 |
1981年 | 16篇 |
1980年 | 19篇 |
1979年 | 22篇 |
1978年 | 26篇 |
1977年 | 19篇 |
1976年 | 20篇 |
1975年 | 27篇 |
1974年 | 23篇 |
1973年 | 22篇 |
1968年 | 11篇 |
排序方式: 共有1859条查询结果,搜索用时 0 毫秒
61.
Procedural variation in the performance of primary percutaneous coronary intervention for ST‐elevation myocardial infarction: A SCAI‐based survey study of US interventional cardiologists 下载免费PDF全文
Austin Chiang MD Hemal Gada MD MBA Susheel K. Kodali MD Michael S. Lee MD Allen Jeremias MD Duane S. Pinto MD MPH Sripal Bangalore MD MHA Robert W. Yeh MD MSc Timothy D. Henry MD Georgina Lopez‐Cruz BS MSHA Roxana Mehran MD Ajay J. Kirtane MD SM 《Catheterization and cardiovascular interventions》2014,83(5):721-726
62.
Lin Zhang Joseph JY Sung Jun Yu Siew C Ng Sunny H Wong Chi H Cho Simon SM Ng Francis KL Chan William KK Wu 《The Journal of pathology》2014,233(2):103-112
Helicobacter pylori and Epstein–Barr virus (EBV) account for roughly 80% and 10%, respectively, of gastric carcinomas worldwide. Autophagy is an evolutionarily conserved and intricately regulated cellular process that involves the sequestration of cytoplasmic proteins and organelles into double‐membrane autophagosomes that eventually fuse with lysosomes for degradation of the engulfed content. Emerging evidence indicates that xenophagy, a form of selective autophagy, plays a crucial role in the pathogenesis of H. pylori‐ and EBV‐induced gastric cancer. Xenophagy specifically recognizes intracellular H. pylori and EBV and physically targets these pathogens to the autophagosomal–lysosomal pathway for degradation. In this connection, H. pylori or EBV‐induced dysregulation of autophagy may be causally linked to gastric tumourigenesis and therefore can be exploited as therapeutic targets. This review will discuss how H. pylori and EBV infection activate autophagy and how these pathogens evade recognition and degradation by the autophagic pathway. Elucidating the molecular aspects of H. pylori‐ and EBV‐induced autophagy will help us better understand the pathogenesis of gastric cancer and promote the development of autophagy modulators as antimicrobial agents. Published by John Wiley & Sons, Ltd 相似文献
63.
64.
65.
66.
Allen-Vercoe E Reid G Viner N Gloor GB Hota S Kim P Lee C O'Doherty K Vanner SJ Weese JS Petrof EO 《Journal canadien de gastroenterologie》2012,26(7):457-462
A working group from across Canada comprised of clinician and basic scientists, epidemiologists, ethicists, Health Canada regulatory authorities and representatives of major funding agencies (Canadian Institutes of Health Research and the Crohn's and Colitis Foundation of Canada) met to review the current experience with fecal microbial therapy and to identify the key areas of study required to move this field forward. The report highlights the promise of fecal microbial therapy and related synthetic stool therapy (together called 'microbial ecosystems therapeutics') for the treatment of Clostridium difficile colitis and, possibly, other disorders. It identifies pressing clinical issues that need to be addressed as well as social, ethical and regulatory barriers to the use of these important therapies. 相似文献
67.
Arne Fischmann Patricia Hafner Monika Gloor Maurice Schmid Andrea Klein Urs Pohlman Tanja Waltz Rocio Gonzalez Tanja Haas Oliver Bieri Dirk Fischer 《Journal of neurology》2013,260(4):969-974
The purpose of this ethics approved trial was to correlate quantitative MRI with functional abilities in both ambulant and non-ambulant Duchenne muscular dystrophy (DMD). Twenty patients with genetically confirmed DMD were recruited. Physical assessment was performed using the motor function measurement (MFM) scale. Axial 3T MRI scans of the thighs were acquired using T1-weighted in- and opposed-phase images (TR = 20 ms, TE1 = 2.45 ms, TE2 = 3.68 ms, flip angle = 15°) to calculate the relative fat fraction according to the two-point Dixon method in the knee extensors, flexors, and adductor muscles. The average MFM was 65.3 % and correlated negatively to age (r 2 = 0.60). Overall mean fat fraction correlated positively to age (r 2 = 0.51–0.64). An average of 5 % increase in mean fat fraction per year was calculated. Mean fat fraction of the quadriceps showed a high negative correlation (r 2 = 0.93) to the D1 (standing position and transfers) component of the MFM. A cutoff for mean fat fraction of 50 % predicted loss of ambulation with a sensitivity of 100 % and a specificity of 91 %. Therefore, quantitative muscle MRI seems to be a promising endpoint for short clinical trials evaluating the effect of newer treatments on the time of loss of ambulation in DMD. 相似文献
68.
Marwan SM Al-Nimer 《World journal of diabetes》2022,13(5):417-419
Hyperandrogenism and hyperinsulinemia have resulted from dysfunction of the theca cell of the ovary and adipose tissue and each one potentiates the other in patients with androgen excess disorders e.g., polycystic ovary disease and idiopathic hirsutism. Possible external and/or internal triggers can produce such cellular dysfunction. There is evidence that sodium valproate acts as a trigger of cellular dysfunction and produces both hyperinsulinemia and hyperandrogenism. Therefore, the elimination of these triggers can help the patients to recover from hyperinsulinemia, insulin resistance and hyperandrogenism. 相似文献
69.
70.
Ilias Nikolakopoulos MD James W. Choi MD Khaldoon Alaswad MD Jaikirshan J. Khatri MD Oleg Krestyaninov MD Dmitrii Khelimskii MD Robert W. Yeh MD PhD Farouc A. Jaffer MD PhD Catalin Toma MD Mitul Patel MD Ehtisham Mahmud MD Nicholas J. Lembo MD Manish Parikh MD Ajay J. Kirtane MD SM Ziad A. Ali MD Fotis Gkargkoulas MD Barry Uretsky MD Abdul M. Sheikh MD Evangelia Vemmou MD Iosif Xenogiannis MD Bavana V. Rangan BDS MPH Santiago Garcia MD Shuaib Abdullah MD Subhash Banerjee MD M. Nicholas Burke MD Emmanouil S. Brilakis MD PhD Dimitri Karmpaliotis MD PhD 《Catheterization and cardiovascular interventions》2021,97(4):658-667