全文获取类型
收费全文 | 1414篇 |
免费 | 85篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 34篇 |
妇产科学 | 22篇 |
基础医学 | 195篇 |
口腔科学 | 31篇 |
临床医学 | 177篇 |
内科学 | 247篇 |
皮肤病学 | 15篇 |
神经病学 | 172篇 |
特种医学 | 35篇 |
外科学 | 186篇 |
综合类 | 5篇 |
一般理论 | 1篇 |
预防医学 | 178篇 |
眼科学 | 12篇 |
药学 | 123篇 |
中国医学 | 4篇 |
肿瘤学 | 62篇 |
出版年
2023年 | 10篇 |
2022年 | 17篇 |
2021年 | 21篇 |
2020年 | 24篇 |
2019年 | 36篇 |
2018年 | 32篇 |
2017年 | 52篇 |
2016年 | 40篇 |
2015年 | 37篇 |
2014年 | 36篇 |
2013年 | 68篇 |
2012年 | 99篇 |
2011年 | 89篇 |
2010年 | 54篇 |
2009年 | 56篇 |
2008年 | 87篇 |
2007年 | 101篇 |
2006年 | 97篇 |
2005年 | 96篇 |
2004年 | 78篇 |
2003年 | 69篇 |
2002年 | 62篇 |
2001年 | 14篇 |
2000年 | 18篇 |
1999年 | 9篇 |
1998年 | 10篇 |
1997年 | 15篇 |
1996年 | 16篇 |
1995年 | 11篇 |
1994年 | 11篇 |
1993年 | 11篇 |
1992年 | 12篇 |
1991年 | 8篇 |
1990年 | 3篇 |
1989年 | 9篇 |
1988年 | 11篇 |
1987年 | 12篇 |
1986年 | 13篇 |
1985年 | 8篇 |
1984年 | 6篇 |
1983年 | 3篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 3篇 |
1978年 | 8篇 |
1974年 | 2篇 |
1970年 | 2篇 |
1969年 | 4篇 |
1967年 | 2篇 |
1966年 | 6篇 |
排序方式: 共有1501条查询结果,搜索用时 0 毫秒
31.
Children hospitalised with bronchiolitis in the first year of life have a lower quality of life nine months later
下载免费PDF全文
![点击此处可从《Acta paediatrica (Oslo, Norway : 1992)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
32.
Measuring quality of life in patients with head and neck cancer: Update of the EORTC QLQ‐H&N Module,Phase III
下载免费PDF全文
![点击此处可从《Head & neck》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Susanne Singer Cludia Araújo Juan Ignacio Arraras Ingo Baumann Andreas Boehm Bente Brokstad Herlofson Joaquim Castro Silva Wei‐Chu Chie Sheila Fisher Orlando GuntinasLichius Eva Hammerlid María Elisa Irarrzaval Marianne Jensen Hjermstad Kenneth Jensen Naomi Kiyota Lisa Licitra Ourania NicolatouGalitis Monica Pinto Marcos Santos Claudia Schmalz Allen C. Sherman Iwona M. Tomaszewska Irma Verdonck de Leeuw Noam Yarom Paola Zotti Dirk Hofmeister 《Head & neck》2015,37(9):1358-1367
33.
Romundstad LB 《Lancet》2012,379(9815):497-498
34.
35.
