全文获取类型
收费全文 | 8946篇 |
免费 | 579篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 55篇 |
儿科学 | 420篇 |
妇产科学 | 280篇 |
基础医学 | 903篇 |
口腔科学 | 39篇 |
临床医学 | 1540篇 |
内科学 | 1321篇 |
皮肤病学 | 158篇 |
神经病学 | 843篇 |
特种医学 | 202篇 |
外科学 | 831篇 |
综合类 | 71篇 |
一般理论 | 8篇 |
预防医学 | 1460篇 |
眼科学 | 80篇 |
药学 | 470篇 |
中国医学 | 3篇 |
肿瘤学 | 848篇 |
出版年
2024年 | 14篇 |
2023年 | 89篇 |
2022年 | 85篇 |
2021年 | 185篇 |
2020年 | 129篇 |
2019年 | 248篇 |
2018年 | 223篇 |
2017年 | 185篇 |
2016年 | 193篇 |
2015年 | 215篇 |
2014年 | 313篇 |
2013年 | 471篇 |
2012年 | 686篇 |
2011年 | 762篇 |
2010年 | 408篇 |
2009年 | 344篇 |
2008年 | 648篇 |
2007年 | 683篇 |
2006年 | 610篇 |
2005年 | 615篇 |
2004年 | 573篇 |
2003年 | 520篇 |
2002年 | 477篇 |
2001年 | 52篇 |
2000年 | 48篇 |
1999年 | 51篇 |
1998年 | 107篇 |
1997年 | 75篇 |
1996年 | 66篇 |
1995年 | 69篇 |
1994年 | 41篇 |
1993年 | 47篇 |
1992年 | 31篇 |
1991年 | 28篇 |
1990年 | 22篇 |
1989年 | 18篇 |
1988年 | 14篇 |
1987年 | 14篇 |
1986年 | 21篇 |
1985年 | 18篇 |
1984年 | 16篇 |
1983年 | 11篇 |
1982年 | 14篇 |
1981年 | 16篇 |
1980年 | 14篇 |
1979年 | 4篇 |
1978年 | 5篇 |
1977年 | 10篇 |
1973年 | 5篇 |
1972年 | 6篇 |
排序方式: 共有9532条查询结果,搜索用时 15 毫秒
61.
ATP sensitive (K(+)(ATP)) potassium cardiac channels are recruited when ATP levels are low as in ischemic injury and acute trauma. Such activation results in ECG-ST elevation and cardiac arrhythmias. K(+)(ATP) channel recruitment may be blocked by the sulfonylurea glibenclamide, permitting a wide variety of animal experimentation designed to test the genesis of ECG-ST segment elevations and depressions in diverse conditions including digitalis effect, acute arterial occlusion, tachycardias, and acute pericarditis. A specific series of animal experiments designed to test this hypothesis is proposed. Clinical implications are discussed. 相似文献
62.
Claes Lundsteen Beth Bjerregaard Erik Granum John Philip Kim Philip 《Clinical genetics》1980,17(3):183-190
63.
Muthotho JN Waiyaki PG Mbalu M Wairugu A Mwanthi B Odongo B 《African journal of health sciences》1995,2(1):232-235
Results of four years' studies from a number of hospitals in Kenya have shown that nosocomial infections in burns units are due to Methicillin Resistant Staphylococcus aureus (MRSA). Through chromosomal DNA and plasmid DNA, the stain is highly resistant to sulphonamide ointment and other antibiotics. 90% of patients admitted in burns units get colonized or infected with MRSA. The strain prolongs the duration of patients in hospitals. The burns degenerate to second and third degree burns, thereby necessitating skin grafting. The environment has been found to be contaminated with this strain with some staff members having chronic throat infections. Minocycline was found to be effective in treating the infected staff members. Cleaning this environment with Sodium dichloroisocyanurate (precepts)/Sodium hypochlorite (JIK) reduced drastically the mechanical transmission of bacteria in the units. The duration of stay of the patient was reduced. This shows that MRSA which is spread in government and private hospitals can cheaply be controlled by the proper use of disinfectants, antiseptics, and use of effective antibiotics when necessary. 相似文献
64.
