全文获取类型
收费全文 | 481篇 |
免费 | 21篇 |
国内免费 | 75篇 |
专业分类
儿科学 | 7篇 |
妇产科学 | 7篇 |
基础医学 | 34篇 |
口腔科学 | 12篇 |
临床医学 | 60篇 |
内科学 | 92篇 |
皮肤病学 | 38篇 |
神经病学 | 18篇 |
特种医学 | 89篇 |
外科学 | 41篇 |
综合类 | 80篇 |
预防医学 | 8篇 |
药学 | 70篇 |
中国医学 | 1篇 |
肿瘤学 | 20篇 |
出版年
2022年 | 4篇 |
2021年 | 3篇 |
2019年 | 3篇 |
2018年 | 8篇 |
2017年 | 6篇 |
2016年 | 7篇 |
2014年 | 2篇 |
2013年 | 11篇 |
2012年 | 8篇 |
2011年 | 9篇 |
2010年 | 23篇 |
2009年 | 20篇 |
2008年 | 18篇 |
2007年 | 59篇 |
2006年 | 29篇 |
2005年 | 16篇 |
2004年 | 19篇 |
2003年 | 16篇 |
2002年 | 10篇 |
2001年 | 12篇 |
2000年 | 16篇 |
1999年 | 12篇 |
1998年 | 25篇 |
1997年 | 24篇 |
1996年 | 27篇 |
1995年 | 19篇 |
1994年 | 11篇 |
1993年 | 20篇 |
1992年 | 4篇 |
1991年 | 6篇 |
1989年 | 13篇 |
1988年 | 4篇 |
1987年 | 12篇 |
1986年 | 9篇 |
1985年 | 15篇 |
1984年 | 3篇 |
1983年 | 7篇 |
1982年 | 8篇 |
1981年 | 10篇 |
1980年 | 6篇 |
1978年 | 3篇 |
1977年 | 6篇 |
1976年 | 5篇 |
1975年 | 6篇 |
1973年 | 2篇 |
1964年 | 3篇 |
1963年 | 2篇 |
1962年 | 2篇 |
1958年 | 2篇 |
1957年 | 3篇 |
排序方式: 共有577条查询结果,搜索用时 15 毫秒
31.
Mucormycosis is a rare fungal infection of childhood, occurring mainly in
patients with chronic illnesses such as diabetes and malignancies. The
fungus seldom grows in culture and confirmation of the diagnosis depends on
histologic examination of infected tissues. To date, the reported natural
history of the disease has been rapid progression and a fatal outcome.
Therefore, the importance of early diagnosis by tissue biopsy and early
treatment with surgical debridement and systemic antifungal therapy cannot
be overemphasized. The pulmonary system is the most common site for
mucormycosis in patients with leukemia. We report what we believe to be the
first successfully treated case of isolated muscular mucormycosis occurring
in a child with biphenotypic acute leukemia. The diagnosis was made
promptly by tissue examination at the time of surgical debridement. The
patient was also given systemic amphotericin-B therapy.
相似文献
32.
KM FOCK JY KANG HS NG TM NG KA GWEE CC LIM 《Journal of gastroenterology and hepatology》1995,10(4):379-382
Roxatidine acetate, a new H2 receptor antagonist, was compared with ranitidine in the treatment of duodenal ulcers in a double-blind multicentre study. Eighty-four patients with endoscopically proven duodenal ulcer were randomized to receive 150 mg roxatidine acetate or 300 mg ranitidine at bedtime. Repeat endoscopy was performed after 4 weeks (25–33 days) and if the ulcer had not healed, another endoscopy was performed after a further 4 weeks of treatment. Using per protocol analysis 73.6% of ulcers treated with roxatidine healed at 4 weeks compared to 72.2% of ulcers treated with ranitidine (P=NS). The healing rates at 8 weeks were 92% with roxatidine and 83.3% with ranitidine (P=NS). Using equivalence tests, the healing rate of roxatidine was found to be equivalent to that of ranitidine within a 20% region. Roxatidine users took significantly less antacids than ranitidine users (P < 0.05). There were no significant adverse effects due to roxatidine or ranitidine. Roxatidine is a safe effective drug in the treatment of duodenal ulcers with a healing rate comparable to that of ranitidine. 相似文献
33.
34.
