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101.
Pietro Buzzini Benedetta Turchetti Eva Branda Marta Goretti Marco Amici Paul Emile Lagneau Licia Scaccabarozzi Valerio Bronzo Paolo Moroni 《Medical mycology》2008,46(5):511-514
A large scale screening of the in vitro susceptibility of 105 strains of Prototheca zopfii to a panel of polyene antibiotics (amphotericin B, nystatin, primaricin and filipin) was conducted. Strains studied were isolated from dairy-associated environments in five different localities. Groups 1-4 included strains recovered from four separate regions of Italy, while group 5 included isolates from Belgium. Amphotericin B and primaricin exhibited the highest activity, with th MIC90 ranging from 4 and 8 microg/ml, respectively. On the other hand, the MIC90 of nystatin and filipin were from two to four times higher. Two strains were resistant to all four polyenes tested. The above results are compared with those in the literature and the importance of carrying out large-scale screening surveys to assess polyene susceptibility patterns within the species P. zopfii is discussed. 相似文献
102.
The relation between mean aortic pressure (mAoP) and the duration of cardiac cycle (C) has been studied in resting conscious dogs in normal condition (n), after vagal blockade (vb), after sympathetic blockade (sb), and after combined blockade of the two systems (sb+vb). The relation has been found to be negative in all conditions. The different conditions are clearly differentiated by the slope of the relation between mAoP/C (= kPa/s = mW/ml) and C. The hypothesis is put forward that the balance between sympathetic and parasympathetic activities on the heart and the vessels produces the best compromise between the pump function of the heart and the afterload, in relation to the actual behavioural situation, in conscious animals. 相似文献
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106.
Giovanni Mistraletti Michele Umbrello Elena Silvia Mantovani Benedetta Moroni Paolo Formenti Paolo Spanu Stefania Anania Elisa Andrighi Alessandra Di Carlo Federica Martinetti Irene Vecchi Alessandra Palo Cristina Pinna Riccarda Russo Silvia Francesconi Federico Valdambrini Enrica Ferretti Giulio Radeschi Edda Bosco Paolo Malacarne Gaetano Iapichino The http://www.intensiva.it Investigators 《Intensive care medicine》2017,43(1):69-79
Purpose
Good communication between ICU staff and patients’ relatives may reduce the occurrence of post-traumatic stress disorder, anxiety or depression, and dissatisfaction with clinicians. An information brochure and website to meet relatives’ needs were designed to explain in technical yet simple terms what happens during and after an ICU stay, to legitimize emotions such as fear, apprehension, and suffering, and to improve cooperation with relatives without increasing staff workload. The main outcomes were improved understanding of prognosis and procedures, and decrease of relatives’ anxiety, depression, and stress symptoms.Methods
In this prospective multicenter before-and-after study, a self-administered questionnaire was used to investigate relatives’ understanding of prognosis, treatments, and organ dysfunction, families’ satisfaction, and symptoms of anxiety, depression, and post-traumatic stress.Results
A total of 551 relatives received questionnaires in nine Italian ICUs; 332 (60%) responded, 144 before and 179 after implementation of the brochure and website. Of the 179 relatives who responded after, 131 (73%) stated they had read the brochure and 34 (19%) reported viewing the website. The intervention was associated with increased correct understanding of the prognosis (from 69 to 84%, p = 0.04) and the therapeutic procedures (from 17 to 28%, p = 0.03). Multivariable analysis, together with non-modifiable factors (relative’s gender, education level, relationship to patient, and patient status at ICU discharge), showed the intervention to be significantly associated with a lower incidence of post-traumatic stress symptoms (Poisson coefficient = ?0.29, 95% CI ?0.52/?0.07). The intervention had no effect on the prevalence of symptoms of anxiety and depression.Conclusion
An information brochure and website designed to meet relatives’ needs improved family members’ comprehension and reduced their prevalence of stress symptoms.107.
Glomb Katharina Cabral Joana Cattani Anna Mazzoni Alberto Raj Ashish Franceschiello Benedetta 《Brain topography》2022,35(1):142-161
Brain Topography - Computational models lie at the intersection of basic neuroscience and healthcare applications because they allow researchers to test hypotheses in silico and predict the outcome... 相似文献
108.
Billings Jacob Tivadar Ruxandra Murray Micah M. Franceschiello Benedetta Petri Giovanni 《Brain topography》2022,35(1):79-95
Brain Topography - Electroencephalography (EEG) is among the most widely diffused, inexpensive, and adopted neuroimaging techniques. Nonetheless, EEG requires measurements against a reference... 相似文献
109.
Russo CR Lauretani F Bandinelli S Bartali B Cavazzini C Guralnik JM Ferrucci L 《Archives of physical medicine and rehabilitation》2003,84(12):1854-1857
OBJECTIVE: To test whether training on a high-frequency (28Hz) vibrating platform improves muscle power and bone characteristics in postmenopausal women. DESIGN: Randomized controlled trial with 6-month follow-up. SETTING: Outpatient clinic in a general hospital in Italy. PARTICIPANTS: Twenty-nine postmenopausal women (intervention group, n=14; matched controls, n=15). INTERVENTION: Participants stood on a ground-based oscillating platform for three 2-minute sessions for a total of 6 minutes per training session, twice weekly for 6 months. The controls did not receive any training. Both groups were evaluated at baseline and after 6 months. MAIN OUTCOME MEASURES: Muscle power, calculated from ground reaction forces produced by landing after jumping as high as possible on a forceplate, cortical bone density, and biomarkers of bone turnover. RESULTS: Over 6 months, muscle power improved by about 5% in women who received the intervention, and it remained unchanged in controls (P=.004). Muscle force remained stable in both the intervention and control groups. No significant changes were observed in bone characteristics. CONCLUSION: Reflex muscular contractions induced by vibration training improve muscle power in postmenopausal women. 相似文献
110.
Symptomatic and presumed symptomatic focal epilepsies in childhood: An observational,prospective multicentre study 下载免费PDF全文
Marilena Vecchi Carmen Barba Debora De Carlo Micol Stivala Renzo Guerrini Emilio Albamonte Domiziana Ranalli Domenica Battaglia Giada Lunardi Clementina Boniver Benedetta Piccolo Francesco Pisani Gaetano Cantalupo Giuliana Nieddu Susanna Casellato Silvia Cappanera Elisabetta Cesaroni Nelia Zamponi Domenico Serino Lucia Fusco Alessandro Iodice Filippo Palestra Lucio Giordano Elena Freri Ilaria De Giorgi Francesca Ragona Tiziana Granata Isabella Fiocchi Stefania Maria Bova Massimo Mastrangelo Alberto Verrotti Sara Matricardi Elena Fontana Davide Caputo Francesca Darra Bernardo Dalla Bernardina Francesca Beccaria Giuseppe Capovilla Maria Pia Baglietto Alessandra Gagliardi Aglaia Vignoli Maria Paola Canevini Egle Perissinotto Stefano Francione 《Epilepsia》2016,57(11):1808-1816