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Delphine Tardivo Julien Sastre Jean-Hugues Catherine Georges Leonetti Pascal Adalian Bruno Foti 《International journal of legal medicine》2014,128(1):161-169
Accurate age determination is fundamental in both forensic medicine and anthropology. Many methods that relate dental characteristics to adult age have been proposed, but there is still no simple and reliable method that does not damage the study material. The aim of this work was to propose a relevant and practical technique for determining age in adults that could be used in both living and deceased individuals. The sample was composed of 210 CT scans from individuals aged from 15 to 85 years old, with four healthy canines present in the mouth. The 840 canines were modelled using Mimics® 10.01 software. The pulp volume/total volume ratio ×100 was determined for each tooth. Seven mathematical models, corresponding to all possible real situations, were determined by the weighted least squares method and ranked in order of relative performance. The adequacy of the seven models to the data was very high with the regressions proposed (0.915?<?R 2 adjusted?<?0.964). Ranked in order of performance, the maxillary model was the most powerful of the seven models for age determination, followed by the 4 canines model, the 13 model and the 23 model. 相似文献
103.
The associations between psychotic experiences and substance use and substance use disorders: findings from the World Health Organization World Mental Health surveys 下载免费PDF全文
Louisa Degenhardt Sukanta Saha Carmen C. W. Lim Sergio Aguilar‐Gaxiola Ali Al‐Hamzawi Jordi Alonso Laura H. Andrade Evelyn J. Bromet Ronny Bruffaerts José Miguel Caldas‐de‐Almeida Giovanni de Girolamo Silvia Florescu Oye Gureje Josep M. Haro Elie G. Karam Georges Karam Viviane Kovess‐Masfety Sing Lee Jean‐Pierre Lepine Victor Makanjuola Maria E. Medina‐Mora Zeina Mneimneh Fernando Navarro‐Mateu Marina Piazza José Posada‐Villa Nancy A. Sampson Kate M. Scott Juan Carlos Stagnaro Margreet Ten Have Kenneth S. Kendler Ronald C. Kessler John J. McGrath 《Addiction (Abingdon, England)》2018,113(5):924-934
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Silvio Tocco Paolo Boccolari Antonio Landi Chiara Leonelli Catia Mercanti Francesco Pogliacomi Silvana Sartini Lucia Zingarello Bernadette Nedelec 《Journal of hand therapy》2013,26(3):191-201
Study designRandomized clinical trial.IntroductionAlthough orthotic immobilization has become the preferable treatment choice for closed mallet injuries, it is unclear whether orthosis self-removal has an impact on the final outcome.PurposeTo evaluate the treatment efficacy of cast immobilization of closed mallet fingers using Quickcast® (QC) compared to a removable, lever-type thermoplastic orthosis (LTTP).Methods57 subjects were randomized in 2 groups. DIPj extensor lag and the Gaberman success scale were used as primary outcomes.ResultsLTTP subjects resulted in greater extensor lag than QC subjects (x = 5°; p = 0.05) at 12 weeks from baseline, and high edema and older age negatively affected DIPj extensor lag. No other differences were found between groups.ConclusionCast immobilization seems to be slightly more effective than the traditional approach probably for its greater capacity to reduce edema.Level of evidence1B. 相似文献
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Rita Tanios Amira Bekdash Elias Kassab Everett Stone Georges Georgiou Arthur E. Frankel Ralph J. Abi-Habib 《Leukemia research》2013
In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. Mononuclear cells and CD34+ blasts were not sensitive demonstrating the selectivity of HuArgI(Co)-PEG5000-induced arginine deprivation. Addition of l-citrulline led to the rescue of five cell lines. The four cell lines that were not rescued by l-citrulline did not express argininosuccinate synthetase-1, indicating complete arginine auxotrophy. Inhibition of autophagy increased cell sensitivity to HuArgI(Co)-PEG5000 demonstrating the protective role of autophagy following arginine deprivation. 相似文献
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Jessica L. Montoya Shereen Georges Amelia Poquette Colin A. Depp J. Hampton Atkinson 《AIDS care》2014,26(12):1477-1481
Mobile health (mHealth) interventions to promote antiretroviral therapy (ART) adherence have shown promise; however, among persons living with HIV who abuse methamphetamine (MA), effective tailoring of content to match the expressed needs of this patient population may be necessary. This study aimed (1) to understand patient perspectives of barriers and facilitators of ART adherence among people with HIV who use MA, and (2) to obtain feedback on the thematic content of an mHealth intervention in order to tailor the intervention to this subgroup. Two separate focus groups, each with 10 HIV+/MA+ individuals, were conducted. Transcribed audio recordings were qualitatively analyzed to identify emergent themes. Inter-rater reliability of themes was high (mean Kappa = .97). Adherence barriers included MA use, misguided beliefs about ART adherence, memory and planning difficulties, social barriers and perceived stigma, and mental heath issues. Facilitators of effective ART adherence were cognitive compensatory strategies, promotion of well-being, health-care supports, adherence education, and social support. Additionally, the focus groups generated content for reminder text messages to be used in the medication adherence intervention. This qualitative study demonstrates the feasibility of using focus groups to derive patient-centered intervention content to address the health challenge at hand in targeted populations. 相似文献
110.
National HIV prevalence estimates across sub-Saharan Africa range from less than 1 percent to over 25 percent. Recent research proposes several explanations for the observed variation, including prevalence of male circumcision, levels of condom use, presence of other sexually transmitted infections, and practice of multiple concurrent partnerships. However, the importance of partnership concurrency for HIV transmission may depend on how it affects coital frequency with each partner. The coital dilution hypothesis suggests that coital frequency within a partnership declines with the addition of concurrent partners. Using sexual behavior data from rural Malawi and urban Kenya, we investigate the relationship between partnership concurrency and coital frequency, and find partial support for the coital dilution hypothesis. We conclude the paper with a discussion of our findings in light of the current literature on concurrency. 相似文献