全文获取类型
收费全文 | 24503篇 |
免费 | 1416篇 |
国内免费 | 135篇 |
专业分类
耳鼻咽喉 | 249篇 |
儿科学 | 627篇 |
妇产科学 | 502篇 |
基础医学 | 3681篇 |
口腔科学 | 1043篇 |
临床医学 | 2182篇 |
内科学 | 5682篇 |
皮肤病学 | 669篇 |
神经病学 | 2156篇 |
特种医学 | 563篇 |
外科学 | 2212篇 |
综合类 | 50篇 |
一般理论 | 10篇 |
预防医学 | 2340篇 |
眼科学 | 477篇 |
药学 | 1658篇 |
中国医学 | 112篇 |
肿瘤学 | 1841篇 |
出版年
2024年 | 33篇 |
2023年 | 255篇 |
2022年 | 605篇 |
2021年 | 1024篇 |
2020年 | 612篇 |
2019年 | 819篇 |
2018年 | 932篇 |
2017年 | 643篇 |
2016年 | 769篇 |
2015年 | 839篇 |
2014年 | 1108篇 |
2013年 | 1406篇 |
2012年 | 2198篇 |
2011年 | 2291篇 |
2010年 | 1202篇 |
2009年 | 987篇 |
2008年 | 1694篇 |
2007年 | 1632篇 |
2006年 | 1483篇 |
2005年 | 1372篇 |
2004年 | 1193篇 |
2003年 | 1007篇 |
2002年 | 884篇 |
2001年 | 97篇 |
2000年 | 72篇 |
1999年 | 88篇 |
1998年 | 125篇 |
1997年 | 106篇 |
1996年 | 87篇 |
1995年 | 67篇 |
1994年 | 56篇 |
1993年 | 58篇 |
1992年 | 41篇 |
1991年 | 37篇 |
1990年 | 27篇 |
1989年 | 31篇 |
1988年 | 22篇 |
1987年 | 11篇 |
1986年 | 23篇 |
1985年 | 17篇 |
1984年 | 26篇 |
1983年 | 15篇 |
1982年 | 17篇 |
1981年 | 10篇 |
1980年 | 3篇 |
1979年 | 7篇 |
1978年 | 5篇 |
1977年 | 6篇 |
1974年 | 2篇 |
1973年 | 2篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
992.
993.
Guilherme Silva de Mendonça RN Denis Fabiano de Souza RN Ana Cláudia de Alvarenga Cunha Brunelli RN Cristina Ila de Oliveira Peres RN Ercilhana Gonçalves Batista Freitas RN Gabriela Nolasco Lacerda RN Michelle Caixeta Dorneles RN Aldo José Peixoto MD Sebastião Rodrigues Ferreira‐Filho MD 《Journal of clinical hypertension (Greenwich, Conn.)》2018,20(9):1285-1293
Data on arterial stiffness in older populations, according to blood pressure (BP) levels, are scarce in Brazil. The objective of this study was to establish reference values for core measures of arterial stiffness, including carotid‐femoral pulse wave velocity (cf‐PWV) and aortic augmentation index (AIx), in a cohort of older individuals with normotension (NT) and hypertension. Cross‐sectional analysis was performed with applanation tonometry data from 1192 patients aged 60 years or older. The authors classified patients according to their BP levels as having NT, controlled hypertension (CH), and uncontrolled hypertension (UH). The cf‐PWV values were 9.11 ± 0.16 m/s (NT), 9.12 ± 0.18 m/s (CH), and 9.42 ± 2.2 m/s (UH) (P < 0.005; UH vs NT and CH). The AIx was 33.3% for the entire cohort and similar across all groups. The cf‐PWV increased with age but reached a ceiling at 75 years. Compared with men, women had a higher AIx but similar cf‐PWV levels. In conclusion, the markers of arterial stiffness were similar among individuals with NT/CH and higher among individuals with UH. 相似文献
994.
995.
Mitral regurgitation severity correlates with symptoms and extent of left atrial dysfunction: Effect of mitral valve repair 下载免费PDF全文
Matteo Lisi MD Matteo Cameli MD Cristina Di Tommaso MD Valeria Curci MD Rosanna Reccia MD Flavio D'ascenzi MD Marta Focardi PhD Massimo Maccherini MD Mario Chiavarelli MD Gianfranco Lisi MD Per Lindqvist PhD Sergio Mondillo MD Michael Henein MD PhD 《Journal of clinical ultrasound : JCU》2018,46(1):32-40
996.
Correspondence Between NANDA International Nursing Diagnoses and Outcomes as Proposed by the Nursing Outcomes Classification 下载免费PDF全文
Emilia Campos de Carvalho PhD RN Aline Helena Appoloni Eduardo PhD RN Adilson Romanzini RN Talita Prado Simão RN Cristina Mara Zamarioli RN Danielle Cristina Garbuio RN Tracy Heather Herdman PhD RN FNI 《International journal of nursing knowledge》2018,29(1):66-78
The accurate identification of the nursing diagnoses and the corresponding measurement of their indicators will depend on the elements in the standardized language systems.
