全文获取类型
| 收费全文 | 2432941篇 |
| 免费 | 195539篇 |
| 国内免费 | 8219篇 |
专业分类
| 耳鼻咽喉 | 31961篇 |
| 儿科学 | 80038篇 |
| 妇产科学 | 68185篇 |
| 基础医学 | 339390篇 |
| 口腔科学 | 66613篇 |
| 临床医学 | 220581篇 |
| 内科学 | 489541篇 |
| 皮肤病学 | 57810篇 |
| 神经病学 | 201751篇 |
| 特种医学 | 95957篇 |
| 外国民族医学 | 708篇 |
| 外科学 | 369714篇 |
| 综合类 | 58046篇 |
| 现状与发展 | 4篇 |
| 一般理论 | 829篇 |
| 预防医学 | 195047篇 |
| 眼科学 | 53931篇 |
| 药学 | 170785篇 |
| 6篇 | |
| 中国医学 | 5007篇 |
| 肿瘤学 | 130795篇 |
出版年
| 2018年 | 26459篇 |
| 2017年 | 20491篇 |
| 2016年 | 23826篇 |
| 2015年 | 26647篇 |
| 2014年 | 37559篇 |
| 2013年 | 56167篇 |
| 2012年 | 72369篇 |
| 2011年 | 77517篇 |
| 2010年 | 47012篇 |
| 2009年 | 45330篇 |
| 2008年 | 71968篇 |
| 2007年 | 76345篇 |
| 2006年 | 77590篇 |
| 2005年 | 75286篇 |
| 2004年 | 71919篇 |
| 2003年 | 69165篇 |
| 2002年 | 66229篇 |
| 2001年 | 118598篇 |
| 2000年 | 121600篇 |
| 1999年 | 101264篇 |
| 1998年 | 29838篇 |
| 1997年 | 26869篇 |
| 1996年 | 27626篇 |
| 1995年 | 27024篇 |
| 1994年 | 24867篇 |
| 1993年 | 23384篇 |
| 1992年 | 80255篇 |
| 1991年 | 77471篇 |
| 1990年 | 74393篇 |
| 1989年 | 70876篇 |
| 1988年 | 65448篇 |
| 1987年 | 64117篇 |
| 1986年 | 60260篇 |
| 1985年 | 57894篇 |
| 1984年 | 44161篇 |
| 1983年 | 37291篇 |
| 1982年 | 23106篇 |
| 1981年 | 20649篇 |
| 1980年 | 19234篇 |
| 1979年 | 39546篇 |
| 1978年 | 28312篇 |
| 1977年 | 23721篇 |
| 1976年 | 22002篇 |
| 1975年 | 22791篇 |
| 1974年 | 27098篇 |
| 1973年 | 26068篇 |
| 1972年 | 24341篇 |
| 1971年 | 22303篇 |
| 1970年 | 20820篇 |
| 1969年 | 19375篇 |
排序方式： 共有10000条查询结果，搜索用时 15 毫秒
121.
Renal Denervation for Treatment of Cardiac Arrhythmias: State of the Art and Future Directions 
下载免费PDF全文
下载免费PDF全文 JEDRZEJ KOSIUK M.D. SEBASTIAN HILBERT M.D. EVGENY POKUSHALOV M.D. GERHARD HINDRICKS M.D. Ph.D. JONATHAN S. STEINBERG M.D. ANDREAS BOLLMANN M.D. Ph.D. 《Journal of cardiovascular electrophysiology》2015,26(2):233-238
Renal Denervation for Treatment of Cardiac Arrhythmias . It has now been more than a quarter of a century since modulation of the sympathetic nervous system was proposed for the treatment of cardiac arrhythmias of different origins. But it has also been some time since some of the early surgical attempts have been abandoned. With the development of ablation techniques, however, new approaches and targets have been recently introduced that have revolutionized our way of thinking about sympathetic modulation. Renal nerve ablation technology is now being successfully used for the treatment of resistant hypertension, but the indication spectrum might broaden and new therapeutic options might arise in the near future. This review focuses on the possible impact of renal sympathetic system modulation on cardiac arrhythmias, the current evidence supporting this approach, and the ongoing trials of this method in electrophysiological laboratories. We will discuss the potential roles that sympathetic modulation may play in the future. 相似文献
122.
