全文获取类型
收费全文 | 5001篇 |
免费 | 449篇 |
国内免费 | 40篇 |
专业分类
耳鼻咽喉 | 31篇 |
儿科学 | 115篇 |
妇产科学 | 119篇 |
基础医学 | 572篇 |
口腔科学 | 84篇 |
临床医学 | 473篇 |
内科学 | 944篇 |
皮肤病学 | 59篇 |
神经病学 | 241篇 |
特种医学 | 280篇 |
外科学 | 715篇 |
综合类 | 255篇 |
预防医学 | 467篇 |
眼科学 | 185篇 |
药学 | 368篇 |
1篇 | |
中国医学 | 96篇 |
肿瘤学 | 485篇 |
出版年
2023年 | 48篇 |
2022年 | 57篇 |
2021年 | 96篇 |
2020年 | 67篇 |
2019年 | 109篇 |
2018年 | 103篇 |
2017年 | 95篇 |
2016年 | 91篇 |
2015年 | 130篇 |
2014年 | 158篇 |
2013年 | 204篇 |
2012年 | 289篇 |
2011年 | 280篇 |
2010年 | 196篇 |
2009年 | 193篇 |
2008年 | 287篇 |
2007年 | 290篇 |
2006年 | 250篇 |
2005年 | 267篇 |
2004年 | 217篇 |
2003年 | 214篇 |
2002年 | 170篇 |
2001年 | 123篇 |
2000年 | 126篇 |
1999年 | 125篇 |
1998年 | 84篇 |
1997年 | 70篇 |
1996年 | 66篇 |
1995年 | 46篇 |
1994年 | 51篇 |
1993年 | 42篇 |
1992年 | 95篇 |
1991年 | 79篇 |
1990年 | 71篇 |
1989年 | 73篇 |
1988年 | 81篇 |
1987年 | 75篇 |
1986年 | 66篇 |
1985年 | 58篇 |
1984年 | 30篇 |
1983年 | 31篇 |
1982年 | 44篇 |
1981年 | 26篇 |
1980年 | 22篇 |
1979年 | 20篇 |
1978年 | 21篇 |
1977年 | 18篇 |
1976年 | 26篇 |
1975年 | 15篇 |
1974年 | 13篇 |
排序方式: 共有5490条查询结果,搜索用时 31 毫秒
101.
Y Fong J Evans D Brook J Kenkre P Jarvis K Gower-Thomas 《Annals of the Royal College of Surgeons of England》2015,97(2):137-139
Introduction
The Nottingham Prognostic Index (NPI) is an established prognostication tool in the management of breast cancers (BCs). Latest ten-year survival data have demonstrated an improved outlook for each NPI category and the latest UK five- and ten-year survival from BC has been reported to be 85% and 77%, respectively. We compared survival of each NPI category for BCs diagnosed within the national breast screening service in Wales (Breast Test Wales (BTW)) to the latest data, and reviewed its validity in unselected cases within a screened population.Methods
All women screened between 1998 and 2001 within BTW were included. The NPI score for each cancer was calculated using the size, nodal status, and grade of the primary tumour. Survival data (all-cause) were calculated after ten years of follow-up.Results
In the three-year screening period, 199,082 women were screened. A total of 1,712 cancers were diagnosed, and 1,546 had data available for calculating the NPI. Overall five-year and ten-year survival was 94% and 82%, respectively.Conclusions
Overall five-year and ten-year survival (all-cause) has improved even when compared with UK data for BC-specific survival. We found that the NPI remains valid for BC treatment, and that our data provide a reference for updating the all-cause survival of women diagnosed with BCs within a screened population. 相似文献102.
103.
104.
Eva Y.F. Pang Shirley S.M. Fong Mimi M.Y. Tse Eric W.C. Tam Shamay SM Ng Billy C.L. So 《Journal of Physical Therapy Science》2015,27(6):1839-1845
[Purpose] This study investigated the intra-rater, inter-rater and test-retest
reliability of the sideways step test (SST), its correlation with other indicators of
stroke-specific impairment, and the cut-off count best discriminating subjects with stroke
from their healthy counterparts. [Subjects and Methods] Forty-three subjects with chronic
stroke and 41 healthy subjects older than 50 years participated in this study. The SST was
administered along with the Fugl-Meyer motor assessment for the lower extremities
(FMA-LE), the five-times sit to stand (5TSTS) test, the Berg Balance Scale (BBS), the
movement velocity (MVL) by the limits of stability (LOS) test, the ten-metre walk (10mW)
test, the timed “Up and Go” (TUG) test and the Activities-specific Balance Confidence
(ABC) scale. [Results] The SST showed good to excellent intra-rater, inter-rater and
test-retest reliability. The SST counts correlated with 5TSTS times, 10mW times, TUG
times, and the FMA-LE and BBS scores. SST counts of 11 for the paretic leg and 14 for the
non-paretic leg were found to distinguish the healthy adults from subjects with stroke.
[Conclusion] The sideways step test is a reliable clinical test, which correlates with the
functional strength, gait speed, and functional balance of people with chronic stroke.Key words: Balance, Stroke, Rehabilitation 相似文献
105.
106.
Addya S Shiroto K Turoczi T Zhan L Kaga S Fukuda S Surrey S Duan LJ Fong GH Yamamoto F Maulik N 《Journal of molecular and cellular cardiology》2005,38(2):345-351
This study attempts to address an important clinical issue by identifying potential candidates of VEGF signaling through Flt-1 receptor that trigger angiogenic signal under ischemic stress. To determine the significance of VEGF-Flt-1 (VEGFR1) signaling in ischemic preconditioned (PC) myocardium, we used heterozygous Flt-1 knockout (KO) mice to dissect the pathway and identify candidate genes involved in VEGF signaling. DNA microarrays were employed to detect, characterize and distinguish altered myocardial gene expression by comparing between wild type (WT) CD-1 and heterozygous Flt-1 KO mice when exposed to ischemia (30 min) and reperfusion (2 h). Moreover, KO mice demonstrated reduced beneficial effects of PC when compared to the WT with PC. In the KO and WT mice, the % recovery of the left ventricular developed pressure and the maximum first derivative of the developed pressure after ischemia/reperfusion without PC were similar. However, when animals were subjected to PC, the left ventricular functional recovery throughout the reperfusion period was significantly lower in KO mice than in WT mice. These results indicate for the first time that in the heterozygous Flt-1 KO mice, PC is not as effective as that found in WT. This observation may be due to downregulation of several important genes such as growth-regulated oncogene 1 (Gro1), heat shock proteins (HSP), I kappa B kinase beta (IKK beta), colony-stimulating factor-1 (CSF-1) and annexin A7, suggesting the importance of VEGF-Flt-1 receptor signaling during PC. 相似文献
107.
108.
109.