全文获取类型
收费全文 | 172471篇 |
免费 | 8949篇 |
国内免费 | 209篇 |
专业分类
耳鼻咽喉 | 2658篇 |
儿科学 | 5977篇 |
妇产科学 | 4215篇 |
基础医学 | 26001篇 |
口腔科学 | 5836篇 |
临床医学 | 14629篇 |
内科学 | 31275篇 |
皮肤病学 | 4572篇 |
神经病学 | 17698篇 |
特种医学 | 6888篇 |
外科学 | 25093篇 |
综合类 | 783篇 |
一般理论 | 65篇 |
预防医学 | 10676篇 |
眼科学 | 3541篇 |
药学 | 11516篇 |
中国医学 | 261篇 |
肿瘤学 | 9945篇 |
出版年
2023年 | 1011篇 |
2022年 | 977篇 |
2021年 | 2067篇 |
2020年 | 1721篇 |
2019年 | 2251篇 |
2018年 | 3746篇 |
2017年 | 3134篇 |
2016年 | 3972篇 |
2015年 | 3652篇 |
2014年 | 4169篇 |
2013年 | 6916篇 |
2012年 | 8889篇 |
2011年 | 9762篇 |
2010年 | 5669篇 |
2009年 | 4299篇 |
2008年 | 9591篇 |
2007年 | 9964篇 |
2006年 | 9624篇 |
2005年 | 9569篇 |
2004年 | 8854篇 |
2003年 | 8935篇 |
2002年 | 8620篇 |
2001年 | 5804篇 |
2000年 | 7011篇 |
1999年 | 4305篇 |
1998年 | 1896篇 |
1997年 | 1578篇 |
1996年 | 1261篇 |
1995年 | 1109篇 |
1994年 | 1051篇 |
1993年 | 968篇 |
1992年 | 1424篇 |
1991年 | 1290篇 |
1990年 | 1304篇 |
1989年 | 1310篇 |
1988年 | 1143篇 |
1987年 | 1232篇 |
1986年 | 1064篇 |
1985年 | 1195篇 |
1984年 | 1081篇 |
1983年 | 904篇 |
1982年 | 822篇 |
1981年 | 772篇 |
1980年 | 689篇 |
1979年 | 821篇 |
1978年 | 688篇 |
1977年 | 662篇 |
1976年 | 594篇 |
1975年 | 628篇 |
1974年 | 633篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
81.
Maximum anchorage often presents a problem that is difficult to solve during orthodontic tooth movement. Stationary, skeletal anchorage can be achieved in a simple, minimally-invasive manner, and unwanted tooth movements in opposite directions can be prevented by using transmucosally-inserted bone screws.Our initial experience using the FAMI screw as an orthodontic micro-implant proved to be clinically and histologically successful. 相似文献
82.
M. Knappik U. Börner T. Jelinek 《European journal of clinical microbiology & infectious diseases》2005,24(10):701-703
The study presented here was conducted to evaluate the performance of the newly available RIDASCREEN Set (R-Biopharm AG, Darmstadt,
Germany) for the detection of immunoglobulin G antibodies against Entamoeba histolytica. The sensitivity and specificity of this new enzyme-linked immunosorbent assay were evaluated using a panel of sera from
239 individuals. The assay was positive for 43 of 44 patients with invasive amebiasis, including all 18 patients with amebic
liver abscess, while it was negative for 190 of 195 adult controls who were either healthy individuals or patients with other
parasitic diseases. The kit was found to be highly specific (97.4%) and sensitive (97.7%) for detecting antibodies against
E. histolytica in humans. Although antibody titers in patients with amebic liver abscess tend to be higher on average than in patients with
invasive amebiasis, it is not possible to distinguish the two forms solely based on the results of this commercial test. 相似文献
83.
B Dahlstr?m 《International anesthesiology clinics》1986,24(2):29-42
Spinal opiate analgesia has opened an exciting new field of research and has also rapidly gained widespread clinical acceptance. This mode of administration has obvious and definite advantages over conventional pain therapy; however, the field is still at an early stage of development. More research is clearly needed to provide methods for coping with some of the drawbacks of this method of pain relief. Important areas for future research include (1) the CSF kinetics of opiates; (2) the physiological mechanisms underlying the rostral spread of drugs within the CSF compartment; (3) a search for safer and more selective drugs; and (4) an evaluation of the extent to which pain-modulating systems at different levels in the CNS can be regulated by opiates and drugs interfering with other neurotransmitters. In this context it is essential to emphasize the importance of simultaneous study of the pharmacokinetics and the pharmacodynamic/clinical effects in providing a rational basis for a better understanding of the mechanisms of actions underlying spinal opiate analgesia. 相似文献
84.
Priv.-Doz. Dr. Rüdiger Dissmann Joachim Schröder MD PhD Prof. Dr. med. Heinz Völler Prof. Dr. med. Steffen Behrens 《Clinical research in cardiology》2006,95(4):241-243
Summary During pacemaker implantation in a patient with permanent atrial fibrillation, it remained impossible to advance a passive
fixation lead with fins through the right atrium. However, a lead with a retractable screw easily passed the right atrium
and was positioned in the right ventricle. Transesophageal echocardiography revealed an extensive net–like perforated Eustachian
valve within the right atrium that had caused entrapment of the anchor fins during lead implantation. Remnants of embryonal
structures within the right atrium should be considered a rare possible barrier during pacemaker implantation. 相似文献
85.