123.
124.
125.
126.
127.
Hanna Lee Mary K. Tan Andrew T. Yan Paul Angaran Paul Dorian Claudia Bucci Jean C. Gregoire Alan D. Bell Martin S. Green Peter L. Gross Allan Skanes Charles R. Kerr L. Brent Mitchell Jafna L. Cox Vidal Essebag Brett Heilbron Krishnan Ramanathan Carl Fournier Shaun G. Goodman 《The Canadian journal of cardiology》2019,35(2):160-168
Background
Physicians treating nonvalvular atrial fibrillation (AF) assess stroke and bleeding risks when deciding on anticoagulation. The agreement between empirical and physician-estimated risks is unclear. Furthermore, the association between patient and physician sex and anticoagulation decision-making is uncertain.Methods
We pooled data from 2 national primary care physician chart audit databases of patients with AF (Facilitating Review and Education to Optimize Stroke Prevention in Atrial Fibrillation and Coordinated National Network to Engage Physicians in the Care and Treatment of Patients with Atrial Fibrillation Chart Audit) with a combined 1035 physicians (133 female, 902 male) and 10,927 patients (4567 female and 6360 male).Results
Male physicians underestimated stroke risk in female patients and overestimated risk in male patients. Female physicians estimated stroke risk well in female patients but underestimated the risk in male patients. Risk of bleeding was underestimated in all. Despite differences in risk assessment by physician and patient sex, > 90% of patients received anticoagulation across all subgroups. There was modest agreement between physician estimated and calculated (ie, CHADS2 score) stroke risk: Kappa scores were 0.41 (0.35-0.47) for female physicians and 0.34 (0.32-0.36) for male physicians.Conclusions
Our study is the first to examine the association between patient and physician sex influences and stroke and bleeding risk estimation in AF. Although there were differences in agreement between physician estimated stroke risk and calculated CHADS2 scores, these differences were small and unlikely to affect clinical practice; further, despite any perceived differences in the accuracy of risk assessment by sex, most patients received anticoagulation. 相似文献128.
129.
C. Jacquet F. Goehringer E. Baux J.A. Conrad M.O. Ganne Devonec J.L. Schmutz G. Mathey H. Tronel T. Moulinet I. Chary-Valckenaere T. May C. Rabaud 《Médecine et maladies infectieuses》2019,49(2):112-120
Objective
The teaching hospital of Nancy, France, implemented a specific multidisciplinary care pathway (French acronym AMDPL) to improve the management of patients presenting with Lyme borreliosis (LB) suspicion. We aimed to assess the first year of activity of this care pathway.Patients and methods
We included all patients managed in the AMDPL pathway from November 1, 2016 to October 31, 2017. The first step was a dedicated Lyme disease consultation with an infectious disease specialist. Following this consultation, the LB diagnosis was either confirmed and adequate treatment was prescribed, or a differential diagnosis was established and patients received adequate management, or further investigations were required and patients were offered multidisciplinary management as part of a day hospitalization.Results
A total of 468 patients were included. LB diagnosis was confirmed in 15% of patients (69/468), 49% of patients received a differential diagnosis, and 26% (122/468) of patients had the LB diagnosis ruled out without receiving any other diagnosis.Conclusions
This is to our knowledge the first multidisciplinary center implemented in France for the management of patients presenting with LB suspicion related to polymorphous signs and symptoms. Several diagnoses could be confirmed or corrected, although some symptoms and complaints could not be explained. This cohort could improve our knowledge of LB and its differential diagnoses. 相似文献130.