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51.
Indian Journal of Pediatrics - 相似文献
52.
A rare case of splenic abscess occurring after blunt abdominal trauma in a previously healthy boy is reported. The diagnosis
was made by ultrasonography. The patient recovered after splenectomy and drainage of subphrenic and intraperitoneal pus. 相似文献
53.
A comprehensive survey was carried out to asses the Vitamin A status of pre-school (0–6 yrs.) and school age (6–12 yrs.) children
of socio-economically backward families from slums of Bombay and its suburbs. The Vitamin A, protein, calories and iron from
the rice and dal based diet was found to be below recommended dietary allowances (RDA). Among the 1956 children surveyed 20%
of the children showed low (<20 μg/dl) serum vitamin A levels. 4.8% of the children were suffering from one or the other signs
of Vitamin A deficiency. Rose Bengal stain test (RBST) and conjuctival impression cytology (CIC) indicted the signs of mild
conjuctival xerosis and of early epithelial changes which were correlated with serum vitamin A levels. Serum iron, PCV, Hb
and RBC levels were below normal. The anthropometric measurements of these children were below 50th percentile of Indian Council
of Medical Research (ICMR) standards. Due to lack of proper nutrition, the overall growth of children is either retarded or
not upto the standard levels as was noted in majority of the children. 相似文献
54.
Bhardwaj N Kukade JA Patil S Bhardwaj S 《Indian journal of maternal and child health : official publication of Indian Maternal and Child Health Association,》1995,6(2):33-39
In 1992 at Vivekanand Hospital in Latur, Maharashtra State, India, researchers randomly allocated 326 pregnant women, 15-45 years old, at full term, to either the modified squatting position group (study group) or the normal lithotomy delivery position group (control group) to determine whether the modified squatting position using a birth cushion has any advantages over the normal delivery position. The U-shaped cushion is inexpensive, constructed with coir and foam, and has a washable cover. Its two handles provide the woman support as she pushes and delivers the newborn. There were 145 women in the study group and 181 in the control group. Women in the squatting position did not receive any episiotomies. They spent less time pushing (i.e., in second stage of labor) than those in the control group (median, 21.2 vs. 39.32 min; p 0.01), especially among gravidae 2 and above. The time required to perform vaginal operative delivery was much shorter for the squatting position than for the normal delivery position (11.6 vs. 28.86 min; p 0.01). Fetal stress was more common among newborns delivered by the normal delivery position than among those delivered by the squatting position (7.73% vs. 3.44%; p 0.05). Women in the squatting group were more likely to have an intact perineum after delivery than those in the control group. None of the women in the control group had postpartum vulval edema, while five in the study group did. The edema was mild, however, and resolved itself within 24 hours of delivery. Most women in the squatting position group were satisfied with this position. These findings suggest that the squatting position using a birth cushion has more benefits than the normal delivery position. It allows better coordination and more effective pushing. Traditional birth attendants and female health workers at subcenter and primary health center levels can be trained to use the birth cushion during labor. 相似文献
55.
Antigen binding characteristics of experimentally-induced antibodies against hydroxyl radical modified native DNA 总被引:3,自引:0,他引:3
Hydroxyl radical, generated by UV irradiation of hydrogen peroxide caused damage to native calf thymus DNA leading to strand breaks, base modification and decrease in melting temperature. The ROS-DNA was highly immunogenic in goat. The antibody activity was inhibited to the extent of 89% with the immunogen as inhibitor. Antigenic specificity of anti-ROS-DNA antibodies by competition ELISA showed multiple cross-reactivity, recognizing B-, A- and allied conformations. The immune complex formation with native and ROS-DNA was substantiated by band shift assay. A striking observation, is the enhanced recognition of ROS-thymine and ROS-poly(dT) by the induced antibodies. These investigations suggest that ROS might be the plausible candidate for the presentation of unique epitopes on ROS-DNA, in particular of thymine, inducing antibodies cross-reacting with native DNA and play an important role in the pathogenesis of SLE. 相似文献
56.