86.
87.
Ophira Salomon Joseph Moisseiev Tamara Vilganski Rima Dardik Shimon Kurtz Eva Shpringer David M Steinberg Nurit Rosenberg 《Blood coagulation & fibrinolysis》2006,17(6):485-488
To determine whether polymorphisms of platelet surface glycoprotein associated with arterial thrombosis are risk factors for branch retinal vein occlusion. A case-control study in which 69 patients with branch retinal vein occlusion and 147 controls who attended the eye clinic for nonvascular complications participated. DNA was extracted from whole blood and analyzed for genotyping of platelet glycoprotein polymorphisms by polymerase chain reactions and specific restricted enzymes. No relationship was found between the four platelet glycoprotein polymorphisms i.e. GPIa C807T, VNTR and Kozak of glycoprotein Ibalpha, the HPA-1 of glycoprotein IIIa and the occurrence of branch retinal vein occlusion. The HPA-2 polymorphism was found in 18 out 60 (30%) patients with branch retinal vein occlusion in comparison with 27 out 142 (19%) of controls, with an estimated odds ratio of 1.8 (95% confidence interval, 0.91-3.65). The four platelet glycoprotein polymorphisms are not risk factors for branch retinal vein occlusion and therefore it seems unnecessary to screen those patients for it. A larger study is required, however, to determine whether HPA-2 is a novel risk factor for branch retinal vein occlusion. 相似文献
88.
Gastric cancer still represents the second most common cause of gastrointestinal cancers in Germany. A disturbing issue is that at the time of diagnosis there are less than 15% of patients for whom a cure can be achieved. Nowadays, biological, histomorphological, molecular genetic and epidemiological data suggest that Helicobacter pylori eradication may lead to the prevention of gastric pre-neoplastic lesions and even gastric cancer. At present, eradication can be offered to selected patients and populations at increased risk, but more research is required before embarking on general and global H. pylori eradication for gastric cancer prevention. The main challenge is to determine how long mucosal abnormalities remain reversible and gastric cancer development can be halted. 相似文献
89.
Birgitta Malmberg Göran Kecklund Björn Karlson Roger Persson Per Flisberg Palle Ørbaek 《BMC health services research》2010,10(1):239
Background
It is well known that physicians' night-call duty may cause impaired performance and adverse effects on subjective health, but there is limited knowledge about effects on sleep duration and recovery time. In recent years occupational stress and impaired well-being among anaesthesiologists have been frequently reported for in the scientific literature. Given their main focus on handling patients with life-threatening conditions, when on call, one might expect sleep and recovery to be negatively affected by work, especially in this specialist group. The aim of the present study was to examine whether a 16-hour night-call schedule allowed for sufficient recovery in anaesthesiologists compared with other physician specialists handling less life-threatening conditions, when on call. 相似文献90.
Levente Gáspár Zoltán Jónás László Kiss György Vereb Zoltán Csernátony 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2009,19(6):403-407
Background Coccygodynia can cause severe pain and disability in patients. There are contradictions in the literature regarding the final
results of coccygectomy for coccygodynia. We evaluated the long-term effects of coccygectomy on the intensity, characteristics,
and manifestation of pain caused by coccygodynia to determine the adequacy of operation among treatment modalities.
Materials and methods Thirty-four patients with coccygodynia were treated by coccygectomy. In 22 cases, trauma, and in one case childbirth was the
cause. 11 cases were regarded as idiopathic. The intensity, characteristics of pain, and the most painful activities were
evaluated at an average of 7.6 (3–18) years of follow-up time.
Results Before the operation, all 34 patients had pain while sitting, moreover, 26 of them had pain during standing, walking, at night
or a combination of these. 21 patients had intolerable or very intensive, mainly acute, sharp or burning pain. 11 patients
had dyschesia, 2 had dysuria and 6 had dyspareunia. At follow-up, 7 patients were completely free of pain, 15 others had moderate,
11 medium, and only one patient had severe, but none had intolerable pain. Only seven patients had acute, sharp or burning
pain postoperatively. The decrease of average pain score from 8.0 to 3.2 was significant (P < 10−12). The number of the patients with dyschesia and dyspareunia decreased from 11 to 7 and from 6 to 3, respectively. Two patients
had dysuria, but their complaints did not change after the operation. One of the two patients who needed reoperation had an
excellent final result, while the other remained unchanged. 12 and 16 patients (together 82%) regarded the final result of
the operation excellent and good, respectively. The condition of five others did not change, while one became worse. The patients
with younger age, smaller body mass index, and less co-morbidities had better final result. There were no serious complications.
Conclusion Coccygectomy for coccygodynia is a safe method to decrease the intensity of pain and other complaints of the patients. The
operation can be the choice of treatment if conservative measures fail. 相似文献