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41.
Lauren J. Breen Regina Szylit Kathleen R. Gilbert Catriona Macpherson Irene Murphy Janice Winchester Nadeau 《Death Studies》2019,43(3):173-182
Grief is a family affair, yet it is commonly viewed as an individual phenomenon. As an international, interdisciplinary team, we explore grief within a family context across theoretical, research, practice, and educational domains. Families are complex and working with this complexity is challenging but necessary for a holistic view of grief. We therefore encourage an increased focus on theorizing, researching, practicing, and educating using innovative approaches to address the complexities of grief within the context of families. Learnings from within each domain will affirm and enhance the development of family-level thinking and approaches. 相似文献
42.
Thomson HL Basmadjian AJ Rainbird AJ Razavi M Avierinos JF Pellikka PA Bailey KR Breen JF Enriquez-Sarano M 《Journal of the American College of Cardiology》2001,38(3):867-875
OBJECTIVES: We sought to assess the impact of contrast injection and harmonic imaging, on the measure by echocardiography of left ventricular (LV) remodeling. BACKGROUND: Left ventricular remodeling is a precursor of LV dysfunction, but the impact of contrast injection and harmonic imaging on the accuracy or reproducibility of echocardiography is unclear. METHODS: We prospectively collected LV images by using simultaneous methods. Then, LV volumes were measured off-line, in blinded manner and in random order. The accuracy of echocardiography was determined in comparison to electron beam computed tomography (EBCT) in 26 patients. The reproducibility of echocardiography was assessed by three blinded observers with different training levels in 32 patients. RESULTS: End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and ejection fraction (EF), as measured by EBCT (195 +/- 55, 58 +/- 24 and 137 +/- 35 ml and 71 +/- 5%, respectively) and echocardiography with harmonic imaging and contrast injection (194 +/- 51, 55 +/- 20 and 140 +/- 35 ml and 72 +/- 4%, respectively), showed no differences (all p > 0.15) and excellent correlations (all r > 0.87). In contrast, echocardiography using harmonic imaging without contrast injection underestimated the EBCT results (all p < 0.01). Reproducibility was superior with rather than without contrast injection for intraobserver and interobserver variabilities (all p < 0.001). Values measured by different observers were different without contrast injection, but were similar with contrast injection (all p > 0.18). Consequently, intrinsic patient differences represented a larger and almost exclusive proportion of global variability with contrast injection for EDV (94 vs. 79%), ESV (93 vs. 82%), SV (87 vs. 53%) and EF (84 vs. 41%), as compared with harmonic imaging without contrast injection (all p < 0.005). CONCLUSIONS: For assessment of LV remodeling, echocardiography with harmonic imaging and contrast injection improved the accuracy and reproducibility, as compared with imaging without contrast injection. With contrast injection, variability was almost exclusively due to intrinsic patient differences. Therefore, when evaluation of LV remodeling is deemed important, assessment after contrast injection should be the preferred echocardiographic approach. 相似文献
43.
P P Vitaliano A R Breen J Russo M Albert M V Vitiello P N Prinz 《Journal of chronic diseases》1984,37(9-10):743-753
Community residing patients with mild (n = 18) or moderately severe (n = 16) Alzheimer's disease and controls (n = 23) were given Mattis' Dementia Rating Scale (DRS) and a brief measure of confrontation naming selected from the Boston Naming Test (BNT). The DRS was shown to be a reliable and clinically useful measure of mental status in patients with Alzheimer's disease. The DRS subscales and the BNT had excellent internal consistency reliabilities and the total DRS score (TDRS) was shown to be generally unrelated to gender and education. Among the dementia patients, performance on the TDRS was significantly associated with functional competence. The two dementia samples had similar profiles on the DRS and BNT, with the mild subjects performing significantly better than the moderately severe subjects on each measure. Extending the range of DRS subscales would improve this measure's utility as an evaluation instrument. 相似文献
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Genetic relationships between suicide attempts,suicidal ideation and major psychiatric disorders: A genome‐wide association and polygenic scoring study
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Niamh Mullins Nader Perroud Rudolf Uher Amy W. Butler Sarah Cohen‐Woods Margarita Rivera Karim Malki Jack Euesden Robert A. Power Katherine E. Tansey Lisa Jones Ian Jones Nick Craddock Michael J. Owen Ania Korszun Michael Gill Ole Mors Martin Preisig Wolfgang Maier Marcella Rietschel John P. Rice Bertram Müller‐Myhsok Elisabeth B. Binder Susanne Lucae Marcus Ising Ian W. Craig Anne E. Farmer Peter McGuffin Gerome Breen Cathryn M. Lewis 《American journal of medical genetics. Part B, Neuropsychiatric genetics》2014,165(5):428-437
50.
Journal of Neurology - The non-motor features of Parkinson’s disease (PD) are increasingly being recognised. This review deals with the spectrum of sleep disorders associated with PD, which... 相似文献