Rikke Guldberg Ulrik Schiøler Kesmodel Jesper Kjær Hansen Kim Oren Gradel Søren Brostrøm Linda Kærlev Bente Mertz Nørgård 《International urogynecology journal》2013,24(7):1127-1134
Introduction and hypothesis
The aim of this study was to evaluate the impact of urogynecological surgery on quality of life based on patient reported outcome measures (PROMs).Methods
Data were retrieved from the Danish Urogynaecological Database. Inclusion criteria were Danish women undergoing surgery for urinary incontinence (UI) or pelvic organ prolapse (POP) from 2006 to 2011. Using frequency of symptoms and a visual analogue scale (VAS) both pre- and postoperatively, their severity of symptoms and quality of life were measured by questionnaires.Results
During the study period, 20,629 urogynecological procedures were performed. The questionnaires on severity of symptoms and the VAS had been completed both pre- and postoperatively for approximately one third of women undergoing surgery. For UI surgery, 83 % had improved symptoms, 13 % were unchanged, and 4 % had worse symptoms postoperatively. For POP surgery, 80, 17, and 3 % were improved, unchanged, and worsened, respectively. The postoperative bother of symptoms and interference in everyday life evaluated by VAS were significantly reduced for both UI [preoperative median VAS score 9, postoperative median score 1 (p?<?0.001)] and POP [8 preoperatively and 0 postoperatively (p?<?0.001)].Conclusions
Based on PROMs, surgery for UI and POP is effective in alleviating symptoms associated with UI or POP, and it can improve quality of life in symptomatic women. Pre- and postoperative questionnaires are useful tools in assessing symptomatic outcome measures after surgery. 相似文献36.
Carpal tunnel syndrome is common during pregnancy. The symptoms usually disappear after delivery, but how soon has not been established. Thirty pregnant women with the syndrome reported to us the degree of pain in their hands every week before, and daily after, delivery. Pain was graded on a scale from 0 (none) to 10 (worst imaginable). The prevalence of the syndrome during pregnancy was about 2%. The mean pain score was 5.6 (SD 2.0) at referral and this was reduced by 1.2 (SD 2.2) after wearing an orthosis for a week. After this, it stayed almost unchanged until delivery. The score fell by half during the first week after parturition and by half again during the next week. The reduction in score was strongly correlated with loss of the weight gained during pregnancy (r?=?0.97; p<0.001). Although symptoms may persist for some weeks after delivery, the severity declines quickly. 相似文献
37.
Svend Erik Mouridsen Bente Rich Torben Isager 《Journal of autism and developmental disorders》2013,43(6):1308-1313
We performed a nationwide, register-based retrospective follow-up study of epilepsy in all people who were born between January 1, 1980 and June 29, 2006 and registered in the Danish Psychiatric Central Register with Asperger’s syndrome on February 7, 2011. All 4,180 identified cases with AS (3,431 males and 749 females) were screened through the nationwide Danish National Hospital Register (DNHR) with respect to epilepsy. Mean age at follow-up was 18.1 years (range 4–31 years). Of the 4,180 individuals with AS, 164 (3.9 %) were registered with at least one epilepsy diagnosis in the DNHR, which is significantly increased (p < 0.0001) relative to the same age group in the general population, where an estimate is about 2.0 %. 相似文献
38.
Baelum V Hintze H Wenzel A Danielsen B Nyvad B 《Community dentistry and oral epidemiology》2012,40(3):257-266
Baelum V, Hintze H, Wenzel A, Danielsen B, Nyvad B. Implications of caries diagnostic strategies for clinical management decisions. Community Dent Oral Epidemiol 2011. © 2011 John Wiley & Sons A/S Abstract – Objectives: In clinical practice, a visual–tactile caries examination is frequently supplemented by bitewing radiography. This study evaluated strategies for combining visual–tactile and radiographic caries detection methods and determined their implications for clinical management decisions in a low‐caries population. Methods: Each of four examiners independently examined preselected contacting interproximal surfaces in 53 dental students aged 20–37 years using a visual–tactile examination and bitewing radiography. The visual–tactile examination distinguished between noncavitated and cavitated lesions while the radiographic examination determined lesion depth. Direct inspection of the surfaces following tooth separation for the presence of cavitated or noncavitated lesions was the validation method. The true‐positive rate (i.e. the sensitivity) and the false‐positive rate (i.e. 1‐specificity) were calculated for each diagnostic strategy. Results: Visual–tactile examination provided a true‐positive rate of 34.2% and a false‐positive rate of 1.5% for the detection of a cavity. The combination of a visual–tactile and a radiographic examination using the lesion in dentin threshold for assuming cavitation had a true‐positive rate of 76.3% and a false‐positive rate of 8.2%. When diagnostic observations were translated into clinical management decisions using the rule that a noncavitated lesion should be treated nonoperatively and a cavitated lesion operatively, our results showed that the visual–tactile method alone was the superior strategy, resulting in most correct clinical management decisions and most correct decisions regarding the choice of treatment. 相似文献
39.
