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排序方式: 共有276条查询结果,搜索用时 14 毫秒
51.
52.
Correlation Between Pesticide Use in Agriculture and Adverse Birth Outcomes in Brazil: An Ecological Study 总被引:1,自引:0,他引:1
Marília Teixeira de Siqueira Cynthia Braga José Eulálio Cabral-Filho Lia Giraldo da Silva Augusto José Natal Figueiroa Ariani Impieri Souza 《Bulletin of environmental contamination and toxicology》2010,84(6):647-651
This ecological study analyzed the association between pesticide use and prematurity, low weight and congenital abnormality
at birth, infant death by congenital abnormality, and fetal death in Brazil in 2001. Simple linear regression analysis has
determined a positive association between pesticide use and prematurity, low birth weight, and congenital abnormality. The
association between pesticide use and low birth weight (p = 0.045) and, congenital abnormality (p = 0.004) and infant death rate by congenital abnormality (p = 0.039) remained after the adjustment made by the proportion of pregnant women with a low number of prenatal care visits. 相似文献
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Mara A. Guzmán-Ruiz Natalí N. Guerrero-Vargas Alejandra Lagunes-Cruz Shellye González-González Jesús Enrique García-Aviles Gabriela Hurtado-Alvarado Rebeca Mendez-Hernández Anahí Chavarría-Krauser Jean-Pascal Morin Virginia Arriaga-Avila Ruud M. Buijs Rosalinda Guevara-Guzmán 《Glia》2023,71(2):155-167
Microglia is considered the central nervous system (CNS) resident macrophages that establish an innate immune response against pathogens and toxins. However, the recent studies have shown that microglial gene and protein expression follows a circadian pattern; several immune activation markers and clock genes are expressed rhythmically without the need for an immune stimulus. Furthermore, microglia responds to an immune challenge with different magnitudes depending on the time of the day. This review examines the circadian control of microglia function and the possible physiological implications. For example, we discuss that synaptic prune is performed in the cortex at a certain moment of the day. We also consider the implications of daily microglial function for maintaining biological rhythms like general activity, body temperature, and food intake. We conclude that the developmental stage, brain region, and pathological state are not the only factors to consider for the evaluation of microglial functions; instead, emerging evidence indicates that circadian time as an essential aspect for a better understanding of the role of microglia in CNS physiology. 相似文献
55.
Reverberi C Bonatti LL Frackowiak RS Paulesu E Cherubini P Macaluso E 《NeuroImage》2012,59(2):1752-1764
Deduction is the ability to draw necessary conclusions from previous knowledge. Here we propose a novel approach to understanding the neural basis of deduction, which exploits fine-grained inter-participant variability in such tasks. Participants solved deductive problems and were grouped by the behavioral strategies employed, i.e., whether they were sensitive to the logical form of syllogistic premises, whether the problems were solved correctly, and whether heuristic strategies were employed. Differential profiles of neural activity can predict membership of the first two of these groups. The predictive power of activity profiles is distributed non-uniformly across the brain areas activated by deduction. Activation in left ventro-lateral frontal (BA47) and lateral occipital (BA19) cortices predicts whether logically valid solutions are sought. Activation of left inferior lateral frontal (BA44/45) and superior medial frontal (BA6/8) cortices predicts sensitivity to the logical structure of problems. No specific pattern of activation was associated with the use of a non-logical heuristic strategy. Not only do these findings corroborate the hypothesis that left BA47, BA44/45 and BA6/8 are critical for making syllogistic deductions, but they also imply that they have different functional roles as components of a dedicated network. We propose that BA44/45 and BA6/8 are involved in the extraction and representation of the formal structure of a problem, while BA47 is involved in the selection and application of relevant inferential rules. Finally, our findings suggest that deductive reasoning can be best described as a cascade of cognitive processes requiring the concerted operation of several, functionally distinct, brain areas. 相似文献
56.
Agnaldo Lopes da Silva-Filho Pedro A. L. S. Martins Marco P. Parente Cristina S. Saleme Thuane Roza Marcos Pinotti Teresa Mascarenhas Renato M. Natal Jorge 《Archives of gynecology and obstetrics》2010,282(2):149-155
Introduction
Pelvic floor (PF) dysfunctions represent a frequent and complex problem for women. The interaction between the vagina and its supportive structures, that are designed to support increases in abdominal pressure, can be considered a biomechanical system. Recent advances in imaging technology have improved the assessment of PF structures. The aim of this paper is to review the applications of biomechanics in urogynecology. 相似文献57.
Martina Gandola Alessio Toraldo Paola Invernizzi Laura Corrado Maurizio Sberna Ignazio Santilli Gabriella Bottini Eraldo Paulesu 《Neuropsychologia》2013
Neglect patients' performance during cancellation tasks is characterized by left sided omissions and, in many cases, by the production of inappropriate material of various kinds in the ipsilesional space, e.g. additional marks over already cancelled targets, marks drawn away from targets, scribbles, irrelevant drawings. It is unclear whether these behaviours, which have collectively been called perseverative, are functionally and anatomically connected and whether they correlate with the severity of neglect. Here we report a retrospective study on 33 right brain damaged patients with neglect after right hemisphere lesions in whom we measured the intensity of perseveration of the three following kinds: (1) ‘additional marks' (AM) perseveration where patients cancelled a target with two or more well separated marks; (2) ‘scribble’ perseveration, where patients, instead of cancelling the target with a single pen stroke as required by the task, performed multiple pen strokes without breaking the pen-to-paper contact, with the final product being a scribble; (3) ‘flying marks’ (FM) perseveration where patients produced cancellation marks well away from the targets. We found that AM and FM perseveration correlated with neglect severity, while ‘scribble’ perseveration did not. The lesion-symptom mapping showed three separate anatomical areas in the right hemisphere: ‘scribble’ perseveration was associated with lesions of the orbitofrontal cortex and caudate nucleus; AM perseveration was associated with damage to the rolandic operculum, superior temporal gyrus and inferior frontal gyrus; FM perseveration was associated with damage to the dorsal premotor cortex and the temporal pole. Neglect severity followed damage to a region which grossly corresponds to the sum of the regions associated with AM and FM perseveration respectively. This complex behavioural and anatomical pattern is interpreted in terms of a three-factor model, in which AM perseveration is caused by a deficit of disengagement of attention from the right side (also causing omissions), FM perseveration is caused by directional hypokinesia (also causing left-side omissions), and ‘scribble’ perseveration is the consequence of a failure to inhibit an initiated motor act, which is completely separate (both anatomically and functionally) from the disorder inducing omissions. 相似文献
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59.
José Araújo Holanda-Filho Ariani Impieri Souza Alex Sandro Rolland Souza José Natal Figueroa Ana Laura Carneiro G. Ferreira José Eulálio Cabral-Filho 《Archives of gynecology and obstetrics》2011,284(2):299-302
Purpose
The aim of this study was to determine the correlation between fetal transverse cerebellar diameter (TCD) and gestational age of male and female fetus in women under low-risk prenatal care between the 13th and 40th week of gestation. 相似文献60.
A de C Gomes M D Bitencourt D Natal P L Pinto L F Mucci M B de Paula P R Urbinatti J M Barata 《Revista de saúde pública》1999,33(1):95-97
Larvae and adult forms of Aedes albopictus were found during ecological study of anopheline mosquitos in the rural zone of the state of Mato Grosso do Sul in Brazil. This occurrence was registered, for the first time in Brazil, in an enzoootic area if sylvatic yellow fever virus. This implies a potential risk of the transfer of this virus to an urban area infested with Aedes aegypti. 相似文献