OBJECTIVE
To analyze the correspondence between elements of four NANDA‐I nursing diagnoses and outcomes suggested by the nursing outcomes classification (NOC) for the resolution of these diagnoses.METHOD
A methodological study consisting of cross‐mapping was performed in the first stage between definitions, defining characteristics (DCs), and related factors (RFs) of impaired oral mucous membrane, impaired tissue integrity, spiritual distress, and delayed surgical recovery and outcome definitions and indicators to measure results of diagnoses resolution and an analysis of its relevance by experts in the second stage.RESULTS
It found partial correspondence between outcome indicators, DCs, RFs, and definitions.CONCLUSION
The data evidence the relevance of this review for a reliable application of these taxonomies and demonstrated partial correspondence between concepts analyzed. A identificação precisa dos diagnósticos de enfermagem e a medida correspondente dos seus indicadores dependerá dos elementos nos sistemas de linguagem padronizados.OBJETIVO
Foi analisar a correspondência entre os elementos de quatro NANDA‐I diagnósticos de enfermagem e os resultados sugeridos pelo NOC para a resolução destes diagnósticos.MÉTODO
um estudo metodológico que consiste em cross‐mapping foi realizado em uma primeira fase entre as definições, características definidoras e fatores relacionados de Mucosa oral prejudicada, Integridade tissular prejudicada, Sofrimento espiritual e Recuperação cirúrgica retardada e as definições dos resultados indicados para a resolução destes diagnósticos; na segunda fase, foi realizada uma análise desta concordância por especialistas.RESULTADOS
correspondência parcial entre as definições dos diagnósticos e dos resultados, características definidoras e fatores relacionados.CONCLUSÃO
Os resultados evidenciam a relevância dessa avaliação para uma aplicação confiável destas taxonomias e demonstrou a correspondência parcial entre os conceitos analisados. 相似文献997.
The various clinical phenotypes in β-thalassemias have stimulated the study of genetic factors that could modify the manifestations of these diseases. We examined 21 patients with β-thalassemia (β-thal) in order to identify some genetic modifying factors: β-thalassemia mutations, HBG2:g.-158C>T polymorphism, α-globin gene deletions and (AT)xNz(AT)y motif within the hypersensitive site 2-locus control region (HS2-LCR). In the 42 alleles analyzed, the most frequent mutations observed were HBB:c.92+6T>C (30.9%), HBB:c.118C>T (16.7%), HBB:c.93-21G>A (11.9%) and HBB:c.92+1G>A (4.8%); this finding is in accordance with previous data of the Brazilian population. The other genetic factors analyzed showed no relation with the severity of the disease. For the first time in Brazil, we report HBB:c.93-2A>G and HBB:c.114G>A mutations on the β-globin gene, both in a heterozygous state. This is also the first study to analyze the HS2-LCR in β-thalassemic individuals in the Brazilian population. 相似文献
998.
999.
Arnold Criel Gregor Verhoef Robert Vlietinck Cristina Mecucci Johan Billiet Lucienne Michaux Peter Meeus ries Louwagie Angeline Van Orshoven Achiel Van Hoof Mark Boogaerts Herman Van den Berghe & Chris De Wolf-Peeters 《British journal of haematology》1997,97(2):383-391
We analysed a group of 390 patients, diagnosed with chronic lymphocytic leukaemia (CLL). Cases were subclassified as morphologically typical and atypical CLL according to the criteria of the FAB proposal. Typical CLL cases were mostly diagnosed at a low-risk stage (Binet A/Rai 0), required no immediate treatment and expected a long survival; atypical CLL cases mostly presented at a more advanced risk stage (Binet B/Rai I–II), usually required immediate treatment and their survival was shorter. Moreover, clinical staging was of prognostic significance in typical but not in atypical cases. In typical CLL, del(11q) was the most common chromosomal abnormality (21%) whereas in atypical CLL trisomy 12 was found in about 65% of the cases documented with an abnormal karyotype. Although chromosomal abnormalities were associated with a poor survival in typical CLL, they are of no prognostic significance in atypical CLL. Based on these data, we conclude that subtyping CLL by morphology enables the identification of two groups of cases, each characterized by a specific clinical presentation, different cytogenetic abnormalities and prognostic parameters. We speculate that these two groups may represent two related, but different, diseases with different prognostic parameters and a different survival. 相似文献
1000.
Tetracycline and streptomycin resistance genes, transposons, and plasmids in Salmonella enterica isolates from animals in Italy 总被引:5,自引:0,他引:5 下载免费PDF全文
Pezzella C Ricci A DiGiannatale E Luzzi I Carattoli A 《Antimicrobial agents and chemotherapy》2004,48(3):903-908
Fifty-eight multidrug-resistant Salmonella enterica strains of 20 serotypes, isolated from animal sources in Italy, were analyzed for tet(A) and strA-strB, conferring tetracycline and streptomycin resistance, respectively. The strA and strB genes were highly prevalent in Salmonella strains of our collection, being detected in 84% of the streptomycin-resistant strains. In many strains, the strA and strB genes were linked to a particular Tn5393-derivative transposon characterized by the presence of the insertion sequence IS1133, previously identified only in the plant pathogen Erwinia amylovora. Sixty-eight percent of the tetracycline-resistant strains were tet(A) positive, indicating that this gene is widely diffused in Salmonella strains circulating in animals in Italy. Most of the tet(A) genes were localized within a deleted Tn1721 transposon variant. Two prevalent repN and repI1 resistance plasmids were identified in Salmonella isolates of our collection. 相似文献