Klinge U Zheng H Si Z Schumpelick V Bhardwaj RS Muys L Klosterhalfen B 《European surgical research. Europ?ische chirurgische Forschung. Recherches chirurgicales européennes》1999,31(6):480-490
Although abnormal collagen metabolism has been ascribed an important role in the high recurrence rates after surgical hernia repair, knowledge on tissue sampled in the region affected by inguinal hernias is poor. In the present study, we determined collagen type I and type III in the skin of adult patients with indirect and direct inguinal hernias by both immunohistochemistry and Western blot analysis. In addition, we quantified the immunohistochemical expression of fibronectin and matrix metalloproteinase (MMP)-1 and -13. The results indicated that the ratio of collagen type I/III was significantly decreased in the skin of patients with either indirect (n = 9) or direct hernia (n = 7), with a concomitant increase in collagen type III (p < 0.001 vs. controls, n = 7, without affection of the inguinal region). There was no significant difference between patients with indirect and direct hernia (p > 0.05). MMP-13 was not expressed in any of the skin samples investigated, whereas MMP-1 was found in the epidermis. Fibronectin was predominantly detected at the epidermal-dermal junction. MMP-1, MMP-13 and fibronectin levels were significantly different between patients and controls (p > 0. 05). We conclude that in contrast to the unchanged expression of fibronectin and MMP-1 and MMP-13, the decreased ratios of collagen tpye I/III with the basically increased amount of collagen type III could be of significant importance for the pathophysiology of hernias. The specific ratio collagen I/III probably reflects the altered structural integrity and mechanical stability of the connective tissue in both indirect and direct hernias. Moreover, our findings stress that hernias should be regarded as the manifestation of a systemic disease in the inguinal region with a genetic background, explaining the high recurrence rates after repeated suture repair, as well as the usefulness of surgical meshes in this clinical setting. 相似文献
57.
Klinge U Zheng H Si ZY Schumpelick V Bhardwaj R Klosterhalfen B 《International journal of surgical investigation》1999,1(3):219-227
Since many years the importance of a weakness of the soft tissue for the development of hernias is discussed controversially. The tensile strength of the tissue is supposed to depend largely on the varying proportion of type I collagen with its high tensile strength and the immature type III collagen. Their relation is regulated by several collagenases, mainly matrix metalloproteinases-1 and -13 (MMP-1 and MMP-13), whereas fibronectin plays a key role for the adherence of cells within the extracellular matrix. The aim of this study was to investigate whether an alteration in type I and type III collagen synthesis, amounts of MMP-1 and MMP-13 and the expression of fibronectin were associated with the development of inguinal hernia. We analysed the hernial sac of patients with indirect (n = 9) and direct (n = 7) inguinal hernias and peritoneum in controls (n = 7) by immunohistochemistry and Western blot analysis. The results showed that the ratio of relative amount of I/III collagen was markedly decreased in patients with either indirect or direct hernias as compared with controls (p < 0.001) with a concomitant increase in type III collagen synthesis. MMP-13 was expressed neither in the hernial sac nor in the peritoneum of the controls, but the positive reactions of MMP-1 were found in the surface of the subserosa of the hernial sac in patients with indirect or direct hernias without any difference compared to controls. Furthermore, the relative amount of fibronectin in patients with either indirect or direct hernias is not significantly different from controls (p > 0.05). In regard to the known alterations of the collagen metabolism in fascia and skin of hernia patients the changed collagen I/III ratio with its increase of type III collagen in hernial sacs support the presence of a systemic disturbance of collagen metabolism. The absence of changes of the expression of collagenases (MMP-1, MMP-13) and the constant levels of fibronectin underline the central role of collagen synthesis for the development of indirect or direct hernias. 相似文献
58.
59.
Purpose
We determined if separation of spermatozoa (washed) on a discontinuous colloidal suspension of silica (Percoll†) density gradient before cryopreservation improves post-thaw motility compared to an unprocessed (raw) cryopreserved sample.Materials and Methods
Ten normal healthy volunteers recruited into the andrology laboratory donor program were studied. Raw and washed cryopreserved spermatozoa were compared for loss of motility with time, motion characteristics, viability and membrane integrity after incubation for 1, 6 and 24 hours. Within group comparisons were made to baseline measurements (0 hours before incubation).Results
Raw and washed cryopreserved spermatozoa showed statistically significant decreases in motility and other motion characteristics after thawing. There were significant decreases in motility and other motion characteristics after incubation periods of 1, 6 and 24 hours, and significant decreases in viability and membrane integrity at 6 and 24 hours in the unprocessed spermatozoa. Although, motility and motion characteristics of washed samples decreased significantly with longer incubation periods, loss of motility with time (longevity) was greater in raw samples. Washed samples retained greater sperm motility for up to 24 hours (p less than 0.03).Conclusions
Specimens prepared by Percoll separation techniques before freezing offer the possibility of selecting spermatozoa that retain motility for up to 24 hours. This finding can be of benefit for couples undergoing intrauterine insemination to achieve pregnancy. 相似文献60.
Ashok N. Kukadia Cesar J. Ercole Paul Gleich Hugh Hensleigh Jon L. Pryor 《The Journal of urology》1996,156(5):1643-1646