全文获取类型
收费全文 | 10249篇 |
免费 | 736篇 |
国内免费 | 37篇 |
专业分类
耳鼻咽喉 | 77篇 |
儿科学 | 293篇 |
妇产科学 | 293篇 |
基础医学 | 1380篇 |
口腔科学 | 233篇 |
临床医学 | 1274篇 |
内科学 | 2036篇 |
皮肤病学 | 259篇 |
神经病学 | 1082篇 |
特种医学 | 184篇 |
外科学 | 893篇 |
综合类 | 64篇 |
一般理论 | 16篇 |
预防医学 | 1306篇 |
眼科学 | 181篇 |
药学 | 682篇 |
中国医学 | 32篇 |
肿瘤学 | 737篇 |
出版年
2024年 | 16篇 |
2023年 | 132篇 |
2022年 | 225篇 |
2021年 | 462篇 |
2020年 | 263篇 |
2019年 | 359篇 |
2018年 | 375篇 |
2017年 | 273篇 |
2016年 | 315篇 |
2015年 | 316篇 |
2014年 | 393篇 |
2013年 | 579篇 |
2012年 | 830篇 |
2011年 | 821篇 |
2010年 | 472篇 |
2009年 | 372篇 |
2008年 | 632篇 |
2007年 | 620篇 |
2006年 | 569篇 |
2005年 | 540篇 |
2004年 | 455篇 |
2003年 | 438篇 |
2002年 | 389篇 |
2001年 | 42篇 |
2000年 | 34篇 |
1999年 | 39篇 |
1998年 | 68篇 |
1997年 | 68篇 |
1996年 | 60篇 |
1995年 | 51篇 |
1994年 | 40篇 |
1993年 | 45篇 |
1992年 | 32篇 |
1991年 | 31篇 |
1990年 | 26篇 |
1989年 | 24篇 |
1988年 | 27篇 |
1987年 | 28篇 |
1986年 | 25篇 |
1985年 | 26篇 |
1984年 | 33篇 |
1983年 | 39篇 |
1982年 | 35篇 |
1981年 | 35篇 |
1980年 | 41篇 |
1979年 | 13篇 |
1978年 | 17篇 |
1977年 | 18篇 |
1975年 | 14篇 |
1973年 | 15篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
21.
22.
We have previously demonstrated that p100H mutant mice, which lack a functional Sox6 gene, exhibit skeletal and cardiac muscle degeneration and develop cardiac conduction abnormalities soon after birth. To understand the role of Sox6 in skeletal muscle development, we identified muscle-specific genes differentially expressed between wild-type and p100H mutant skeletal muscles and investigated their temporal expression in the mutant muscle. We found that, in the mutant skeletal muscle, slow fiber and cardiac isoform genes are expressed at significantly higher levels, whereas fast fiber isoform genes are expressed at significantly lower levels than wild-type. Onset of this aberrant fiber type-specific gene expression in the mutant coincides with the beginning of the secondary myotube formation, at embryonic day 15-16 in mice. Together with our earlier report, demonstrating early postnatal muscle defects in the Sox6 null-p100H mutant, the present results suggest that Sox6 likely plays an important role in muscle development. 相似文献
23.
The isthmo-optic nuclei (ION) and ectopic neurons, which constitute the centrifugal visual system (CVS), are thought to be cholinoceptive and nitrergic. However, it is not clear which neurons express these markers, namely the ones that project to the retina rather than in neurons that only participate in a local circuit. Therefore, to characterize the neurochemical patterns of the centrifugal visual system in the post-hatched chick, retinopetal cells of the isthmo-optic nuclei and the ectopic region were identified via immunolabeling for cholera toxin, a neuronal tracer, which has been injected in the ocular globe. Then, double labeled with acetylcholinesterase histochemistry to reveal cholinergic synapses, or NADPH-diaphorase histochemistry as a nitrergic marker. Briefly, acetylcholinesterase activity was present mainly in cholera toxin labeled cell bodies of the isthmo-optic nucleus and the ectopic region indicating that retinal projecting neurons of centrifugal visual system comprise a cholinoceptive pathway. On the other hand, NADPH-diaphorase histochemistry was present in the neuropile and sparse cell bodies inside of the isthmo-optic nucleus and in ectopic neurons which were not cholera toxin positive suggesting their role in an intrinsic circuit of the centrifugal visual system. These data support the idea that these two neurochemical systems are present in distinct neuronal populations in the centrifugal visual system. 相似文献
24.
Barriers and Facilitators to Participation in Health Screening: an Umbrella Review Across Conditions
Le Bonniec Alice Sun Sophie Andrin Amandine Dima Alexandra L. Letrilliart Laurent 《Prevention science》2022,23(7):1115-1142
Prevention Science - Screening is an essential prevention practice for a number of health conditions. However, screening coverage remains generally low. Studies that investigate determinants of... 相似文献
25.
Buser Julie M. Boyd Carol J. Moyer Cheryl A. Zulu Davy Ngoma-Hazemba Alice Jones Andrew D. Lori Jody R. 《Maternal and child health journal》2021,25(8):1182-1186
Maternal and Child Health Journal - Low birthweight (LBW) is a significant public health problem in sub-Saharan Africa and LBW in rural Zambia is high. Our study explored the prevalence of LBW for... 相似文献
26.
Somba Magreat Kaaya Sylvia Siril Hellen Oljemark Kicki Ainebyona Donald McAdam Elspeth Todd James Andrew Irene McAdam Keith Simwinga Alice Mleli Neema Makongwa Samwel Haberlen Sabina Fawzi Mary C. Smith 《Prevention science》2021,22(7):940-949
Prevention Science - The NAMWEZA intervention was implemented, using a ten-session group format, to build skills targeting psychosocial vulnerabilities and enhancing HIV prevention among people... 相似文献
27.
Alice Ramondetta Simone Ribero Pietro Quaglino Paolo Broganelli 《Emerging infectious diseases》2021,27(1):281
Fluorescence-advanced videodermatoscopy is not a widespread diagnostic technique. Its application in dermatology can facilitate the diagnosis of diseases such as cutaneous larva migrans by enabling us to recognize the precise position of larva in vivo on the skin. Using this noninvasive technique, we detected a case of cutaneous larva migrans in a patient. 相似文献
28.
Katrin Gaardbo Kuhn Anne Kathrine Hvass Annette Hartvig Christiansen Steen Ethelberg Susan Alice Cowan 《Emerging infectious diseases》2021,27(4):1133
Campylobacteriosis is a disease of worldwide importance, but aspects of its transmission dynamics, particularly risk factors, are still poorly understood. We used data from a matched case-control study of 4,269 men who have sex with men (MSM) and 26,215 controls, combined with national surveillance data on Campylobacter spp., Salmonella spp., and Shigella spp., to calculate matched odds ratios (mORs) for infection among MSM and controls. MSM had higher odds of Campylobacter (mOR 14, 95% CI 10–21) and Shigella (mOR 74, 95% CI 27–203) infections, but not Salmonella (mOR 0.2, 95% CI 0–13), and were less likely than controls to have acquired Campylobacter infection abroad (χ2 = 21; p<0.001). Our results confirm that sexual contact is a risk factor for campylobacteriosis and also suggest explanations for unique features of Campylobacter epidemiology. These findings provide a baseline for updating infection risk guidelines to the general population. 相似文献
29.
30.