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61.
Antonio Prunas Emanuele Preti Julia Huemer Richard J. Shaw Hans Steiner 《Comprehensive psychiatry》2014
Objectives
The aim of the present study is to explore the association between defensive functioning (as assessed through the REM-71) and psychiatric symptoms in a large sample from the community, and the moderating role of age and gender on that association. Furthermore, we explored the concurrent validity of REM-71 as compared with “caseness” (SCL-90-R).Methods
The REM-71 was administered together with SCL-90-R to a community sample of 1,060 Italian high-school and university students (mean age = 19.01 ± 3.85 years; 66.7% females).Results
Factor 1 defenses were by far the primary contributors to the predictor synthetic variable (i.e. association between defenses and psychopathology). Gender proved to moderate the association between immature defenses and symptoms. Using ROC analysis, we derived a cut-off score for Factor 1 defenses.Conclusions
Our results support the adoption of the REM-71 as a useful instrument for the assessment of defensive array and psychopathological liability in adolescents and adults. 相似文献62.
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Tarnoki AD Tarnoki DL Stazi MA Medda E Cotichini R Nisticò L Fagnani C Lucatelli P Boatta E Zini C Fanelli F Baracchini C Meneghetti G Osztovits J Jermendy G Préda I Kiss RG Metneki J Horvath T Karlinger K Racz A Lannert A Molnar AA Littvay L Garami Z Berczi V Schillaci G 《Journal of hypertension》2012,30(8):1564-1571
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Emanuele Cereda Michela Barichella Erica Cassani Riccardo Caccialanza Gianni Pezzoli 《Parkinsonism & related disorders》2013,19(12):1094-1099
BackgroundLiterature suggests that sex steroid hormones may modify the risk for Parkinson's disease (PD). We investigated the potential effect of reproductive factors on the clinical features of idiopathic PD (IPD) patients.MethodsAll IPD female patients admitted to and evaluated at our Institute over a 12-month period were included in the present cross-sectional study. We investigated the effect of the following parameters by multivariate linear regression analysis: age at menarche, age at menopause, length of fertile life, duration of exposure to endogenous estrogens and cumulative length of pregnancies, use of contraceptives and hormonal replacement therapy.ResultsIn total, 579 patients were evaluated and 497 reported menopause before PD onset. In this population, age at PD onset was positively associated with age at menarche and at menopause, length of fertile life and duration of estrogen exposure. Moreover, UPDRS motor score was inversely associated with age at menopause, length of fertile life and duration of estrogen exposure. Increasing age at menarche was also associated with predominant resting tremor at PD onset. In models refitted on patients with early PD (disease duration <5 years; N = 226) all the associations found were confirmed. The relationship between surrogates of estrogen exposure and UPDRS motor score actually became more significant.ConclusionsOur observations support the concept that hormonal exposure of the nigro-striatal network during life may influence its susceptibility to degenerative stimuli in later life, but the association does not seem to be unique? unidirectional. In particular, increased severity of PD signs correlates with shorter duration of estrogen exposure. The underlying mechanisms need to be clarified. 相似文献
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Mario Bonomini Lorenzo Di Liberato Goffredo Del Rosso Antonio Stingone Giancarlo Marinangeli Agostino Consoli Silvio Bertoli Amedeo De Vecchi Emanuele Bosi Roberto Russo Roberto Corciulo Loreto Gesualdo Francesco Giorgino Paolo Cerasoli Augusto Di Castelnuovo Maria Pia Monaco Ty Shockley Claudia Rossi Arduino Arduini 《American journal of kidney diseases》2013