全文获取类型
收费全文 | 19955篇 |
免费 | 1815篇 |
国内免费 | 43篇 |
专业分类
耳鼻咽喉 | 212篇 |
儿科学 | 625篇 |
妇产科学 | 468篇 |
基础医学 | 2792篇 |
口腔科学 | 177篇 |
临床医学 | 2747篇 |
内科学 | 3956篇 |
皮肤病学 | 289篇 |
神经病学 | 1966篇 |
特种医学 | 462篇 |
外科学 | 2087篇 |
综合类 | 233篇 |
一般理论 | 20篇 |
预防医学 | 2534篇 |
眼科学 | 283篇 |
药学 | 1501篇 |
中国医学 | 21篇 |
肿瘤学 | 1440篇 |
出版年
2023年 | 256篇 |
2022年 | 323篇 |
2021年 | 660篇 |
2020年 | 430篇 |
2019年 | 708篇 |
2018年 | 722篇 |
2017年 | 491篇 |
2016年 | 534篇 |
2015年 | 564篇 |
2014年 | 681篇 |
2013年 | 995篇 |
2012年 | 1493篇 |
2011年 | 1484篇 |
2010年 | 758篇 |
2009年 | 691篇 |
2008年 | 1075篇 |
2007年 | 1160篇 |
2006年 | 1119篇 |
2005年 | 1044篇 |
2004年 | 869篇 |
2003年 | 865篇 |
2002年 | 792篇 |
2001年 | 269篇 |
2000年 | 289篇 |
1999年 | 291篇 |
1998年 | 180篇 |
1997年 | 175篇 |
1996年 | 135篇 |
1995年 | 117篇 |
1994年 | 82篇 |
1993年 | 110篇 |
1992年 | 194篇 |
1991年 | 200篇 |
1990年 | 188篇 |
1989年 | 174篇 |
1988年 | 162篇 |
1987年 | 141篇 |
1986年 | 133篇 |
1985年 | 115篇 |
1984年 | 92篇 |
1983年 | 92篇 |
1982年 | 75篇 |
1981年 | 87篇 |
1980年 | 71篇 |
1979年 | 74篇 |
1978年 | 62篇 |
1977年 | 56篇 |
1976年 | 48篇 |
1974年 | 43篇 |
1972年 | 44篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
Pancreatic Panniculitis Associated with Allograft Pancreatitis and Rejection in a Simultaneous Pancreas–Kidney Transplant Recipient 总被引:1,自引:0,他引:1
J. L. Pike J. C. Rice R. L. Sanchez E. B. Kelly B. C. Kelly 《American journal of transplantation》2006,6(10):2502-2505
Pancreatic panniculitis is an uncommon condition that can occur in association with pancreatic disease. We present a case of pancreatic panniculitis in a female pancreas-kidney transplant recipient 5 months post-transplant. The patient was on standard immunosuppressive medications and had acute rejection of her renal allograft. The diagnosis of allograft pancreatitis and rejection presenting with pancreatic panniculitis was supported clinically, histopathologically and by laboratory and imaging data. This is the fourth case of pancreatic panniculitis occurring in a transplant recipient and the first in a simultaneous pancreas-kidney transplant recipient. It is also the first case associated with allograft rejection. Clinicians should be aware that pancreatic panniculitis may be a manifestation of underlying allograft pancreatic disease. 相似文献
12.
Anne Pavy-Le Traon Richard L Hughson Claire Thalamas Monique Galitsky Nelly Fabre Olivier Rascol Jean-Michel Senard 《Movement disorders》2006,21(12):2122-2126
Patients with multiple system atrophy (MSA) present large changes in blood pressure (BP) due to autonomic disturbances. We analyzed how this change may influence dynamic cerebral autoregulation (DCA). Simultaneous recordings of arterial BP (Finapres) and middle cerebral artery (MCA) blood flow velocity (BFV) (transcranial Doppler) were performed in 10 patients with MSA (61 +/- 12 yr of age) and 12 healthy volunteers (61 +/- 11 yr of age): cerebral BFV response to oscillations in mean BP was studied in the supine position by cross-spectral analysis of mean BP and mean MCA BFV. The DCA was also studied during the decrease in BP the first seconds when standing up from a sitting position by the assessment of the cerebrovascular resistance index (CR; mean BP/mean MCA BFV ratio). The MCA BFV/BP cross-spectral analysis showed a phase for the mid-frequency band (0.07-0.2 Hz) significantly larger in MSA, suggesting more active autoregulation in response to larger changes in BP. Changes in CR reflecting the rate of autoregulation, when standing did not differ between the two groups. These data suggest that dynamic cerebral autoregulation is preserved in MSA. 相似文献
13.
Reliable procedure for the production of 1-[(11)C]acetate in GMP conditions was developed based on a combination of the captive-solvent Grignard reaction conducted in the sterile catheter followed by the convenient solid-phase extraction purification on a series of ion-exchange cartridges. The described procedure proved to be reliable in more than 30 patient productions. The process provides stable radiochemical yields (65% EOB) of sodium acetate (1-[(11)C]) of the Ph.Eur. quality (radiochemical purity better than 95%) in a short time (5 min). 相似文献
14.
