全文获取类型
收费全文 | 2949篇 |
免费 | 126篇 |
国内免费 | 35篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 81篇 |
妇产科学 | 66篇 |
基础医学 | 236篇 |
口腔科学 | 63篇 |
临床医学 | 204篇 |
内科学 | 934篇 |
皮肤病学 | 35篇 |
神经病学 | 213篇 |
特种医学 | 125篇 |
外科学 | 562篇 |
综合类 | 14篇 |
一般理论 | 1篇 |
预防医学 | 112篇 |
眼科学 | 37篇 |
药学 | 140篇 |
肿瘤学 | 270篇 |
出版年
2024年 | 2篇 |
2023年 | 34篇 |
2022年 | 41篇 |
2021年 | 72篇 |
2020年 | 37篇 |
2019年 | 67篇 |
2018年 | 77篇 |
2017年 | 72篇 |
2016年 | 58篇 |
2015年 | 69篇 |
2014年 | 110篇 |
2013年 | 158篇 |
2012年 | 255篇 |
2011年 | 255篇 |
2010年 | 169篇 |
2009年 | 160篇 |
2008年 | 252篇 |
2007年 | 255篇 |
2006年 | 237篇 |
2005年 | 202篇 |
2004年 | 173篇 |
2003年 | 131篇 |
2002年 | 107篇 |
2001年 | 9篇 |
2000年 | 9篇 |
1999年 | 12篇 |
1998年 | 12篇 |
1997年 | 14篇 |
1996年 | 11篇 |
1995年 | 8篇 |
1994年 | 5篇 |
1993年 | 3篇 |
1992年 | 7篇 |
1991年 | 4篇 |
1990年 | 3篇 |
1989年 | 1篇 |
1986年 | 1篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1978年 | 2篇 |
1976年 | 2篇 |
1975年 | 3篇 |
1969年 | 1篇 |
1963年 | 1篇 |
1962年 | 1篇 |
1960年 | 1篇 |
排序方式: 共有3110条查询结果,搜索用时 15 毫秒
101.
Tranos Paris G. Allan Bruce Balidis Miltiadis Vakalis Athanasios Asteriades Solon Anogeianakis George Triantafilla Magda Kozeis Nikolaos Stavrakas Panagiotis 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2020,258(5):987-993
Graefe's Archive for Clinical and Experimental Ophthalmology - To investigate the accuracy of preoperative biometry in eyes undergoing combined phacovitrectomy and to compare it with eyes... 相似文献
102.
Panagiotis Lepetsos Andreas Pampanos Emmanouil Kanavakis Maria Tzetis Dimitrios Korres Athanasios G. Papavassiliou Nicolaos Efstathopoulos 《Journal of orthopaedic research》2014,32(9):1155-1160
103.
104.
105.
106.
Sexual dysfunction is currently considered a serious quality-of-life-related health problem, exerting a major impact on patients' and their sexual partners' life. Available data indicate that essential hypertension is a risk factor for sexual dysfunction, as male and female sexual dysfunction is more prevalent in hypertensive patients than normotensive individuals. Several mechanisms have been implicated in the pathogenesis of sexual dysfunction in hypertensive patients, and major determinants include severity and duration of hypertension, age, and antihypertensive therapy. Female sexual dysfunction, although more frequent than its male counterpart, remains largely under-recognized. Older antihypertensive drugs (diuretics, beta-blockers, centrally acting) exert negative results, whereas newer drugs have either neutral (calcium antagonists, angiotensin-converting enzyme inhibitors) or beneficial effects (angiotensin receptor blockers). Erectile dysfunction is related to ischemic heart disease and might be an 'early therapeutic window' of asymptomatic coronary artery disease. It seems of utmost importance for every physician treating hypertensive patients to become familiar with sexual dysfunction (through better education and specific seminars) for the proper management of these patients. 相似文献
107.
Shaughnessy J Jacobson J Sawyer J McCoy J Fassas A Zhan F Bumm K Epstein J Anaissie E Jagannath S Vesole D Siegel D Desikan R Munshi N Badros A Tian E Zangari M Tricot G Crowley J Barlogie B 《Blood》2003,101(10):3849-3856
Metaphase cytogenetic abnormalities (CAs), especially of chromosome 13 (CA 13), confer a grave prognosis in multiple myeloma even with tandem autotransplantations as applied in Total Therapy I, which enrolled 231 patients between 1989 and 1994. With a median follow-up of almost 9 years, the prognostic implications of all individual CAs, detected prior to treatment and at relapse, were investigated. Among all CAs and standard prognostic factors examined prior to therapy, only hypodiploidy and CA 13 (hypo-13 CA), alone or in combination, were associated with shortest event-free survival and overall survival (OS). The shortest postrelapse OS was observed with hypo-13 CA, which was newly detected in 18 of all 28 patients presenting with this abnormality at relapse. Superior prognosis was associated with the absence of any CA at both diagnosis and relapse (10-year OS, 40%). The lack of independent prognostic implications of other CAs points to a uniquely aggressive behavior of hypo-13 CA (present in 16% of patients at diagnosis). With the use of microarray data in 146 patients enrolled in Total Therapy II, overexpression of cell cycle genes distinguished CA from no CA, especially in cases of del(13) detected by interphase fluorescence in situ hybridization (FISH). FISH 13, resulting in a haploinsufficiency of RB1 and other genes mapping to chromosome 13, as well as activation of IGF1R, appears to have an amplifying effect on cell cycle gene expression, thus providing a molecular explanation for the dire outcome of patients with CA 13 compared with those with other CAs. 相似文献
108.
109.
Dimitrios Dimitroulis Dimitrios Patsouras Athanasios Katsargyris Petros Charalampoudis Ioannis Anastasiou Gregory Kouraklis 《International surgery》2014,99(5):669-672
Primary carcinoma of the male urethra accounts for less than 1% of malignancies in men. Mucinous adenocarcinoma of the urethra is extremely rare, and its biologic behavior is poorly understood. We present herein a rare case of mucinous urethral adenocarcinoma in a male patient with longstanding ulcerative colitis and multiple sclerosis. The patient presented with a voluminous pelvic mass; core biopsy of the lesion demonstrated a mucus-producing adenocarcinoma. Given the patient''s history of subtotal colectomy, preoperative diagnosis was oriented towards a rectal stump adenocarcinoma. The patient underwent a pelvic exenteration: surprisingly, histology marked the prostatic urethra as the primary lesion site.Key words: Urethra, Adenocarcinoma, Mucinous, Ulcerative colitisPrimary enteric-type mucinous adenocarcinoma of the urethra is an extremely rare entity with aggressive clinical course regardless of treatment. Interestingly, it has been implied that inflammatory bowel disease and multiple sclerosis share common mechanisms of impaired histocompatibility. Moreover, patients with inflammatory bower disease who receive prolonged immunosuppression such as azathioprine tend to increasingly develop urinary tract malignancies. We report herein a complex case of enteric-type mucinous adenocarcinoma of urethral origin in a male with a longstanding history of ulcerative colitis and multiple sclerosis. 相似文献
110.
Minas Baltatzis Theodoros E. Pavlidis Odysseas Ouroumidis Georgios Koliakos Christina Nikolaidou Ioannis Venizelos Anna Michopoulou Athanasios Sakantamis 《The Journal of surgical research》2014