Thoracic wall involvement by Hodgkin disease and non-Hodgkin lymphoma: CT evaluation 总被引:6,自引:0,他引:6
Thoracic computed tomographic (CT) scans of 250 patients with newly diagnosed or recurrent lymphoma revealed thoracic wall involvement in 24 patients (11 with Hodgkin disease, 13 with non-Hodgkin lymphoma). Thoracic wall involvement occurred without contiguous mediastinal or parenchymal involvement in 17 patients. Of these, 13 patients had masses beneath the pectoralis muscles or within the breast, and four had masses arising from the ribs. Five additional patients had mediastinal masses with thymic involvement and parasternal extension through the thoracic wall. Pulmonary parenchymal lymphoma with thoracic wall invasion was noted in the remaining two patients. In five of nine patients receiving radiation therapy, treatment plans were modified by CT demonstration of thoracic wall lymphoma. 相似文献
35.
蛇胆汁中牛磺胆酸含量测定方法的比较研究 总被引:2,自引:0,他引:2
目的:比较分析了3种测定蛇胆汁中主要成分牛磺胆酸含量的方法,制定科学合理统一的质量标准。方法:用薄层层析-磷钼酸比色法、薄层扫描法及高效液相色谱法对蛇胆汁中主要成分牛磺胆酸进行测定,并将结果进行比较分析。结果:薄层层析-磷钼酸比色法、薄层扫描法及高效液相色谱法的含量测定结果有一定差异,平均回收率分别为97.48%,98.51%和100.34%,RSD分别为4.6%,4.3%和1.5%。结论:高效液 相似文献
36.
商陆多糖Ⅰ联合白细胞介素2对小鼠脾细胞杀瘤活性的影响 总被引:2,自引:0,他引:2
商陆多糖Ⅰ(PAP-I),0.3~3μg·ml-1和小鼠脾细胞培养3~5d可显著增强其杀伤P815肿瘤细胞活性及IL-2(250~500IU·ml-1)诱导的LAK细胞活性,最适浓度为1μg·ml-1。PAP-I及IL-2和脾细胞培养的上清液对P815肿瘤细胞无细胞毒作用,但能增强脾细胞及LAK细胞杀瘤活性。PAP-I,5,10及50mg·kg-1,ip可增强脾细胞杀伤P815和L929细胞的活性及IL-2诱导的LAK细胞活性。 相似文献
37.
38.
玻璃体切除术治疗外伤性眼内炎62例 总被引:2,自引:1,他引:2
0 引言 外伤性眼内炎是眼外伤的常见并发症 ,对视力及眼球威协极大 .由于病原体随致伤物直接进入眼内 ,在眼内和玻璃体繁殖 ,产生剧烈炎症反应 ,对眼内组织造成严重破坏 .如不及时而有效的控制 ,终使视力丧失 ,眼球萎缩 .近年随着现代玻璃体手术的发展 ,外伤性眼内炎的治愈率明显提高 .现将我科收治的 6 2例报告如下 .1 对象和方法1 .1 对象 1 996 - 0 6 / 1 998- 0 6我院连续收治 6 2例外伤性眼内炎 ,其中男 5 0例 ,女 1 2例 ,年龄 2~ 45岁 ,平均 1 6 .5岁 .1 4岁以下儿童 38例 ,占 6 1 .3% .以致伤原因分类 :角膜穿通伤30例 ,巩膜穿… 相似文献
39.
40.
The management of stage I--II Hodgkin's disease with irradiation alone or combined modality therapy: the Stanford experience 总被引:1,自引:0,他引:1
At Stanford University, between 1968 and 1978, 230 patients with pathologic stage I--II Hodgkin's disease were treated on prospective clinical trials with either irradiation alone or irradiation followed by 6 cycles of adjuvant combination chemotherapy. The actuarial survival at 10 yr was 84% for patients in either treatment group. Freedom from relapse at 10 yr was 77% among patients treated with irradiation alone and 84% after treatment with combined modality therapy [p(Gehan) = 0.09]. Freedom from second relapse at 10 yr was 89% and 94%, respectively [p(Gehan) = 0.56]. Several prognostic factors were evaluated in order to identify patients at high risk for relapse or with poor ultimate survival after initial treatment with irradiation alone. Systemic symptoms, histologic subtype, age, and limited extranodal involvement (E-lesions) did not affect the prognosis of patients and failed to identify patients whose survival could be improved by the routine use of combined modality therapy. Patients with large mediastinal masses (mediastinal mass ratio greater than or equal to 1/3) had a significantly poorer freedom from relapse when treated with irradiation alone than when treated initially with combined modality therapy [45% versus 81% at 10 yr, p(Gehan) = 0.03). The 10-yr survival of these patients, however, was not significantly different (84% versus 74%). The implications of these observations on the management of patient with early stage Hodgkin's disease are discussed. 相似文献