全文获取类型
收费全文 | 11412篇 |
免费 | 674篇 |
国内免费 | 104篇 |
专业分类
耳鼻咽喉 | 106篇 |
儿科学 | 227篇 |
妇产科学 | 309篇 |
基础医学 | 1433篇 |
口腔科学 | 446篇 |
临床医学 | 1015篇 |
内科学 | 2831篇 |
皮肤病学 | 135篇 |
神经病学 | 968篇 |
特种医学 | 476篇 |
外科学 | 1883篇 |
综合类 | 34篇 |
预防医学 | 489篇 |
眼科学 | 119篇 |
药学 | 674篇 |
中国医学 | 31篇 |
肿瘤学 | 1014篇 |
出版年
2024年 | 9篇 |
2023年 | 89篇 |
2022年 | 228篇 |
2021年 | 391篇 |
2020年 | 230篇 |
2019年 | 335篇 |
2018年 | 408篇 |
2017年 | 282篇 |
2016年 | 341篇 |
2015年 | 396篇 |
2014年 | 602篇 |
2013年 | 655篇 |
2012年 | 960篇 |
2011年 | 969篇 |
2010年 | 522篇 |
2009年 | 507篇 |
2008年 | 763篇 |
2007年 | 783篇 |
2006年 | 645篇 |
2005年 | 644篇 |
2004年 | 640篇 |
2003年 | 511篇 |
2002年 | 410篇 |
2001年 | 67篇 |
2000年 | 52篇 |
1999年 | 75篇 |
1998年 | 75篇 |
1997年 | 72篇 |
1996年 | 58篇 |
1995年 | 56篇 |
1994年 | 58篇 |
1993年 | 53篇 |
1992年 | 33篇 |
1991年 | 39篇 |
1990年 | 32篇 |
1989年 | 28篇 |
1988年 | 27篇 |
1987年 | 19篇 |
1986年 | 19篇 |
1985年 | 11篇 |
1984年 | 14篇 |
1983年 | 9篇 |
1982年 | 10篇 |
1981年 | 8篇 |
1980年 | 5篇 |
1979年 | 6篇 |
1977年 | 5篇 |
1975年 | 6篇 |
1974年 | 6篇 |
1973年 | 7篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
111.
Valeria Romeo Arnaldo Stanzione Divina DAuria Ludovica Fulgione Fabio Giusto Simone Maurea Arturo Brunetti 《Journal of Ultrasound》2022,25(4):965
Aimslymphadenopathy can occur after COVID-19 vaccination and when encountered at ultrasound examinations performed for other reasons might pose a diagnostic challenge. Purpose of the study was to evaluate the incidence, course and ultrasound imaging features of vaccine-induced lymphadenopathy.Methods89 healthy volunteers (median age 30, 76 females) were prospectively enrolled. Vaccine-related clinical side effects (e.g., fever, fatigue, palpable or painful lymphadenopathy) were recorded. Participants underwent bilateral axillary, supraclavicular and cervical lymph node stations ultrasound 1–4 weeks after the second dose and then again after 4–12 weeks in those who showed lymphadenopathy at the first ultrasound. B-mode, color-Doppler assessment, and shear-wave elastography (SWE) evaluation were performed. The correlation between lymphadenopathy and vaccine-related side effects was assessed using the Fisher’s exact test.ResultsPost-vaccine lymphadenopathy were found in 69/89 (78%) participants (37 single and 32 multiple lymphadenopathy). Among them, 60 presented vaccine-related side effects, but no statistically significant difference was observed between post-vaccine side effect and lymphadenopathy. Ultrasound features of vaccine-related lymphadenopathy consisted of absence of fatty hilum, round shape and diffuse or asymmetric cortical thickness (median cortical thickness of 5 mm). Vascular signal was mainly found to be increased, localized in both central and peripheral regions. SWE showed a soft cortical consistence in all cases (median value 11 Kpa). At follow-up, lymph-node morphology was completely restored in most cases (54/69, 78%) and in no case lymphadenopathy had worsened.ConclusionA high incidence of vaccine-induced lymphadenopathy was found in a population of healthy subjects, with nearly complete regression within 4–12 weeks.Supplementary InformationThe online version contains supplementary material available at 10.1007/s40477-022-00674-3. 相似文献
112.
Filippo Catalano Antonello Trecca Luca Rodella Francesco Lombardo Anna Tomezzoli Serena Battista Marco Silano Fabio Gaj Giovanni de Manzoni 《Surgical endoscopy》2009,23(7):1581-1586
Background Endoscopic submucosal dissection (ESD) has been developed as treatment for early gastric cancer (EGC) by Japanese authors.
However, there are no reports about its possible implementation in the Western setting. The aim of the present work is to
determine the safety and efficacy of the endoscopic treatments for EGC in an Italian cohort.