Claire M Rickard Brigit L Roberts Jonathon Foote Matthew R McGrail 《Dimensions of critical care nursing》2006,25(5):234-242
Research coordinators in intensive care are a growing specialty about which little is known. This cross-sectional study surveyed the Australia and New Zealand Intensive Care Research Coordinators' Group (n = 49) regarding demographics, education, employment history, job structure, and role content. Most research coordinators were highly qualified and experienced nurses who undertake pharmaceutical trials, multicenter projects, departmental medical and nursing research, audits and data registries, and their own projects. 相似文献
15.
C. R. Irwin T. Myrillas M. Smyth J. Doogan C. Rice S. L. Schor 《Journal of oral pathology & medicine》1998,27(6):255-259
Fibroblasts incorporated within collagen gels induce a cell-mediated contraction of the gel to form a three-dimensional, tissue-like structure by a mechanism thought to mimic wound contraction in vivo . In this study a gel contraction model was used to investigate the ability of fibroblasts derived from adult gingiva, adult skin and fetal skin to organise a collagen matrix. In addition the effects of interleukin-1β (IL-1β) on the contraction process was also investigated. Over the concentration range 5-50 U/ml, IL-1β induced a statistically significant inhibition of gel contraction in all fibroblast cell types ( P <0.05), although fetal fibroblasts appeared least responsive and gingival fibroblasts most responsive to the inhibitory effects of this cytokine. Comparison of gel contraction by the different fibroblast strains indicated that fetal and gingival fibroblasts shared similar contraction kinetics. For the adult skin fibroblasts, three of five strains studied showed significantly diminished levels of gel contraction compared to fetal and gingival cells. This apparent difference in fibroblast phenotype may, at least in part, explain the fetal-like wound healing pattern seen in the oral mucosa. 相似文献
16.
J.-P. Coudereau Marcel Debray Claire Monier Jean-Marie Bourre Henriette Frances 《Psychopharmacology》1997,130(2):117-123
Morphine (8–100 mg/kg IP) induces place preference conditioning in mice. The effect of two different periods of isolation
(15 and 30 days) was examined. Mice isolated for 15 days but not 30 days exhibited place preference conditioning to morphine
(8 mg/kg). After 30 days of isolation morphine could not induce place preference conditioning with the following doses (8, 16, 64, 100 mg/kg).
Social regrouping of male mice previously isolated for 30 days with naive female mice for 15 or 30 days resulted in a reappearance
of the conditioned place preference to morphine (16 mg/kg). The specificity of this associative deficit was examined by testing
learning in isolated compared to non-isolated mice in two distinct settings: escape learning in the Morris water maze and
passive avoidance acquisition and retention. On the Morris water maze isolated mice did not differ from non-isolated mice
regarding place learning, the probe trial or extinction. Isolated mice were unimpaired in passive avoidance acquisition and
retention. It was concluded that the deficits in place preference conditioning were not the result of a global learning impairment
in isolated mice.
Received: 10 April 1996 /Final version: 20 September 1996 相似文献
17.
S de Bustros J T Thompson R G Michels T A Rice B M Glaser 《The British journal of ophthalmology》1988,72(9):692-695
We used vitreous surgery to remove idiopathic epiretinal membranes from the macular area in 70 consecutive cases. The abnormal tissue was successfully removed in each case. Vision improved postoperatively in 61 eyes (87%), remained unchanged in six eyes (9%), and worsened in three eyes (4%). However, at the time of final examination vision was improved in only 47 eyes (67%), primarily because of the occurrence or progression of nuclear sclerosis, which occurred in 38 of 60 phakic eyes (63%). Four preoperative factors were associated with final visual acuity of 20/60 or better: (1) initial vision of 20/100 or better, (2) shorter preoperative duration of blurred vision, (3) thin epiretinal membrane, and (4) absence of traction retinal detachment. 相似文献
18.
19.
20.
Working memory after severe traumatic brain injury. 总被引:1,自引:0,他引:1
Claire Vallat-Azouvi Thomas Weber Ludovic Legrand Philippe Azouvi 《Journal of the International Neuropsychological Society》2007,13(5):770-780
The aim of the present study was to assess the functioning of the different subsystems of working memory after severe traumatic brain injury (TBI). A total of 30 patients with severe chronic TBI and 28 controls received a comprehensive assessment of working memory addressing the phonological loop (forward and backward digit span; word length and phonological similarity effects), the visuospatial sketchpad (forward and backward visual spans), and the central executive (tasks requiring simultaneous storage and processing of information, dual-task processing, working memory updating). Results showed that there were only marginal group differences regarding the functioning of the two slave systems, whereas patients with severe TBI performed significantly poorer than controls on most central executive tasks, particularly on those requiring a high level of controlled processing. These results suggest that severe TBI is associated with an impairment of executive aspects of working memory. The anatomic substrate of this impairment remains to be elucidated. It might be related to a defective activation of a distributed network, including the dorsolateral prefrontal cortex. 相似文献