全文获取类型
收费全文 | 1274篇 |
免费 | 63篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 23篇 |
妇产科学 | 52篇 |
基础医学 | 100篇 |
口腔科学 | 16篇 |
临床医学 | 199篇 |
内科学 | 92篇 |
皮肤病学 | 11篇 |
神经病学 | 116篇 |
特种医学 | 35篇 |
外科学 | 487篇 |
综合类 | 4篇 |
预防医学 | 108篇 |
眼科学 | 3篇 |
药学 | 41篇 |
中国医学 | 5篇 |
肿瘤学 | 38篇 |
出版年
2021年 | 17篇 |
2020年 | 7篇 |
2019年 | 13篇 |
2018年 | 19篇 |
2017年 | 14篇 |
2016年 | 14篇 |
2015年 | 10篇 |
2014年 | 29篇 |
2013年 | 28篇 |
2012年 | 65篇 |
2011年 | 75篇 |
2010年 | 39篇 |
2009年 | 25篇 |
2008年 | 88篇 |
2007年 | 91篇 |
2006年 | 78篇 |
2005年 | 77篇 |
2004年 | 61篇 |
2003年 | 47篇 |
2002年 | 57篇 |
2001年 | 43篇 |
2000年 | 45篇 |
1999年 | 33篇 |
1998年 | 11篇 |
1996年 | 7篇 |
1993年 | 8篇 |
1992年 | 10篇 |
1991年 | 12篇 |
1990年 | 15篇 |
1989年 | 18篇 |
1988年 | 24篇 |
1987年 | 15篇 |
1986年 | 18篇 |
1985年 | 19篇 |
1984年 | 17篇 |
1983年 | 7篇 |
1982年 | 9篇 |
1981年 | 12篇 |
1980年 | 14篇 |
1979年 | 18篇 |
1978年 | 19篇 |
1977年 | 12篇 |
1975年 | 6篇 |
1974年 | 8篇 |
1973年 | 9篇 |
1972年 | 14篇 |
1971年 | 8篇 |
1970年 | 6篇 |
1968年 | 11篇 |
1966年 | 7篇 |
排序方式: 共有1339条查询结果,搜索用时 10 毫秒
41.
Michael L. Cheatham Demetrios Demetriades Timothy C. Fabian Mark J. Kaplan William S. Miles Martin A. Schreiber John B. Holcomb Grant Bochicchio Babak Sarani Michael F. Rotondo 《World journal of surgery》2013,37(9):2018-2030
Background
The open abdomen has become a common procedure in the management of complex abdominal problems and has improved patient survival. The method of temporary abdominal closure (TAC) may play a role in patient outcome.Methods
A prospective, observational, open-label study was performed to evaluate two TAC techniques in surgical and trauma patients requiring open abdomen management: Barker’s vacuum-packing technique (BVPT) and the ABTheraTM open abdomen negative pressure therapy system (NPWT). Study endpoints were days to and rate of 30-day primary fascial closure (PFC) and 30-day all-cause mortality.Results
Altogether, 280 patients were enrolled from 20 study sites. Among them, 168 patients underwent at least 48 hours of consistent TAC therapy (111 NPWT, 57 BVPT). The two study groups were well matched demographically. Median days to PFC were 9 days for NPWT versus 12 days for BVPT (p = 0.12). The 30-day PFC rate was 69 % for NPWT and 51 % for BVPT (p = 0.03). The 30-day all-cause mortality was 14 % for NPWT and 30 % for BVPT (p = 0.01). Multivariate logistic regression analysis identified that patients treated with NPWT were significantly more likely to survive than the BVPT patients [odds ratio 3.17 (95 % confidence interval 1.22–8.26); p = 0.02] after controlling for age, severity of illness, and cumulative fluid administration.Conclusions
Active NPWT is associated with significantly higher 30-day PFC rates and lower 30-day all-cause mortality among patients who require an open abdomen for at least 48 h during treatment for critical illness. 相似文献42.
Bijan S. Kheirabadi Jennifer Sieber John B. Holcomb 《Journal of investigative surgery》2013,26(6):387-396
This study's objective was to investigate the potential thrombogenic effects of thrombin-containing fibrin sealant dressings (FSD) in a vascular repair model. Oval-shaped pieces of the rabbit abdominal aorta and vena cava were excised, the injuries were repaired with FSD, and animals were allowed to recover. Thrombus formation was examined by (1) an infusion of indium-labeled platelets into the rabbits following FSD application and estimation of total number of platelets attached to the wounds at 2, 4, and 6 h later (short-term effect, n = 12); and by (2) morphological and histological examinations of the vessels and dressings on days 1, 3, and 7 after repair operation in another group of rabbits (long-term effect, n = 12). Application of FSD sealed the vascular injures and produced immediate hemostasis that was stable up to 1 week. The highest numbers of platelets (both native and labeled) adhered to the arterial and venous repair sites were 6.5 × 106 and 4.4 × 107, respectively, 6 h after operation. The adhered platelets, however, did not form a visible and clinically significant thrombus. In long-term experiments, no evidence of thrombus was found in the lumens of the repaired vessels or on the dressings, and no microthrombi were detected histologically in other tissues at any time point. Although vena caval injuries showed signs of healing at day 7 postoperatively, the aortic wounds expanded progressively (pseudoaneurysm) and were prone to rupture at later times. Thus, direct exposure of FSD does not cause intravascular thrombosis or thrombotic events in rabbits. The dressing appears to be safe and effective for short-term repair of vascular injuries. It may also allow healing of minor venous defects, but cannot replace conventional surgical techniques (suturing) for permanent repair of arterial damages. 相似文献
43.
44.
45.
The role of semantics in the segmentation of morphologically complex words was examined using event-related potentials (ERPs) recorded to target words primed by semantically transparent (hunter-hunt,) opaque (corner-corn), and orthographically related (scandal-scan) masked primes. Behavioral data showed that only transparent items gave rise to priming. The ERP data showed both N250 and the N400 effects with transparent items generating greater priming than orthographic or opaque. Furthermore, priming effects across conditions revealed the existence of a significant linear trend, with transparent items showing the greatest effects and orthographic items the smallest, suggesting that these priming effects vary as a function of morphological structure and semantic transparency. The results are discussed in terms of a model of morphological processing. 相似文献
46.
47.
48.
49.
50.