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Giuseppe Carrà Alessandro Schivalocchi Francesco Bartoli Daniele Carretta Giulia Brambilla 《Substance Abuse》2015,36(4):445-452
Background: Binge drinking is common among young people but often relevant risk factors are not recognized. eHealth apps, attractive for young people, may be useful to enhance awareness of this problem. We aimed at developing a current risk estimation model for binge drinking, incorporated into an eHealth app—D-ARIANNA (Digital-Alcohol RIsk Alertness Notifying Network for Adolescents and young adults)—for young people. Methods: A longitudinal approach with phase 1 (risk estimation), phase 2 (design), and phase 3 (feasibility) was followed. Risk/protective factors identified from the literature were used to develop a current risk estimation model for binge drinking. Relevant odds ratios were subsequently pooled through meta-analytic techniques with a random-effects model, deriving weighted estimates to be introduced in a final model. A set of questions, matching identified risk factors, were nested in a questionnaire and assessed for wording, content, and acceptability in focus groups involving 110 adolescents and young adults. Results: Ten risk factors (5 modifiable) and 2 protective factors showed significant associations with binge drinking and were included in the model. Their weighted coefficients ranged between ?0.71 (school proficiency) and 1.90 (cannabis use). The model, nested in an eHealth app questionnaire, provides in percent an overall current risk score, accompanied by appropriate images. Factors that mostly contribute are shown in summary messages. Minor changes have been realized after focus groups review. Most of the subjects (74%) regarded the eHealth app as helpful to assess binge drinking risk. Conclusions: We could produce an evidence-based eHealth app for young people, evaluating current risk for binge drinking. Its effectiveness will be tested in a large trial. 相似文献
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Vynckier Pieter Ferrannini Giulia Rydén Lars Tokgözoğlu Lale Bruthans Jan Kotseva Kornelia Wood David De Backer Tine Gevaert Sofie De Bacquer Dirk De Smedt Delphine 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》2021,35(4):801-808
Cardiovascular Drugs and Therapy - This study is aimed at investigating gender differences in the medical management of patients with coronary heart disease (CHD). Analyses were based on the ESC... 相似文献
95.
Alberto Raiteri Alessandro Granito Alice Giamperoli Teresa Catenaro Giulia Negrini Francesco Tovoli 《World journal of gastroenterology : WJG》2022,28(1):154-175
BACKGROUND Wheat and other gluten-containing grains are widely consumed,providing approximately 50%of the caloric intake in both industrialised and developing countries.The widespread diffusion of gluten-containing diets has rapidly led to a sharp increase in celiac disease prevalence.This condition was thought to be very rare outside Europe and relatively ignored by health professionals and the global media.However,in recent years,the discovery of important diagnostic and pathogenic milestones has led to the emergence of celiac disease(CD)from obscurity to global prominence.These modifications have prompted experts worldwide to identify effective strategies for the diagnosis and follow-up of CD.Different scientific societies,mainly from Europe and America,have proposed guidelines based on CD's most recent evidence.AIM To identify the most recent scientific guidelines on CD,aiming to find and critically analyse the main differences.METHODS We performed a database search on PubMed selecting papers published between January 2010 and January 2021 in the English language.PubMed was lastly accessed on 1 March 2021.RESULTS We distinguished guidelines from 7 different scientific societies whose reputation is worldwide recognized and representative of the clinical practice in different geographical regions.Differences were noted in the possibility of a no-biopsy diagnosis,HLA testing,follow-up protocols,and procedures.CONCLUSION We found a relatively high concordance between the guidelines for CD.Important modifications have occurred in the last years,especially about the possibility of a no-biopsy diagnosis in children.Other modifications are expected in the next future and will probably involve the extension of the non-invasive diagnosis to the adult population and the follow-up modalities. 相似文献
96.
Mandoli Giulia Elena Borrelli Chiara Cameli Matteo Mondillo Sergio Ghiadoni Lorenzo Taddei Claudia Passino Claudio Emdin Michele Giannoni Alberto 《Heart failure reviews》2022,27(5):1869-1881
Heart Failure Reviews - Obstructive (OA) and central apneas (CA) are highly prevalent breathing disorders that have a negative impact on cardiac structure and function; while OA promote the... 相似文献
97.
Adriano N. Kochi MD MSc Massimo Moltrasio MD Fabrizio Tundo MD PhD Stefania Riva MD Ciro Ascione MD Maria A. Dessanai MD Francesca Pizzamiglio MD Giulia Vettor MD Selene Cellucci CCP Alessio Gasperetti MD Claudio Tondo MD PhD Gaetano Fassini MD 《Journal of cardiovascular electrophysiology》2021,32(3):588-594
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Laura Di Domenico Chiara E Sabbatini Giulia Pullano Daniel Lvy-Bruhl Vittoria Colizza 《Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin》2021,26(15)
Following the spread of the SARS-CoV-2 B.1.1.7 variant, social distancing was strengthened in France in January 2021. Using a two-strain mathematical model calibrated on genomic surveillance, we estimated that curfew measures allowed hospitalisations to plateau by decreasing transmission of the historical strains while B.1.1.7 continued to grow. School holidays appear to have further slowed down progression in February. Without progressively strengthened social distancing, a rapid surge of hospitalisations is expected, despite the foreseen increase in vaccination rhythm. 相似文献
100.
Pietro Palmisano MD Matteo Ziacchi MD Ernesto Ammendola MD Antonio D'Onofrio MD Gabriele Dell'Era MD Mattia Laffi MD Mauro Biffi MD Gerardo Nigro MD PhD Walter Bianchi MD Eleonora Prenna MD Andrea Angeletti MD Alessandro Guido MD Giulia Stronati MD Germano Gaggioli MD Antonio Dello Russo MD Michele Accogli MD Federico Guerra MD Italian Association of Arrhythmology Cardiac Pacing 《Journal of cardiovascular electrophysiology》2021,32(6):1712-1723