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101.
Erkan Alpsoy Mualla Polat Ibrahim Halil Yavuz Pelin Kartal Didem Didar Balci Ayse Serap Karadag Asli Bilgic Ercan Arca Bilge Fettahlioglu Karaman Selma Emre Esra Adisen Neslihan Sendur Ozlem Bilgic Ayca Cordan Yazici Basak Yalcin Rafet Koca Kamer Gunduz Murat Borlu Tulin Ergun Pinar Dursun Serap Gunes Bilgili Asli Surer Adanir Ayla Gulekon Gizem Yagcioglu Ertan Yilmaz Ufuk Kavuzlu Yesim Senol 《ANNALS OF DERMATOLOGY》2020,32(3):181
BackgroundInternalized stigma, adoption of negative attitudes and stereotypes of the society regarding persons'' illness, has not been studied previously in pediatric psoriasis patients.ObjectiveWe aimed to investigate the internalized stigma in pediatric psoriasis patients and to determine differences according to factors affecting internalized stigma compared to adult psoriasis patients.MethodsThis multicenter, cross-sectional, comparative study included 125 pediatric (55 female, 70 male; mean age±standard deviation [SD], 14.59±2.87 years) and 1,235 adult psoriasis patients (577 female, 658 male; mean age±SD, 43.3±13.7 years). Psoriasis Internalized Stigma Scale (PISS), Dermatology Life Quality Index (DLQI), Perceived Health Status (PHS), and the General Health Questionnaire (GHQ)-12 were the scales used in the study.ResultsThe mean PISS was 58.48±14.9 in pediatric group. When PISS subscales of groups were compared, the pediatric group had significantly higher stigma resistance (p=0.01) whereas adult group had higher scores of alienation (p=0.01) and stereotype endorsement (p=0.04). There was a strong correlation between mean values of PISS and DLQI (r=0.423, p=0.001). High internalized stigma scores had no relation to either the severity or localization of disease in pediatric group. However, poor PHS (p=0.007) and low-income levels (p=0.03) in both groups, and body mass index (r=0.181, p=0.04) in the pediatric group were related to high PISS scores.ConclusionInternalized stigma in pediatric patients is as high as adults and is related to poor quality of life, general health, and psychological illnesses. Unlike adults, internalized stigma was mainly determined by psoriasis per se, rather than disease severity or involvement of visible body parts, genitalia or folds. 相似文献
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Emre A Ucer E Yesilcimen K Bilsel T Oz D Sayar N Terzi S Akbulut T Ersek B 《Cardiology》2006,106(4):264-269
BACKGROUND/AIMS: The timing of GpIIb/IIIa inhibitor administration may be important in achieving early epicardial and myocardial reperfusion. We evaluated the effect of early tirofiban on myocardial salvage and cardiovascular outcome in patients with acute myocardial infarction (AMI) undergoing infarct-related artery stenting. METHODS: Patients (n = 66) with a first AMI presenting <6 h from onset of symptoms were randomized to either early administration of tirofiban in the emergency room (n = 32) or later administration in the catheterization laboratory (n = 34) (tirofiban bolus dose of 10 microg/kg, followed by 0.15 microg/kg for 24 h). The primary end-point was the degree of myocardial salvage, determined by means of serial scintigraphic studies with technetium-99m sestamibi. Thirty-day major adverse cardiac events were also assessed. RESULTS: There were no significant differences in patient characteristics or in their presentation. The mean door-to-balloon time was similar in both groups (43 +/- 12 and 53 +/- 9 min, p = 0.08). The early and late treatment groups received tirofiban 18 +/- 4 and 52 +/- 10 min after admission, respectively. Angiographic analysis revealed a higher initial frequency of TIMI grade 3 flow in the early group (31% vs. 12%, p = 0.04). Procedural success was achieved in all patients. Myocardial risk area were comparable between early and late treatment groups (35.6 +/- 12.2% vs. 39.3 +/- 14.0%, p = 0.6). Scintigraphic outcomes demonstrated a significant reduction in the final infarction size (11.8 +/- 5.2% vs. 22.4 +/- 6.2%, p = 0.01), and improvement in salvage index (0.68 +/- 0.22 vs. 0.44 +/- 0.18, p = 0.003) in favor of the early tirofiban group. The thirty-day composite end-point of death, recurrent MI or rehospitalization also favored the early group (6% early, 15% late, p = 0.06). CONCLUSION: Early tirofiban administration enhanced the degree of myocardial salvage and clinical outcome in patients with AMI undergoing infarct-related artery stenting. 相似文献
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Kadir Desdicioglu Mehmet Ali Malas Selen Bahceci Fatma Simsek Ayse Gizem Polat 《Journal of the Anatomical Society of India》2017,66(1):37-42
Introduction
In our study, the aim was to anatomically and histologically investigate the morphometric structures of the branches involved in the sural nerve and sural nerve formation.Method
The study was conducted on 46 lower extremities of 23 fetuses which were obtained from Izmir Katip Çelebi University, Atatürk Training and Research Hospital, with ages from 18 and 32 gestational weeks, without any external pathology or anomaly. During the study period, the posterior-side skin dissection of the lower extremity was performed with the aid of a surgical dissection microscope initially, and the structures forming the sural nerve and the sural nerve were exposed and made visible. Afterwards, sections were taken from these structures for morphometric measurements and histological examination.Results
The mean values and standard deviations of morphometric measurements obtained were determined. Separately, it was determined that there was no statistical difference between right-left sides and genders in morphometric measurements (p > 0.05). The sural nerve was determined to be differentiated into 4 types as A, B, C and D according to the way the nerve branches forming sural nerve join. In addition, differing characteristics pertaining to the sural nerve and branches were determined.Discussion
We are of the opinion that the data obtained in our study will be of use to neurologists, orthopedists and clinicians engaged in this region during interventional procedures. 相似文献107.
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Ayse Tosun Gul Serdaroglu Muzaffer Polat Hasan Tekgul Sarenur Gokben 《Indian journal of pediatrics》2009,76(5):547-550
Objective We aimed to describe the epidemiologic, clinical, laboratory features, neuroimaging, treatment, and outcome of children with
acute disseminated encephalomyelitis in a cohort study.
Methods In this study, twelve children who were diagnosed as acute disseminated encephalomyelitis were reviewed retrospectively. All
of the cases were reevaluated with systemic and neurological examinations, serologic tests, cerebrospinal fluid investigations,
magnetic resonance imaging.
Result Their age ranged between 2.5 and 16 years. Five of the cases had initial infections. Patients presented most often with motor
deficits (75%), secondly with loss of conscious (33%), and seizures (33%). Spinal fluid abnormalities occurred in 41.6%. Cranial,
and spinal magnetic resonance imaging (MRI) revealed hyperintense signal changes mainly in basal ganglia and thalamus (58%),
cortical and subcortical areas (33) in T2 weighted images. Myelitis was determined in two cases. Six patients were treated
with steroid, and 3 were treated with intravenous immunoglobulin. Ten patients recovered completely. We observed relapse in
one case and recurrence in two cases. These cases responded well to high dose intravenous prednisolone followed by oral prednisolone
for 6 months.
Conclusion Outlook recovery is generally good in acute disseminated encephalomyelitis. Recurrence and neurological deficits are rarely
seen. Early treatment of prednisolone is one of the most important factors to determine the prognosis in this disease. 相似文献
110.
Fatih Kose Ayberk Besen Saime Paydas Mustafa Balal Gulfiliz Gonlusen Tamer Inal Ayse Dogan Mustafa Kibar 《Clinical and experimental nephrology》2010,14(1):22-27