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排序方式: 共有1070条查询结果,搜索用时 15 毫秒
31.
Head and neck squamous cell carcinoma lymphatic spread and survival: Relevance of vascular endothelial growth factor family for tumor evaluation 下载免费PDF全文
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Impact of Intraoperative Radiotherapy on Cosmetic Outcome and Complications after Oncoplastic Breast Surgery 下载免费PDF全文
Silvia Cracco MD Gloria Semprini MD Federico Cattin MD Giorgia Gregoraci MD Mark Zeppieri MD Miriam Isola MD Tino Ceschia MD Carla Cedolini MD Pier Camillo Parodi PhD 《The breast journal》2015,21(3):285-290
Breast cancer is one of the most common tumors in the population worldwide. Conservative breast surgery (CBS) is one of the preferred surgical options, because both the oncologic and esthetic needs of the patient can be addressed. CBS surgical outcomes tend to be more effective with reduced chances of disease recurrence when radiotherapy (RT) treatment is considered as an adjunct treatment, either applied during surgery (IORT) and/or after (EBRT). The purpose of our study was to compare surgical outcomes between IORT and EBRT after CBS. In the past 5 years, we performed CBS in 489 patients in our clinic. Of these patients, 83 underwent adjunct treatment with IORT and 109 were treated with EBRT in accordance with our university approved clinical protocol. Surgical outcomes, early complication rates, and esthetic results were compared between these two groups of CBS patients, with a mean follow‐up time of 17 months. IORT allowed breast irradiation treatment to be performed without effecting overlying skin, thus cosmetic outcomes tended to be favorable. Esthetic postoperative results assessed with the Breast Cancer Conservation Treatment (BCCTcore) software showed that the differences between IORT and EBRT were not statistically significant (including those patients that underwent further oncoplastic techniques after EBRT). The disease recurrence rates between the two groups were not significantly different. IORT is a safe, fast, and feasible technique that provides effective and comparable CBS outcomes for patients with breast cancer. 相似文献
33.
D'Annibale A Morpurgo E Fiscon V Trevisan P Sovernigo G Orsini C Guidolin D 《Diseases of the colon and rectum》2004,47(12):2162-2168
PURPOSE In the last ten years, several robotic systems have been developed to overcome the loss of the three-dimensional view and dexterity characteristic of laparoscopic surgery. The aim of this study was to compare the traditional laparoscopic approach and robotic techniques in the treatment of colorectal diseases.METHODS The study compares a consecutive series of patients treated surgically for colorectal disease from June 2001 to May 2003 with the da Vinci robotic system (Intuitive Surgical®) and a matched number of patients who underwent conventional laparoscopy during the same time interval. The factors analyzed were the time required to prepare the patient and the room, total time of surgery, length of specimens, number of lymph nodes retrieved, blood loss, complications, and postoperative results.RESULTS The study included 106 patients (53 in each group). No differences were observed in total time of surgery (laparoscopic group, 222 ± 77 minutes vs. robotic group, 240 ± 61 minutes), specimen length (laparoscopic group, 29 ± 11 cm vs. robotic group, 27 ± 13 cm), or number of lymph nodes retrieved (laparoscopic group, 16 ± 9 vs. robotic group, 17 ± 10). It took significantly longer to prepare the operating room and patient in the robotic group (24 ± 12 minutes) than in the laparoscopic group (18 ± 7 minutes). There were three conversions to laparotomy in the laparoscopic group; in the robotic group, two cases were converted to laparoscopy and three to hand-assisted laparoscopy. No significant differences were observed between the two groups in terms of recovery of bowel function and postoperative hospital stay.CONCLUSIONS Robot-assisted surgery proved to be as safe and effective as laparoscopic techniques in the treatment of colorectal diseases. Because of its dexterity and three-dimensional view, the da Vinci system was particularly useful in specific stages of the procedure, e.g., takedown of the splenic flexure, dissection of a narrow pelvis, identification of nervous plexus, and handsewn anastomosis. The cost-effectiveness of the procedure still needs to be evaluated. 相似文献
34.
Gianni Casella Pier Camillo Pavesi 《European heart journal》2003,24(22):2071; author reply 2071-2071; author reply 2072
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Paolo Spirito Camillo Autore Francesco Formisano Gabriele Egidy Assenza Elena Biagini Tammy S. Haas Sergio Bongioanni Christopher Semsarian Emmanuela Devoto Beatrice Musumeci Francesco Lai Laura Yeates Maria Rosa Conte Claudio Rapezzi Luca Boni Barry J. Maron 《The American journal of cardiology》2014
39.
Elena Biagini Iacopo Olivotto Maria Iascone Maria I. Parodi Francesca Girolami Giulia Frisso Camillo Autore Giuseppe Limongelli Massimiliano Cecconi Barry J. Maron Martin S. Maron Stefania Rosmini Francesco Formisano Beatrice Musumeci Franco Cecchi Attilio Iacovoni Tammy S. Haas Maria L. Bacchi Reggiani Paolo Ferrazzi Francesco Salvatore Paolo Spirito Claudio Rapezzi 《The American journal of cardiology》2014
40.
Gian Paolo Fadini MD Mario Luca Morieri MD Enrico Longato BE Benedetta Maria Bonora MD Silvia Pinelli MD Elisa Selmin MD Giacomo Voltan MD Daniele Falaguasta MD Silvia Tresso MD Giorgia Costantini MD Giovanni Sparacino PhD Barbara Di Camillo PhD Lara Tramontan PhD Anna Maria Cattelan MD Andrea Vianello MD Paola Fioretto MD Roberto Vettor MD Angelo Avogaro MD 《Diabetes, obesity & metabolism》2020,22(10):1946-1950
Because other coronaviruses enter the cells by binding to dipeptidyl-peptidase-4 (DPP-4), it has been speculated that DPP-4 inhibitors (DPP-4is) may exert an activity against severe acute respiratory syndrome coronavirus 2. In the absence of clinical trial results, we analysed epidemiological data to support or discard such a hypothesis. We retrieved information on exposure to DPP-4is among patients with type 2 diabetes (T2D) hospitalized for COVID-19 at an outbreak hospital in Italy. As a reference, we retrieved information on exposure to DPP-4is among matched patients with T2D in the same region. Of 403 hospitalized COVID-19 patients, 85 had T2D. The rate of exposure to DPP-4is was similar between T2D patients with COVID-19 (10.6%) and 14 857 matched patients in the region (8.8%), or 793 matched patients in the local outpatient clinic (15.4%), 8284 matched patients hospitalized for other reasons (8.5%), and when comparing 71 patients hospitalized for COVID-19 pneumonia (11.3%) with 351 matched patients with pneumonia of another aetiology (10.3%). T2D patients with COVID-19 who were on DPP-4is had a similar disease outcome as those who were not. In summary, we found no evidence that DPP-4is might affect hospitalization for COVID-19. 相似文献