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Reza Saeidi Pour DR MED DENT Otto Zuhr DR MED DENT Markus Hürzeler PROF DR MED DENT Otto Prandtner MDT Caroline Freitas Rafael Daniel Edelhoff PROF DR MED DENT Anja Liebermann DR MED DENT 《Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]》2017,29(2):93-101
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A systematic review of risk of HIV transmission through biting or spitting: implications for policy 下载免费PDF全文
Objectives
The perceived threat of HIV transmission through spitting and biting is evidenced by the increasing use of “spit hoods” by Police Forces in the UK. In addition, a draft parliamentary bill has called for increased penalties for assaults on emergency workers, citing the risk of communicable disease transmission as one justification. We aimed to review literature relating to the risk of HIV transmission through biting or spitting.Methods
A systematic literature search was conducted using Medline, Embase and Northern Lights databases and conference websites using search terms relating to HIV, AIDS, bite, spit and saliva. Inclusion and exclusion criteria were applied to identified citations. We classified plausibility of HIV transmission as low, medium, high or confirmed based on pre‐specified criteria.Results
A total of 742 abstracts were reviewed, yielding 32 articles for full‐text review and 13 case reports/series after inclusion and exclusion criteria had been applied. There were no reported cases of HIV transmission related to spitting and nine cases identified following a bite, in which the majority occurred between family (six of nine), in fights involving serious wounds (three of nine), or to untrained first‐aiders placing fingers in the mouth of someone having a seizure (two of nine). Only four cases were classified as highly plausible or confirmed transmission. None related to emergency workers and none were in the UK.Conclusions
There is no risk of transmitting HIV through spitting, and the risk through biting is negligible. Post‐exposure prophylaxis is not indicated after a bite in all but exceptional circumstances. Policies to protect emergency workers should be developed with this evidence in mind. 相似文献47.
Nonsuicidal Self‐injury as a Risk Factor for Purging Onset: Negatively Reinforced Behaviours that Reduce Emotional Distress 下载免费PDF全文
Elizabeth N. Riley Heather A. Davis Jessica L. Combs Carol E. Jordan Gregory T. Smith 《European eating disorders review》2016,24(1):78-82
Both nonsuicidal self‐injury (NSSI) and purging behaviour are thought to involve harm to the self. The acquired capability for self‐harm model holds that engaging in one self‐harming behaviour increases the capability to tolerate harm to the self, thus increasing risk for engaging on other such behaviours. In addition, both behaviours are thought to serve the similar function of relief from distress. We thus tested whether engagement in one of these behaviours predicts the subsequent onset of the other. In a longitudinal design, 1158 first‐year college women were assessed for purging and NSSI at two time points. Engagement in NSSI at time 1 predicted the college onset of purging behaviour 9 months later (OR = 2.20, p < .04, CI = 1.07–4.19) beyond prediction from time 1 binge behaviour, and purging behaviour at time 1 predicted the subsequent onset of NSSI (OR = 6.54, p < .01, CI = 1.71–25.04). These findings are consistent with the acquired capability for harm model and with the possibility that the two behaviours serve a similar function. Copyright © 2015 John Wiley & Sons, Ltd and Eating Disorders Association. 相似文献
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Kevin J Zwezdaryk Joseph A Combs Cindy A Morris Deborah E Sullivan 《World Journal of Virology》2016,5(4):144-154
The Wnt/β-catenin signaling pathway is instrumental in successful differentiation and proliferation of mammalian cells. It is therefore not surprising that the herpesvirus family has developed mechanisms to interact with and manipulate this pathway. Successful coexistence with the host requires that herpesviruses establish a lifelong infection that includes periods of latency and reactivation or persistence. Many herpesviruses establish latency in progenitor cells and viral reactivation is linked to host-cell proliferation and differentiation status. Importantly, Wnt/β-catenin is tightly connected to stem/progenitor cell maintenance and differentiation. Numerous studies have linked Wnt/β-catenin signaling to a variety of cancers, emphasizing the importance of Wnt/β-catenin pathways in development, tissue homeostasis and disease. This review details how the alpha-, beta-, and gammaherpesviruses interact and manipulate the Wnt/β-catenin pathway to promote a virus-centric agenda. 相似文献
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