Caudell TP Summers KL Holten J Hakamata T Mowafi M Jacobs J Lozanoff BK Lozanoff S Wilks D Keep MF Saiki S Alverson D 《Anatomical record. Part B, New anatomist》2003,270(1):23-29
Project TOUCH (Telehealth Outreach for Unified Community Health; http://hsc.unm.edu/touch) investigates the feasibility of using advanced technologies to enhance education in an innovative problem-based learning format currently being used in medical school curricula, applying specific clinical case models, and deploying to remote sites/workstations. The University of New Mexico's School of Medicine and the John A. Burns School of Medicine at the University of Hawai'i face similar health care challenges in providing and delivering services and training to remote and rural areas. Recognizing that health care needs are local and require local solutions, both states are committed to improving health care delivery to their unique populations by sharing information and experiences through emerging telehealth technologies by using high-performance computing and communications resources. The purpose of this study is to describe the deployment of a problem-based learning case distributed over the National Computational Science Alliance's Access Grid. Emphasis is placed on the underlying technical components of the TOUCH project, including the virtual reality development tool Flatland, the artificial intelligence-based simulation engine, the Access Grid, high-performance computing platforms, and the software that connects them all. In addition, educational and technical challenges for Project TOUCH are identified. 相似文献
65.
Beasley MB Franks TJ Galvin JR Gochuico B Travis WD 《Archives of pathology & laboratory medicine》2002,126(9):1064-1070
CONTEXT: The histologic patterns of diffuse alveolar damage (DAD), bronchiolitis obliterans with organizing pneumonia (BOOP), and eosinophilic pneumonia (EP) are well-recognized histologic patterns of lung injury associated with an acute or subacute clinical presentation. We have recognized acute fibrinous and organizing pneumonia (AFOP) as a histologic pattern, which also occurs in this clinical setting but does not meet the classic histologic criteria for DAD, BOOP, or EP and may represent an underreported variant. OBJECTIVE: To investigate the clinical significance of the AFOP histologic pattern and to explore its possible relationship to other disorders, including DAD and BOOP. DESIGN: Open lung biopsy specimens and autopsy specimens were selected from the consultation files of the Armed Forces Institute of Pathology, which showed a dominant histologic pattern of intra-alveolar fibrin and organizing pneumonia. Varying amounts of organizing pneumonia, type 2 pneumocyte hyperplasia, edema, acute and chronic inflammation, and interstitial widening were seen. Cases with histologic patterns of classic DAD, BOOP, abscess formation, or eosinophilic pneumonia were excluded. To determine the clinical behavior of patients with this histologic finding, clinical and radiographic information and follow-up information were obtained. Statistical analysis was performed using Kaplan-Meier and chi(2) analysis. RESULTS: Seventeen patients (10 men, 7 women) with a mean age of 62 years (range, 33-78 years) had acute-onset symptoms of dyspnea (11), fever (6), cough (3), and hemoptysis (2). Associations believed to be clinically related to the lung disease included definitive or probable collagen vascular disease (3), amiodarone (1), sputum culture positive for Haemophilus influenza (1), lung culture positive for Acinetobacter sp. (1), lymphoma (1), hairspray (1), construction work (1), coal mining (1), and zoological work (1). Six patients had no identifiable origin or association. Follow-up revealed 2 clinical patterns of disease progression: a fulminate illness with rapid progression to death (n = 9; mean survival, 0.1 year) and a more subacute illness, with recovery (n = 8). Histologic analysis and initial symptoms did not correlate with eventual outcome, but 5 of the 5 patients who required mechanical ventilation died (P =.007). CONCLUSIONS: Acute fibrinous and organizing pneumonia is a histologic pattern associated with a clinical picture of acute lung injury that differs from the classic histologic patterns of DAD, BOOP, or EP. Similar to these patterns of acute lung injury, the AFOP pattern can occur in an idiopathic setting or with a spectrum of clinical associations. The overall mortality rate is similar to DAD and therefore may represent a histologic variant; however, AFOP appears to have 2 distinct patterns of disease progression and outcome. The need for mechanical ventilation was the only parameter that correlated with prognosis. None of the patients with a subacute clinical course required mechanical ventilation. 相似文献
66.
Jiao Boshen Hankins Jane S. Devine Beth Barton Martha Bender M. Basu Anirban 《Quality of life research》2022,31(9):2729-2738
Quality of Life Research - There is a paucity of empirically estimated health state utility (HSU) values to estimate health-related quality of life among individuals with sickle cell disease (SCD).... 相似文献
67.
Howard Mary Beth Jarvis Lenore R. Badolato Gia M. Parrish Benjamin T. Donnelly Katie A. 《Maternal and child health journal》2022,26(5):1059-1066
Maternal and Child Health Journal - Sleep-related infant deaths in the District of Columbia (DC) varies, with rates in certain geographical areas three times higher than DC and seven times higher... 相似文献
68.
69.
70.