全文获取类型
收费全文 | 3654篇 |
免费 | 189篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 76篇 |
儿科学 | 69篇 |
妇产科学 | 80篇 |
基础医学 | 472篇 |
口腔科学 | 67篇 |
临床医学 | 342篇 |
内科学 | 903篇 |
皮肤病学 | 24篇 |
神经病学 | 639篇 |
特种医学 | 118篇 |
外科学 | 387篇 |
综合类 | 8篇 |
一般理论 | 2篇 |
预防医学 | 166篇 |
眼科学 | 35篇 |
药学 | 212篇 |
中国医学 | 15篇 |
肿瘤学 | 252篇 |
出版年
2023年 | 26篇 |
2022年 | 44篇 |
2021年 | 91篇 |
2020年 | 60篇 |
2019年 | 83篇 |
2018年 | 102篇 |
2017年 | 74篇 |
2016年 | 109篇 |
2015年 | 100篇 |
2014年 | 148篇 |
2013年 | 182篇 |
2012年 | 276篇 |
2011年 | 241篇 |
2010年 | 152篇 |
2009年 | 144篇 |
2008年 | 251篇 |
2007年 | 247篇 |
2006年 | 240篇 |
2005年 | 254篇 |
2004年 | 223篇 |
2003年 | 196篇 |
2002年 | 194篇 |
2001年 | 33篇 |
2000年 | 19篇 |
1999年 | 27篇 |
1998年 | 56篇 |
1997年 | 30篇 |
1996年 | 16篇 |
1995年 | 32篇 |
1994年 | 19篇 |
1993年 | 19篇 |
1992年 | 15篇 |
1991年 | 9篇 |
1990年 | 16篇 |
1989年 | 12篇 |
1988年 | 8篇 |
1987年 | 10篇 |
1986年 | 11篇 |
1985年 | 12篇 |
1984年 | 13篇 |
1983年 | 7篇 |
1982年 | 15篇 |
1981年 | 5篇 |
1980年 | 9篇 |
1979年 | 5篇 |
1978年 | 3篇 |
1976年 | 3篇 |
1974年 | 8篇 |
1973年 | 4篇 |
1970年 | 4篇 |
排序方式: 共有3867条查询结果,搜索用时 15 毫秒
61.
Andrea Grosso Lorena Charrier Emanuela Lovato Claudio Panico Cesare Mariotti Giancarlo Dapavo Roberto Chiuminatto Roberta Siliquini Maria Michela Gianino 《International ophthalmology》2014,34(2):217-223
Small-gauge vitreoretinal techniques have been shown to be safe and effective in the management of a wide spectrum of vitreoretinal diseases. However, the costs of the new technologies may represent a critical issue for national health systems. The aim of the study is to plan a Health Technology Assessment (HTA) by performing a comparative analysis between the 23- and 25-gauge techniques in the management of macular diseases (epiretinal membranes, macular holes, vitreo-macular traction syndrome). In this prospective study, 45–80-year-old patients undergoing vitrectomy surgery for macular disease were enrolled at the Torino Eye Hospital. In the HTA model we assessed the safety, clinical effectiveness, and cost and financial evaluation of 23-gauge compared with 25-gauge vitrectomies. Fifty patients entered the study; 14 patients underwent 23-gauge vitrectomy and 36 underwent 25-gauge vitrectomy. There was no statistically significant difference in post-operative visual acuity at 1 year between the two groups. No cases of retinal detachment or endophtalmitis were registered at 1-year follow-up. The 23-gauge technique was slightly more expensive than the 25-gauge: the total surgical costs were EUR1217.70 versus EUR1164.84 (p = 0.351). We provide a financial comparison between new vitreoretinal procedures recently introduced in the market and reimbursed by the Italian National Health System and we also stimulate a critical debate about the expensive technocratic model of medicine. 相似文献
62.
63.
64.
65.
66.
67.
68.
Piccoli M Trambaiolo P Salustri A Cerquetani E Posteraro A Pastena G Amici E Papetti F Marincola E La Carruba S Gambelli G 《Chest》2005,128(5):3413-3420
OBJECTIVES: The aim of this study was to assess the potential value of hand-carried ultrasound (HCU) devices in the diagnosis and follow-up of patients with pleural effusion (PE) after cardiac surgery. METHODS: Seventy consecutive patients were evaluated at bedside early after cardiac surgery, in the upright sitting position, using an HCU device on hospital admission and every 3 days until hospital discharge. The posterior chest wall was scanned along the paravertebral, scapular, and posterior axillary lines. For each hemithorax, an effusion index was derived as the sum of the intercostal spaces between the lower and upper limits of the PE along the lines of scanning, divided by 3. A standard chest radiograph was performed in all patients on hospital admission and at hospital discharge, and was qualitatively scored (0, absent; 1, small; 2, large PE). The findings of the HCU device and radiograph were compared using kappa statistics and the Kruskal-Wallis test. RESULTS: A chest ultrasound was feasible in all patients (mean [+/- SD] time, 5 +/- 2 min). Compared with the chest ultrasound, a physical examination showed a sensitivity of 69% and a specificity of 77%. On hospital admission, the HCU device detected a PE in 72 of 140 hemithoraxes. Agreement with the finding of the radiograph was 76% (kappa = 0.52). In 15 hemithoraxes, the HCU device revealed a PE that had not been diagnosed using the radiograph. Conversely, in 18 hemithoraxes a PE that had been diagnosed with a radiograph was not confirmed by the HCU device. The correlation between ultrasound and radiographic scores was statistically significant (p < 0.001). At hospital discharge, a PE was present in 31 of 140 hemithoraxes according to the findings of the HCU device, and in 38 of 140 hemithoraxes according to the findings of the radiograph (agreement, 78%; kappa = 0.44). CONCLUSIONS: In patients early after cardiac surgery, HCU devices allow rapid PE detection and improve the clinical diagnosis. Compared to a radiograph, this method offers the unique advantage of the bedside evaluation of patients without the need for radiation exposure. 相似文献
69.
70.
Vignali L Saia F Manari A Santarelli A Rubboli A Varani E Piovaccari G Menozzi A Percoco G Benassi A Rusticali G Marzaroli P Guastaroba P Grilli R Maresta A Marzocchi A 《The American journal of cardiology》2008,101(7):947-952
Percutaneous revascularization of saphenous vein grafts (SVGs) remains a challenging task. Drug-eluting stents (DESs) have been shown to decrease the incidence of restenosis in de novo native coronary artery lesions. However, their clinical value in SVGs remains to be established. We compared long-term clinical outcomes of percutaneous coronary intervention with DESs and bare metal stents (BMSs) for de novo lesions in SVGs. In a large prospective, multicenter registry, 360 patients underwent stenting of a de novo lesion in SVGs using BMSs (288 patients) or DESs (72 patients). Incidence of major adverse cardiac events (MACEs), including all-cause mortality, reinfarction, and target vessel revascularization, was recorded at a 12-month follow-up. Compared with the DES group, patients receiving BMSs were more likely to be men, to have chronic renal insufficiency or higher Charlson scores, but less likely to have undergone previous percutaneous coronary intervention. Incidence of MACEs at 12-month follow-up was similar in the 2 groups (17.8% in DES group vs 20.3% in BMS group, respectively, p = 0.460). Cox regression analysis identified age, chronic renal failure, cardiogenic shock at presentation, and ostial location of stenosis as independent predictors of long-term MACEs. In conclusion, our data suggest that rates of 12-month MACEs associated with the use of DESs and BMSs are similar in patients undergoing treatment of de novo lesions in SVGs. 相似文献