Chan Yong Schüle Bente Thamsen Bastian Blümel Michael Lommel Tamer Karakaya Christian Oliver Paschereit Klaus Affeld Ulrich Kertzscher 《Artificial organs》2016,40(11):E192-E202
Left ventricular assist devices (LVADs) have become a standard therapy for patients with severe heart failure. As low blood trauma in LVADs is important for a good clinical outcome, the assessment of the fluid loads inside the pump is critical. More specifically, the flow features on the surfaces where the interaction between blood and artificial material happens is of great importance. Therefore, experimental data for the near‐wall flows in an axial rotary blood pump were collected and directly compared to computational fluid dynamic results. For this, the flow fields based on unsteady Reynolds‐averaged Navier–Stokes simulations‐computational fluid dynamics (URANS‐CFD) of an axial rotary blood pump were calculated and compared with experimental flow data at one typical state of operation in an enlarged model of the pump. The focus was set on the assessment of wall shear stresses (WSS) at the housing wall and rotor gap region by means of the wall‐particle image velocimetry technique, and the visualization of near‐wall flow structures on the inner pump surfaces by a paint erosion method. Additionally, maximum WSS and tip leakage volume flows were measured for 13 different states of operation. Good agreement between CFD and experimental data was found, which includes the location, magnitude, and direction of the maximum and minimum WSS and the presence of recirculation zones on the pump stators. The maximum WSS increased linearly with pressure head. They occurred at the upstream third of the impeller blades and exceeded the critical values with respect to hemolysis. Regions of very high shear stresses and recirculation zones could be identified and were in good agreement with simulations. URANS‐CFD, which is often used for pump performance and blood damage prediction, seems to be, therefore, a valid tool for the assessment of flow fields in axial rotary blood pumps. The magnitude of maximum WSS could be confirmed and were in the order of several hundred Pascal. 相似文献
40.
Mortality and Causes of Death in Patients With Osteogenesis Imperfecta: A Register‐Based Nationwide Cohort Study
下载免费PDF全文
![点击此处可从《Journal of bone and mineral research》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Lars Folkestad Jannie Dahl Hald Vladimir Canudas‐Romo Jeppe Gram Anne Pernille Hermann Bente Langdahl Bo Abrahamsen Kim Brixen 《Journal of bone and mineral research》2016,31(12):2159-2166
Osteogenesis imperfecta (OI) is a hereditary connective tissue disease that causes frequent fractures. Little is known about causes of death and length of survival in OI. The objective of this work was to calculate the risk and cause of death, and the median survival time in patients with OI. This study was a Danish nationwide, population‐based and register‐based cohort study. We used National Patient Register data from 1977 until 2013 with complete long‐term follow‐up. Participants comprised all patients registered with the diagnosis of OI from 1977 until 2013, and a reference population matched five to one to the OI cohort. We calculated hazard ratios for all‐cause mortality and subhazard ratios for cause‐specific mortality in a comparison of the OI cohort and the reference population. We also calculated all‐cause mortality hazard ratios for males, females, and age groups (0 to 17.99 years, 18.00 to 34.99 years, 35.00 to 54.99 years, 55.00 to 74.99 years, and >75 years). We identified 687 cases of OI (379 women) and included 3435 reference persons (1895 women). A total of 112 patients with OI and 257 persons in the reference population died during the observation period. The all‐cause mortality hazard ratio between the OI cohort and the reference population was 2.90. The median survival time for males with OI was 72.4 years, compared to 81.9 in the reference population. The median survival time for females with OI was 77.4 years, compared to 84.5 years in the reference population. Patients with OI had a higher risk of death from respiratory diseases, gastrointestinal diseases, and trauma. We were limited by the lack of clinical information about phenotype and genotype of the included patients. Patients with OI had a higher mortality rate throughout their life compared to the general population. © 2016 American Society for Bone and Mineral Research. 相似文献