Methods Forty-five patients for a total of 48 gastric lesions were enrolled in the study. Thirty-six EMR procedures were performed
with the strip biopsy technique using a double-channel endoscope. En bloc resection refers to resection in one piece, while
piecemeal refers to resections in which the lesion was removed in multiple fragments. A total of 12 ESD were performed and
completed with IT knife. We define as curative treatment lateral and vertical margins of the resected specimens free of cancer
and repeat endoscopic finding of no recurrent disease.
Results Out of 36 EMR procedures, 10 were piecemeal resections (28%), while 26 were en bloc (72%). ESD led to en bloc resection in
11/12 cases (92%). Histological assessment of curability in the EMR group was achieved in 56% of the cases, and in 92% of
the ESD group. Mean follow-up period was 31 months (range: 12–71 months). There was no local recurrence or distant metastasis
in the curative group patients.
Conclusions These results seem to confirm the safety and the clinical efficacy of the ESD procedure in the Western world too. 相似文献
113.
The hospital records of 639 patients affected by primary gastric cancer who were consecutively admitted to our unit during
the period 1981–1995 were reviewed. Overall 220 underwent total gastrectomy (38 palliative), 12 had resection of the gastric
stump, 195 had distal subtotal gastrectomy (55 palliative), 78 had bypass procedures, 72 had explorative laparotomy, and 62
had no operation. Univariate and multivariate analyses were used to evaluate 5-year survival with respect to the main clinical,
pathologic, and treatment variables after both curative and palliative treatments. Overall the 5-year survival after curative
treatment (320 patients—operative mortality excluded) was 55.5%: 91.1% for stage IA, 71.5% IB, 62.4% II, 37.5% IIIA, 31.5%
IIIB. Among patients who underwent palliative treatment 5-year survival was 13.1% after gastric resection (total or distal
subtotal), 4.9% after the bypass procedures, 0 after explorative laparotomy, and 0 after no operation. Univariate and multivariate
survival analyses showed that variables independently associated with poor survival were advanced stage, upper location and
D1 lymphadenectomy after curative treatment, tumor spread to distant sites, and nonresectional surgery after palliative treatment.
Multivariate analysis showed that even though survival with gastric cancer depends on predetermined factors, the type of surgery
can have a significant effect on prognosis after both curative and palliative treatment. 相似文献
114.
Fabio Vescini 《Clinical reviews in bone and mineral metabolism》2012,10(4):235-235
115.
116.
117.
Rodrigo Vitório Ellen Lirani-Silva Fabio Augusto Barbieri Vivian Raile Florindo Stella Lilian Teresa Bucken Gobbi 《Gait & posture》2013,37(2):330-334
The purpose of the current study was to investigate the role of visual information on gait control in people with Parkinson's disease as they crossed over obstacles. Twelve healthy individuals, and 12 patients with mild to moderate Parkinson's disease, walked at their preferred speeds along a walkway and stepped over obstacles of varying heights (ankle height or half-knee height), under three visual sampling conditions: dynamic (normal lighting), static (static visual samples, similar to stroboscopic lighting), and voluntary visual sampling. Subjects wore liquid crystal glasses for visual manipulation. In the static visual sampling condition only, the patients with Parkinson's disease made contact with the obstacle more often than did the control subjects. In the successful trials, the patients increased their crossing step width in the static visual sampling condition as compared to the dynamic and voluntary visual sampling conditions; the control group maintained the same step width for all visual sampling conditions. The patients showed lower horizontal mean velocity values during obstacle crossing than did the controls. The patients with Parkinson's disease were more dependent on optic flow information for successful task and postural stability than were the control subjects. Bradykinesia influenced obstacle crossing in the patients with Parkinson's disease. 相似文献
118.
119.
120.
Matthew D. Neal Jay S. Raval Darrell J. Triulzi Richard L. Simmons 《Transfusion medicine reviews》2013,27(2):113-118
The transfusion of red blood cells (RBCs), although necessary for treatment of anemia and blood loss, has also been linked to increased morbidity and mortality. RBCs stored for longer durations and transfused in larger volumes are often cited as contributory to adverse outcomes. The potential mechanisms underlying deleterious effects of RBC transfusion are just beginning to be elucidated. In this narrative review, we explore the hypothesis that prolonged RBC storage results in elaboration of substances which may function as danger associated molecular pattern molecules that activate the innate immune system with consequences unfavorable to healthy homeostasis. The nature of these chemical mediators and the biological responses to them offers insight into the mechanisms of these pathological responses. Three major areas of activation of the innate immune apparatus by stored RBCs have been tentatively identified: RBC hemolysis, recipient neutrophil priming, and reactive oxygen species production. The possible mechanisms by which each might perturb the innate immune response are reviewed in a search for potential novel pathways through which transfusion can lead to an altered inflammatory response. 相似文献