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101.
GL Moore ; DH Marks ; RA Carmen ; ME Ledford ; EJ Nelson ; RJ Fishman ; BS Leng 《Transfusion》1988,28(3):221-225
A red cell additive solution (AS-005) containing ascorbate-2-phosphate (AsP) to maintain 2,3-diphosphoglycerate, plus adenine, phosphate, and mannitol to retain viability and reduce hemolysis, was evaluated by human clinical trials. A crossover design was used with another additive solution (Nutricel AS-3, Cutter Laboratories) serving as the control for each donor. Each additive solution was evaluated at 35 and 42 days of storage. There was no significant difference between the red cell viability of the two storage solutions at either time period. Split-bag, AS-005 in vitro studies at two temperatures (2.5 and 5.5 degrees C), both within the range of 1 to 6 degrees C approved by the American Association of Blood Banks and the Food and Drug Administration, resulted in dramatically different in vitro parameters, including a threefold difference in 2,3-diphosphoglycerate (2,3-DPG), a fivefold difference in glucose, and significant differences in pH and adenosine triphosphate. High-pressure liquid chromatography data confirmed the preliminary report that 1 to 2 percent (wt/wt) oxalate was present in preparations of AsP. In vitro storage data confirmed that oxalate is the active component of AsP that preserves 2,3-DPG during storage. 相似文献
102.
103.
Punch biopsies are frequently used in the diagnosis of oral disease and are associated with few complications. We report a case of surgical emphysema following this procedure. 相似文献
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106.
0 引言 大咯血原因很多 .炎症、支气管扩张、肺癌、肺结核、肺动静脉瘘等 .但因支气管动脉畸形引起的大咯血尚未见专题报道 .现将我院 1992年 10月份以来行数字减影血管造影 (DSA )检查 ,确诊支气管动脉畸形行支气管动脉栓塞(BAE)治疗大咯血术后并发症的预防与护理报道如下 :1 临床资料 6 (男 5 ,女 1)例大咯血患者 ,年龄 16~ 5 9岁 .均因无明显诱因 ,反复咯血而多次保守治疗 ,一次或 2 4h内咯血量为 40 0~ 10 0 0 m L ,病程最长 13a.入院后行 CT、纤维支气管镜、支气管碘油造影等栓查 ,均未见明显异常 ,后因保守治疗无效时行 D… 相似文献
107.
ABSTRACT. In children with myelodysplasia and a low lumbar or sacral level of spinal cord lesions detrusor hyperactivity with pressure fluctuations is an almost constant phenomenon contributing to incontinence. In thirteen children with this type of dysfunction the effect of adrenergic agonists and antagonists on bladder and urethral pressures were studied by means of intravesical and urethral pressure recordings during the normal bladder-filling phase. Intravenous infusion of noradrenaline during the bladder-filling phase slightly reduced detrusor hyperactivity and the urethral pressure was increased. Following i.m. injection of the alpha-adrenergic antagonist pheatolamine both the intravesical and proximal urethral pressures were reduced to about the same extent and the detrusor hyperactivity decreased. It is concluded that noradrenaline mainly changed urethral pressure while alpha-adrenergic blockade caused decreased tone in both the detrusor and the urethra as well as decreased detrusor hyperactivity. 相似文献
108.
BM Winklhofer-Roob DH Shmerling R Solèr J Briner 《Acta paediatrica (Oslo, Norway : 1992)》1992,81(8):637-640
The second child of healthy unrelated parents presented with chronic diarrhoea since the age of two months, initially associated with non-characteristic liver involvement. Recurrent infections, severe failure to thrive and various metabolic deficiencies complicated the further course, as well as profuse watery diarrhoea with elevated regulatory gut peptides, responding only to somatostatin analog treatment. At 22 months of age, intermittent cholestasis with permanently normal serum gamma-glutamyltransferase was evident. The child died of fulminant purulent meningitis at the age of three years six months. Liver histology showed intrahepatic cholestasis, bile duct paucity with focal proliferation as well as slight portal and intralobular fibrosis. The clinical, biochemical and histopathological findings were indicative of Byler's disease. 相似文献
109.
AC Fenton KL Woods R Leanage M Abu-Harb MI Levene DH Evans DJ Field 《Acta paediatrica (Oslo, Norway : 1992)》1992,81(6-7):498-503
Sick preterm infants may, under certain conditions, demonstrate blood pressure passive cerebral blood flow in response to changes in arterial carbon dioxide tension. Blood pressure in turn depends on cardiac output and peripheral resistance. A Doppler technique for assessing cardiac output compared favourably in terms of reproducibility to a thermodilution technique in a group of infants undergoing cardiac catheterization for congenital heart disease. Doppler was subsequently used to monitor changes in cardiac output following an increase in arterial carbon dioxide tension of 1 kPa in 25 ventilated preterm infants. Blood pressure increased significantly (p = 0.006). However, heart rate did not change significantly (p = 0.16) and, in addition, both stroke and minute volume decreased (p = 0.023, p = 0.02, respectively). This suggests that accompanying changes in components of peripheral resistance exert important effects on blood pressure in the preterm neonate in response to changes in arterial carbon dioxide tension. 相似文献
110.
Anagha Pradhan Karina Kielmann Himanshu Gupte Arun Bamne John DH Porter Sheela Rangan 《BMC public health》2010,10(1):263